Gregory L. Dignon
Gregory L. Dignon
Laufer Center for Physical and Quantitative Biology, Stony Brook University
Verified email at stonybrook.edu
Title
Cited by
Cited by
Year
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ...
The EMBO journal 36 (20), 2951-2967, 2017
1712017
Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation
VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ...
Molecular cell 69 (3), 465-479. e7, 2018
932018
Sequence determinants of protein phase behavior from a coarse-grained model
GL Dignon, W Zheng, YC Kim, RB Best, J Mittal
PLoS computational biology 14 (1), e1005941, 2018
552018
Relation between single-molecule properties and phase behavior of intrinsically disordered proteins
GL Dignon, W Zheng, RB Best, YC Kim, J Mittal
Proceedings of the National Academy of Sciences 115 (40), 9929-9934, 2018
402018
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi
Nature structural & molecular biology 26 (7), 637-648, 2019
202019
Temperature-controlled liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, YC Kim, J Mittal
ACS central science 5 (5), 821-830, 2019
152019
Interplay between membrane composition and structural stability of membrane-bound hIAPP
GL Dignon, GH Zerze, J Mittal
The Journal of Physical Chemistry B 121 (37), 8661-8668, 2017
122017
Simulation methods for liquid–liquid phase separation of disordered proteins
GL Dignon, W Zheng, J Mittal
Current Opinion in Chemical Engineering 23, 92-98, 2019
42019
TDP-43 α-helical structure tunes liquid–liquid phase separation and function
AE Conicella, GL Dignon, GH Zerze, HB Schmidt, MD Alexandra, YC Kim, ...
Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020
12020
Alpha-Helical Structure in TDP-43 Tunes Liquid-liquid Phase Separation and Cellular Function
AE Conicella, G Dignon, GH Zerze, B Schmidt, MD Alexandra, Y Kim, ...
Biophysical Journal 118 (3), 5a-6a, 2020
2020
Impact of Hydrophobic Patterning on Conformational Ensemble of Disordered Proteins
W Zheng, G Dignon, M Brown, J Mittal
Biophysical Journal 118 (3), 214a, 2020
2020
Studying RNA Modulated Protein Liquid-Liquid Phase Separation using Coarse-Grained Models
RM Regy, GL Dignon, Y Kim, J Mittal
Biophysical Journal 118 (3), 537a, 2020
2020
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning & reduces neurodegeneration
VH Ryan, TM Perdikari, MT Naik, CF Saueressig, J Lins, GL Dignon, ...
bioRxiv, 2020
2020
Hydropathy patterning complements charge patterning to describe conformational preferences of disordered proteins
W Zheng, GL Dignon, M Brown, YC Kim, J Mittal
The Journal of Physical Chemistry Letters, 2020
2020
Identifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine Its Phase Separation Behavior
B Schuster, GL Dignon, WS Tang, F Kelley, AK Ranganath, CN Jahnke, ...
bioRxiv, 2020
2020
Models for liquid-liquid phase separation of disordered proteins
W Zheng, G Dignon, M Brown, R Best, Y Kim, J Mittal
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Sequence Determinants of Protein Phase Separation of the Intrinsically Disordered RGG Domain from LAF-1
BS Schuster, G Dignon, C Jahnke, MC Good, DA Hammer, J Mittal
Biophysical Journal 116 (3), 453a-454a, 2019
2019
A High-Throughput Approach to Phase Separation of Disordered Proteins
GL Dignon, W Zheng, Y Kim, J Mittal
Biophysical Journal 116 (3), 350a, 2019
2019
A Molecular View of Self-Assembly and Liquid-Liquid Phase Separation of Intrinsically Disordered Proteins
GL Dignon
Lehigh University, 2019
2019
Multiscale Model of the Formin Homology 1 Domain Illustrates its Role in Regulation of Actin Polymerization
BG Horan, G Zerze, GL Dignon, YC Kim, D Vavylonis, J Mittal
Biophysical Journal 114 (3), 144a, 2018
2018
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Articles 1–20