Gregory L. Dignon
Gregory L. Dignon
Laufer Center for Physical and Quantitative Biology, Stony Brook University
Verified email at stonybrook.edu
TitleCited byYear
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ...
The EMBO journal 36 (20), 2951-2967, 2017
1482017
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation
VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ...
Molecular cell 69 (3), 465-479. e7, 2018
782018
Sequence determinants of protein phase behavior from a coarse-grained model
GL Dignon, W Zheng, YC Kim, RB Best, J Mittal
PLoS computational biology 14 (1), e1005941, 2018
442018
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins
GL Dignon, W Zheng, RB Best, YC Kim, J Mittal
Proceedings of the National Academy of Sciences 115 (40), 9929-9934, 2018
252018
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi
Nature structural & molecular biology 26 (7), 637-648, 2019
132019
Interplay between membrane composition and structural stability of membrane-bound hIAPP
GL Dignon, GH Zerze, J Mittal
The Journal of Physical Chemistry B 121 (37), 8661-8668, 2017
102017
Temperature-Controlled Liquid–Liquid Phase Separation of Disordered Proteins
GL Dignon, W Zheng, YC Kim, J Mittal
ACS central science, 2019
92019
Simulation methods for liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, J Mittal
Current Opinion in Chemical Engineering 23, 92-98, 2019
32019
TDP-43 α-helical structure tunes liquid-liquid phase separation and function
AE Conicella, GL Dignon, GH Zerze, HB Schmidt, MD Alexandra, YC Kim, ...
BioRxiv, 640615, 2019
12019
Identifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine Its Phase Separation Behavior
B Schuster, GL Dignon, WS Tang, F Kelley, AK Ranganath, CN Jahnke, ...
bioRxiv, 2020
2020
Models for liquid-liquid phase separation of disordered proteins
W Zheng, G Dignon, M Brown, R Best, Y Kim, J Mittal
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Sequence Determinants of Protein Phase Separation of the Intrinsically Disordered RGG Domain from LAF-1
BS Schuster, G Dignon, C Jahnke, MC Good, DA Hammer, J Mittal
Biophysical Journal 116 (3), 453a-454a, 2019
2019
A High-Throughput Approach to Phase Separation of Disordered Proteins
GL Dignon, W Zheng, Y Kim, J Mittal
Biophysical Journal 116 (3), 350a, 2019
2019
Multiscale Model of the Formin Homology 1 Domain Illustrates its Role in Regulation of Actin Polymerization
BG Horan, G Zerze, GL Dignon, YC Kim, D Vavylonis, J Mittal
Biophysical Journal 114 (3), 144a, 2018
2018
Coarse-Grained Simulations of Intrinsically Disordered Proteins in the Context of Liquid-Liquid Phase Separation
GL Dignon, W Zheng, YC Kim, J Mittal, R Best
Biophysical Journal 114 (3), 431a-432a, 2018
2018
A Novel Coarse-Grained Model to Study Liquid-Liquid Phase Separation of Disordered Proteins
GL Dignon, W Zheng, R Best, J Mittal
Biophysical Journal 112 (3), 200a, 2017
2017
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