Gregory L. Dignon
Gregory L. Dignon
Laufer Center for Physical and Quantitative Biology, Stony Brook University
Verified email at stonybrook.edu
Title
Cited by
Cited by
Year
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ...
The EMBO journal 36 (20), 2951-2967, 2017
2872017
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation
VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ...
Molecular cell 69 (3), 465-479. e7, 2018
1742018
Sequence determinants of protein phase behavior from a coarse-grained model
GL Dignon, W Zheng, YC Kim, RB Best, J Mittal
PLoS computational biology 14 (1), e1005941, 2018
1342018
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi
Nature structural & molecular biology 26 (7), 637-648, 2019
1252019
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins
GL Dignon, W Zheng, RB Best, YC Kim, J Mittal
Proceedings of the National Academy of Sciences 115 (40), 9929-9934, 2018
1042018
Temperature-controlled liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, YC Kim, J Mittal
ACS central science 5 (5), 821-830, 2019
652019
TDP-43 α-helical structure tunes liquid–liquid phase separation and function
AE Conicella, GL Dignon, GH Zerze, HB Schmidt, MD Alexandra, YC Kim, ...
Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020
542020
Biomolecular phase separation: From molecular driving forces to macroscopic properties
GL Dignon, RB Best, J Mittal
Annual review of physical chemistry 71, 53-75, 2020
502020
Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior
BS Schuster, GL Dignon, WS Tang, FM Kelley, AK Ranganath, ...
Proceedings of the National Academy of Sciences 117 (21), 11421-11431, 2020
432020
Simulation methods for liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, J Mittal
Current opinion in chemical engineering 23, 92-98, 2019
332019
Hydropathy patterning complements charge patterning to describe conformational preferences of disordered proteins
W Zheng, G Dignon, M Brown, YC Kim, J Mittal
The journal of physical chemistry letters 11 (9), 3408-3415, 2020
192020
Interplay between membrane composition and structural stability of membrane-bound hIAPP
GL Dignon, GH Zerze, J Mittal
The Journal of Physical Chemistry B 121 (37), 8661-8668, 2017
182017
Sequence dependent phase separation of protein-polynucleotide mixtures elucidated using molecular simulations
RM Regy, GL Dignon, W Zheng, YC Kim, J Mittal
Nucleic acids research 48 (22), 12593-12603, 2020
132020
Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations
W Zheng, GL Dignon, N Jovic, X Xu, RM Regy, NL Fawzi, YC Kim, ...
The Journal of Physical Chemistry B, 2020
102020
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
VH Ryan, TM Perdikari, MT Naik, CF Saueressig, J Lins, GL Dignon, ...
The EMBO journal 40 (3), e105001, 2021
72021
A predictive coarse-grained model for position-specific effects of post-translational modifications on disordered protein phase separation
TM Perdikari, N Jovic, GL Dignon, YC Kim, NL Fawzi, J Mittal
bioRxiv, 2020
62020
A predictive coarse-grained model for position-specific effects of post-translational modifications
TM Perdikari, N Jovic, GL Dignon, YC Kim, NL Fawzi, J Mittal
Biophysical Journal 120 (7), 1187-1197, 2021
52021
Alpha-Helical Structure in TDP-43 Tunes Liquid-liquid Phase Separation and Cellular Function
AE Conicella, G Dignon, GH Zerze, B Schmidt, MD Alexandra, Y Kim, ...
Biophysical Journal 118 (3), 5a-6a, 2020
12020
Sequence Determinants of Protein Phase Separation of the Intrinsically Disordered RGG Domain from LAF-1
BS Schuster, G Dignon, C Jahnke, MC Good, DA Hammer, J Mittal
Biophysical Journal 116 (3), 453a-454a, 2019
12019
Coarse-Grained Simulations of Intrinsically Disordered Proteins in the Context of Liquid-Liquid Phase Separation
GL Dignon, W Zheng, YC Kim, J Mittal, R Best
Biophysical Journal 114 (3), 431a-432a, 2018
12018
The system can't perform the operation now. Try again later.
Articles 1–20