| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 4139 | 2016 |
| A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1104 | 2018 |
| Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 1052 | 2016 |
| Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma D Liu, B Schilling, D Liu, A Sucker, E Livingstone, L Jerby-Arnon, ... Nature medicine 25 (12), 1916-1927, 2019 | 718 | 2019 |
| COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ... Nature 595 (7865), 107-113, 2021 | 661 | 2021 |
| Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger elife 7, e31657, 2018 | 578 | 2018 |
| A molecular single-cell lung atlas of lethal COVID-19 JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ... Nature 595 (7865), 114-119, 2021 | 540 | 2021 |
| A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ... Nature medicine 26 (5), 792-802, 2020 | 505 | 2020 |
| Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ... Cancer discovery 8 (2), 196-215, 2018 | 481 | 2018 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 421 | 2020 |
| Spatially organized multicellular immune hubs in human colorectal cancer K Pelka, M Hofree, JH Chen, S Sarkizova, JD Pirl, V Jorgji, A Bejnood, ... Cell 184 (18), 4734-4752. e20, 2021 | 398 | 2021 |
| A single-cell landscape of high-grade serous ovarian cancer B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ... Nature medicine 26 (8), 1271-1279, 2020 | 360 | 2020 |
| Superior skin cancer classification by the combination of human and artificial intelligence A Hekler, JS Utikal, AH Enk, A Hauschild, M Weichenthal, RC Maron, ... European Journal of Cancer 120, 114-121, 2019 | 334 | 2019 |
| Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de‐differentiated state M Fallahi‐Sichani, V Becker, B Izar, GJ Baker, JR Lin, SA Boswell, P Shah, ... Molecular systems biology 13 (1), 905, 2017 | 249 | 2017 |
| Metastasis and immune evasion from extracellular cGAMP hydrolysis J Li, MA Duran, N Dhanota, WK Chatila, SE Bettigole, J Kwon, RK Sriram, ... Cancer discovery 11 (5), 1212-1227, 2021 | 199 | 2021 |
| Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion CJ Frangieh, JC Melms, PI Thakore, KR Geiger-Schuller, P Ho, ... Nature genetics 53 (3), 332-341, 2021 | 167 | 2021 |
| IFNγ-dependent tissue-immune homeostasis is co-opted in the tumor microenvironment CJ Nirschl, M Suárez-Fariñas, B Izar, S Prakadan, R Dannenfelser, ... Cell 170 (1), 127-141. e15, 2017 | 156 | 2017 |
| Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandra, ... Nature 610 (7931), 356-365, 2022 | 152 | 2022 |
| Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation A Rotem, A Janzer, B Izar, Z Ji, JG Doench, LA Garraway, K Struhl Proceedings of the National Academy of Sciences 112 (18), 5708-5713, 2015 | 130 | 2015 |
| Transcriptional mediators of treatment resistance in lethal prostate cancer MX He, MS Cuoco, J Crowdis, A Bosma-Moody, Z Zhang, K Bi, A Kanodia, ... Nature medicine 27 (3), 426-433, 2021 | 122 | 2021 |
Levi GarrawayAssociate Professor of Medicine, Harvard Medical SchoolEmail verificata su dfci.harvard.edu
