| PDZ domain binding selectivity is optimized across the mouse proteome MA Stiffler, JR Chen, VP Grantcharova, Y Lei, D Fuchs, JE Allen, ... Science 317 (5836), 364-369, 2007 | 442 | 2007 |
| Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase MA Stiffler, DR Hekstra, R Ranganathan Cell 160 (5), 882-892, 2015 | 308 | 2015 |
| Predicting PDZ domain–peptide interactions from primary sequences JR Chen, BH Chang, JE Allen, MA Stiffler, G MacBeath Nature biotechnology 26 (9), 1041-1045, 2008 | 171 | 2008 |
| Inferring protein 3D structure from deep mutation scans NJ Rollins, KP Brock, FJ Poelwijk, MA Stiffler, NP Gauthier, C Sander, ... Nature Genetics, 2019 | 147 | 2019 |
| Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays MA Stiffler, VP Grantcharova, M Sevecka, G MacBeath Journal of the American Chemical Society 128 (17), 5913-5922, 2006 | 89 | 2006 |
| Quantifying protein–protein interactions in high throughput using protein domain microarrays A Kaushansky, JE Allen, A Gordus, MA Stiffler, ES Karp, BH Chang, ... Nature protocols 5 (4), 773, 2010 | 84 | 2010 |
| Protein structure from experimental evolution MA Stiffler, FJ Poelwijk, KP Brock, RR Stein, A Riesselman, J Teyra, ... Cell Systems, doi: 10.1016/j.cels.2019.11.008, 2020 | 38 | 2020 |
| Fidelity of tRNA 5′-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors WY Chen, D Singh, LB Lai, MA Stiffler, HD Lai, MP Foster, V Gopalan Nucleic acids research 40 (10), 4666-4680, 2012 | 24 | 2012 |
| Necl‐4/Cadm4 recruits Par‐3 to the Schwann cell adaxonal membrane X Meng, P Maurel, I Lam, C Heffernan, MA Stiffler, G McBeath, JL Salzer Glia 67 (5), 884-895, 2019 | 13 | 2019 |
| 3D protein structure from genetic epistasis experiments NJ Rollins, KP Brock, FJ Poelwijk, MA Stiffler, NP Gauthier, C Sander, ... bioRxiv, 320721, 2018 | 8 | 2018 |
| A protocol for functional assessment of whole-protein saturation mutagenesis libraries utilizing high-throughput sequencing MA Stiffler, SK Subramanian, VH Salinas, R Ranganathan J. Vis. Exp, 2016 | 8 | 2016 |
| The structure-fitness landscape of pairwise relations in generative sequence models D Marshall, H Wang, M Stiffler, J Dauparas, P Koo, S Ovchinnikov BioRxiv, 2020.11. 29.402875, 2020 | 7 | 2020 |
| Simultaneous enhancement of multiple functional properties using evolution-informed protein design B Fram, I Truebridge, Y Su, AJ Riesselman, JB Ingraham, A Passera, ... bioRxiv, 2023.05. 09.539914, 2023 | 6 | 2023 |
| Efficient Design of Optimized AAV Capsids Using Multi-Property Machine Learning Models Trained across Cells, Organs and Species S Abestesh, I Akartuna, A Brown, M Cramer, F Damani, J Gerold, J Gorns, ... MOLECULAR THERAPY 29 (4), 12-12, 2021 | 1 | 2021 |
| AAV Capsid Property Estimation Is Improved by Combining Single-Molecule ID Tags and Hierarchical Bayesian Modeling of Experimental Processes K Lin, J Otwinowski, B Tobin, S Wolock, J Kwasnieski, C Sengel, R Ogurlu, ... MOLECULAR THERAPY 29 (4), 98-98, 2021 | | 2021 |
| A Systems-level Investigation of PDZ Domain Binding Selectivity MA Stiffler ProQuest, 2008 | | 2008 |
| Substrate Recognition Properties of Zea Mays RNase P: Implications for an RNase P-based Functional Genomics Approach in Plants MA Stiffler Ohio State University, 2002 | | 2002 |
Chris SanderHarvard Medical School, Broad Institute, Dana-Farber Cancer Institute, Memorial Sloan KetteringVerified email at sanderlab.org
