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Hai Ngu
Hai Ngu
Email verificata su gene.com
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Anno
Diverse brain myeloid expression profiles reveal distinct microglial activation states and aspects of Alzheimer’s disease not evident in mouse models
BA Friedman, K Srinivasan, G Ayalon, WJ Meilandt, H Lin, MA Huntley, ...
Cell reports 22 (3), 832-847, 2018
5302018
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
AS Chung, X Wu, G Zhuang, H Ngu, I Kasman, J Zhang, JM Vernes, ...
Nature medicine 19 (9), 1114-1123, 2013
4842013
Changes in the synaptic proteome in tauopathy and rescue of tau-induced synapse loss by C1q antibodies
B Dejanovic, MA Huntley, A De Mazière, WJ Meilandt, T Wu, K Srinivasan, ...
Neuron 100 (6), 1322-1336. e7, 2018
3722018
RIPK1 inhibits ZBP1-driven necroptosis during development
K Newton, KE Wickliffe, A Maltzman, DL Dugger, A Strasser, VC Pham, ...
Nature 540 (7631), 129-133, 2016
3332016
Complement C3 is activated in human AD brain and is required for neurodegeneration in mouse models of amyloidosis and tauopathy
T Wu, B Dejanovic, VD Gandham, A Gogineni, R Edmonds, S Schauer, ...
Cell reports 28 (8), 2111-2123. e6, 2019
3222019
Early postnatal astroglial cells produce multilineage precursors and neural stem cells in vivo
YM Ganat, J Silbereis, C Cave, H Ngu, GM Anderson, Y Ohkubo, LR Ment, ...
Journal of Neuroscience 26 (33), 8609-8621, 2006
2842006
Mechanical properties of actin stress fibers in living cells
L Lu, SJ Oswald, H Ngu, FCP Yin
Biophysical journal 95 (12), 6060-6071, 2008
1902008
Hepatitis C virus induces epidermal growth factor receptor activation via CD81 binding for viral internalization and entry
J Diao, H Pantua, H Ngu, L Komuves, L Diehl, G Schaefer, SB Kapadia
Journal of virology 86 (20), 10935-10949, 2012
1632012
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
SH Lee, WJ Meilandt, L Xie, VD Gandham, H Ngu, KH Barck, ...
Neuron 109 (8), 1283-1301. e6, 2021
1622021
Function of CSF1 and IL34 in macrophage homeostasis, inflammation, and cancer
WY Lin, D Xu, CD Austin, P Caplazi, K Senger, Y Sun, S Jeet, J Young, ...
Frontiers in immunology 10, 2019, 2019
1482019
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimer …
WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ...
Journal of Neuroscience 40 (9), 1956-1974, 2020
1322020
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease
CE Le Pichon, WJ Meilandt, S Dominguez, H Solanoy, H Lin, H Ngu, ...
Science translational medicine 9 (403), eaag0394, 2017
1322017
Antibody-mediated targeting of tau in vivo does not require effector function and microglial engagement
SH Lee, CE Le Pichon, O Adolfsson, V Gafner, M Pihlgren, H Lin, ...
Cell reports 16 (6), 1690-1700, 2016
1182016
Differential drug class‐specific metastatic effects following treatment with a panel of angiogenesis inhibitors
AS Chung, M Kowanetz, X Wu, G Zhuang, H Ngu, D Finkle, L Komuves, ...
The Journal of pathology 227 (4), 404-416, 2012
972012
Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors
M Merchant, J Moffat, G Schaefer, J Chan, X Wang, C Orr, J Cheng, ...
PloS one 12 (10), e0185862, 2017
932017
Ubiquitin ligase COP1 suppresses neuroinflammation by degrading c/EBPβ in microglia
A Ndoja, R Reja, SH Lee, JD Webster, H Ngu, CM Rose, DS Kirkpatrick, ...
Cell 182 (5), 1156-1169. e12, 2020
922020
Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display
PM Nair, H Flores, A Gogineni, S Marsters, DA Lawrence, RF Kelley, ...
Proceedings of the National Academy of Sciences 112 (18), 5679-5684, 2015
862015
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration
CD Pozniak, A Sengupta Ghosh, A Gogineni, JE Hanson, SH Lee, ...
Journal of Experimental Medicine 210 (12), 2553-2567, 2013
832013
Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination
K Shen, M Reichelt, RV Kyauk, H Ngu, YAA Shen, O Foreman, ...
Cell Reports 34 (10), 2021
792021
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models
B Dejanovic, T Wu, MC Tsai, D Graykowski, VD Gandham, CM Rose, ...
Nature Aging 2 (9), 837-850, 2022
782022
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