| Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ... Nature Neuroscience 19 (11), 1442, 2016 | 606 | 2016 |
| Multiscale analysis of independent Alzheimer’s cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus B Readhead, JV Haure-Mirande, CC Funk, MA Richards, P Shannon, ... Neuron 99 (1), 64-82. e7, 2018 | 318 | 2018 |
| In silico methods for drug repurposing and pharmacology RA Hodos, BA Kidd, K Shameer, BP Readhead, JT Dudley Wiley Interdisciplinary Reviews: Systems Biology and Medicine 8 (3), 186-210, 2016 | 137 | 2016 |
| Necroptosis activation in Alzheimer's disease A Caccamo, C Branca, IS Piras, E Ferreira, MJ Huentelman, WS Liang, ... Nature neuroscience 20 (9), 1236, 2017 | 130 | 2017 |
| L1000CDS 2: LINCS L1000 characteristic direction signatures search engine Q Duan, SP Reid, NR Clark, Z Wang, NF Fernandez, AD Rouillard, ... NPJ systems biology and applications 2 (1), 1-12, 2016 | 124 | 2016 |
| A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer SJ Vidal, V Rodriguez-Bravo, SA Quinn, R Rodriguez-Barrueco, ... Cancer cell 27 (2), 223-239, 2015 | 95 | 2015 |
| Dysregulation of miRNA-9 in a subset of schizophrenia patient-derived neural progenitor cells A Topol, S Zhu, BJ Hartley, J English, ME Hauberg, N Tran, ... Cell reports 15 (5), 1024-1036, 2016 | 93 | 2016 |
| Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach DM Ruderfer, AW Charney, B Readhead, BA Kidd, AK Kähler, PJ Kenny, ... The Lancet Psychiatry 3 (4), 350-357, 2016 | 87 | 2016 |
| Computational and experimental advances in drug repositioning for accelerated therapeutic stratification K Shameer, B Readhead, J T Dudley Current topics in medicinal chemistry 15 (1), 5-20, 2015 | 76 | 2015 |
| Cross-tissue regulatory gene networks in coronary artery disease HA Talukdar, HF Asl, RK Jain, R Ermel, A Ruusalepp, O Franzén, BA Kidd, ... Cell systems 2 (3), 196-208, 2016 | 74 | 2016 |
| Landscape of conditional eQTL in dorsolateral prefrontal cortex and co-localization with schizophrenia GWAS A Dobbyn, LM Huckins, J Boocock, LG Sloofman, BS Glicksberg, ... The American Journal of Human Genetics 102 (6), 1169-1184, 2018 | 65 | 2018 |
| Automated detection of off-label drug use K Jung, P LePendu, WS Chen, SV Iyer, B Readhead, JT Dudley, NH Shah PloS one 9 (2), e89324, 2014 | 58 | 2014 |
| Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology JV Haure-Mirande, M Audrain, T Fanutza, SH Kim, WL Klein, C Glabe, ... Acta neuropathologica 134 (5), 769-788, 2017 | 55 | 2017 |
| Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning K Shameer, BS Glicksberg, R Hodos, KW Johnson, MA Badgeley, ... Briefings in bioinformatics 19 (4), 656-678, 2018 | 53 | 2018 |
| REDD 1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids G Baida, P Bhalla, K Kirsanov, E Lesovaya, M Yakubovskaya, K Yuen, ... EMBO molecular medicine 7 (1), 42-58, 2015 | 46 | 2015 |
| Intracoronary imaging, cholesterol efflux, and transcriptomes after intensive statin treatment: the YELLOW II study AS Kini, Y Vengrenyuk, K Shameer, A Maehara, M Purushothaman, ... Journal of the American College of Cardiology 69 (6), 628-640, 2017 | 41 | 2017 |
| Detection of alpha-thalassemia in beta-thalassemia carriers and prevention of Hb Bart's hydrops fetalis through prenatal screening D Li, C Liao, J Li, X Xie, Y Huang, H Zhong haematologica 91 (5), 649-651, 2006 | 40 | 2006 |
| Enabling precision cardiology through multiscale biology and systems medicine KW Johnson, K Shameer, BS Glicksberg, B Readhead, PP Sengupta, ... JACC: Basic to Translational Science 2 (3), 311-327, 2017 | 38 | 2017 |
| Expression-based drug screening of neural progenitor cells from individuals with schizophrenia B Readhead, BJ Hartley, BJ Eastwood, DA Collier, D Evans, R Farias, ... Nature communications 9 (1), 1-11, 2018 | 33 | 2018 |
| Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma A Laganà, D Perumal, D Melnekoff, B Readhead, BA Kidd, V Leshchenko, ... Leukemia 32 (1), 120-130, 2018 | 31 | 2018 |
Joel DudleyInstitute Director and Associate Professor, Icahn School of Medicine at Mount SinaiEmail verificata su mssm.edu
