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Jen-chieh Chuang
Jen-chieh Chuang
Takeda Pharmaceuticals
Verified email at takeda.com - Homepage
Title
Cited by
Cited by
Year
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility
JW Hill, CF Elias, M Fukuda, KW Williams, ED Berglund, WL Holland, ...
Cell metabolism 11 (4), 286-297, 2010
4502010
Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner
M Perello, I Sakata, S Birnbaum, JC Chuang, S Osborne-Lawrence, ...
Biological psychiatry 67 (9), 880-886, 2010
4262010
Ghrelin mediates stress-induced food-reward behavior in mice
JC Chuang, M Perello, I Sakata, S Osborne-Lawrence, JM Savitt, M Lutter, ...
The Journal of clinical investigation 121 (7), 2684-2692, 2011
3792011
Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice
ED Berglund, CR Vianna, J Donato, MH Kim, JC Chuang, CE Lee, ...
The Journal of clinical investigation 122 (3), 1000-1009, 2012
3702012
Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice
T Fujikawa, JC Chuang, I Sakata, G Ramadori, R Coppari
Proceedings of the National Academy of Sciences 107 (40), 17391-17396, 2010
2522010
Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin
Q Wang, C Liu, A Uchida, JC Chuang, A Walker, T Liu, ...
Molecular metabolism 3 (1), 64-72, 2014
2492014
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
N Gustavsson, Y Lao, A Maximov, JC Chuang, E Kostromina, JJ Repa, ...
Proceedings of the National Academy of Sciences 105 (10), 3992-3997, 2008
2062008
The nonsteroidal farnesoid X receptor agonist cilofexor (GS‐9674) improves markers of cholestasis and liver injury in patients with primary sclerosing cholangitis
M Trauner, A Gulamhusein, B Hameed, S Caldwell, ML Shiffman, ...
Hepatology 70 (3), 788-801, 2019
2042019
Arid1a has context-dependent oncogenic and tumor suppressor functions in liver cancer
X Sun, SC Wang, Y Wei, X Luo, Y Jia, L Li, P Gopal, M Zhu, I Nassour, ...
Cancer cell 32 (5), 574-589. e6, 2017
1982017
Combination therapies including cilofexor and firsocostat for bridging fibrosis and cirrhosis attributable to NASH
R Loomba, M Noureddin, KV Kowdley, A Kohli, A Sheikh, G Neff, ...
Hepatology 73 (2), 625-643, 2021
1842021
Ghrelin directly stimulates glucagon secretion from pancreatic α-cells
JC Chuang, I Sakata, D Kohno, M Perello, S Osborne-Lawrence, JJ Repa, ...
Molecular Endocrinology 25 (9), 1600-1611, 2011
1712011
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis
AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ...
Molecular psychiatry 20 (4), 500-508, 2015
1692015
Ghrelin's roles in stress, mood, and anxiety regulation
JC Chuang, JM Zigman
International journal of peptides 2010, 2010
1622010
Chronic social defeat stress disrupts regulation of lipid synthesis [S]
JC Chuang, H Cui, BL Mason, M Mahgoub, AL Bookout, GY Hana, ...
Journal of lipid research 51 (6), 1344-1353, 2010
1492010
Suppression of the SWI/SNF component Arid1a promotes mammalian regeneration
X Sun, JC Chuang, M Kanchwala, L Wu, C Celen, L Li, H Liang, S Zhang, ...
Cell stem cell 18 (4), 456-466, 2016
1452016
A β3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress
JC Chuang, V Krishnan, GY Hana, B Mason, H Cui, MB Wilkinson, ...
Biological psychiatry 67 (11), 1075-1082, 2010
1262010
Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain
M Perello, MM Scott, I Sakata, CE Lee, JC Chuang, S Osborne‐Lawrence, ...
Journal of Comparative Neurology 520 (2), 281-294, 2012
1102012
Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells
I Sakata, WM Park, AK Walker, PK Piper, JC Chuang, ...
American Journal of Physiology-Endocrinology and Metabolism 302 (10), E1300 …, 2012
1072012
Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment
C Celen, JC Chuang, X Luo, N Nijem, AK Walker, F Chen, S Zhang, ...
Elife 6, e25730, 2017
1032017
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver
Y Xu, ED Berglund, JW Sohn, WL Holland, JC Chuang, M Fukuda, ...
Nature neuroscience 13 (12), 1457-1459, 2010
992010
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