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Kevin Reynolds
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Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering
DL Stassi, SJ Kakavas, KA Reynolds, G Gunawardana, S Swanson, ...
Proceedings of the National Academy of Sciences 95 (13), 7305-7309, 1998
2281998
Antibacterial targets in fatty acid biosynthesis
HT Wright, KA Reynolds
Current opinion in microbiology 10 (5), 447-453, 2007
2172007
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine
AS Eustáquio, RP McGlinchey, Y Liu, C Hazzard, LL Beer, G Florova, ...
Proceedings of the National Academy of Sciences 106 (30), 12295-12300, 2009
1962009
Antimalarial activity of natural and synthetic prodiginines
K Papireddy, M Smilkstein, JX Kelly, Shweta, SM Salem, M Alhamadsheh, ...
Journal of medicinal chemistry 54 (15), 5296-5306, 2011
1662011
Crystal Structure of the Mycobacterium tuberculosisβ-Ketoacyl-Acyl Carrier Protein Synthase III
JN Scarsdale, G Kazanina, X He, KA Reynolds, HT Wright
Journal of Biological Chemistry 276 (23), 20516-20522, 2001
1602001
Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae
YJ Yoon, BJ Beck, BS Kim, HY Kang, KA Reynolds, DH Sherman
Chemistry & biology 9 (2), 203-214, 2002
1502002
Characterization and Analysis of the PikD Regulatory Factor in the Pikromycin Biosynthetic Pathway ofStreptomyces venezuelae
DJ Wilson, Y Xue, KA Reynolds, DH Sherman
Journal of bacteriology 183 (11), 3468-3475, 2001
1462001
Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin
BS Kim, TA Cropp, BJ Beck, DH Sherman, KA Reynolds
Journal of Biological Chemistry 277 (50), 48028-48034, 2002
1402002
Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin
TA Cropp, DJ Wilson, KA Reynolds
Nature biotechnology 18 (9), 980-983, 2000
1312000
Characterization of β-Ketoacyl-Acyl Carrier Protein Synthase III from Streptomyces glaucescens and Its Role in Initiation of Fatty Acid Biosynthesis
L Han, S Lobo, KA Reynolds
Journal of bacteriology 180 (17), 4481-4486, 1998
1291998
Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis
SJ Mo, PK Sydor, C Corre, MM Alhamadsheh, AE Stanley, SW Haynes, ...
Chemistry & biology 15 (2), 137-148, 2008
1162008
1, 2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)
X He, AME Reeve, UR Desai, GE Kellogg, KA Reynolds
Antimicrobial agents and chemotherapy 48 (8), 3093-3102, 2004
1162004
Biosynthesis of ansatrienin (mycotrienin) and naphthomycin: Identification and analysis of two separate biosynthetic gene clusters in Streptomyces collinus Tü 1892
S Chen, D von Bamberg, V Hale, M Breuer, B Hardt, R Müller, HG Floss, ...
European journal of biochemistry 261 (1), 98-107, 1999
1161999
Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains
TJ Buchholz, TW Geders, FE Bartley III, KA Reynolds, JL Smith, ...
ACS chemical biology 4 (1), 41-52, 2009
1142009
The initiating steps of a type II fatty acid synthase in Plasmodium falciparum are catalyzed by pfACP, pfMCAT, and pfKASIII
ST Prigge, X He, L Gerena, NC Waters, KA Reynolds
Biochemistry 42 (4), 1160-1169, 2003
1062003
Alteration of the Fatty Acid Profile of Streptomyces coelicolor by Replacement of the Initiation Enzyme 3-Ketoacyl Acyl Carrier Protein Synthase III (FabH)
Y Li, G Florova, KA Reynolds
Journal of bacteriology 187 (11), 3795-3799, 2005
1012005
Biosynthetic studies on ansatrienin A. Formation of the cyclohexanecarboxylic acid moiety
BS Moore, H Cho, R Casati, E Kennedy, KA Reynolds, U Mocek, ...
Journal of the American Chemical Society 115 (12), 5254-5266, 1993
991993
Distinct tRNA accommodation intermediates observed on the ribosome with the antibiotics hygromycin A and A201A
YS Polikanov, AL Starosta, MF Juette, RB Altman, DS Terry, W Lu, ...
Molecular cell 58 (5), 832-844, 2015
922015
Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster
N Palaniappan, BS Kim, Y Sekiyama, H Osada, KA Reynolds
Journal of Biological Chemistry 278 (37), 35552-35557, 2003
862003
Purification, Characterization, and Identification of Novel Inhibitors of the β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) from Staphylococcus aureus
X He, KA Reynolds
Antimicrobial agents and chemotherapy 46 (5), 1310-1318, 2002
842002
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