Structure–activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain G Cuzzucoli Crucitti, M Métifiot, L Pescatori, A Messore, VN Madia, ... Journal of medicinal chemistry 58 (4), 1915-1928, 2015 | 85 | 2015 |
Activity of caffeic acid derivatives against Candida albicans biofilm D De Vita, L Friggeri, FD D’Auria, F Pandolfi, F Piccoli, S Panella, ... Bioorganic & medicinal chemistry letters 24 (6), 1502-1505, 2014 | 81 | 2014 |
Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase R Costi, M Métifiot, S Chung, G Cuzzucoli Crucitti, K Maddali, L Pescatori, ... Journal of Medicinal Chemistry 57 (8), 3223-3234, 2014 | 66 | 2014 |
6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic Acids as Dual Inhibitors of Recombinant HIV-1 Integrase and Ribonuclease H, Synthesized by a Parallel … R Costi, M Métifiot, F Esposito, G Cuzzucoli Crucitti, L Pescatori, ... Journal of medicinal chemistry 56 (21), 8588-8598, 2013 | 64 | 2013 |
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives D De Vita, L Scipione, S Tortorella, P Mellini, B Di Rienzo, G Simonetti, ... European Journal of Medicinal Chemistry 49, 334-342, 2012 | 59 | 2012 |
Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma cruzi Sterol 14α-Demethylase: Two Regions of the Enzyme Molecule Potentiate Its Inhibition L Friggeri, TY Hargrove, G Rachakonda, AD Williams, Z Wawrzak, ... Journal of medicinal chemistry 57 (15), 6704-6717, 2014 | 48 | 2014 |
N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase L Pescatori, M Métifiot, S Chung, T Masoaka, G Cuzzucoli Crucitti, ... Journal of medicinal chemistry 58 (11), 4610-4623, 2015 | 47 | 2015 |
Discovery of in vitro antitubercular agents through in silico ligand-based approaches D De Vita, F Pandolfi, R Cirilli, L Scipione, R Di Santo, L Friggeri, M Mori, ... European Journal of Medicinal Chemistry 121, 169-180, 2016 | 27 | 2016 |
In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51 D De Vita, F Moraca, C Zamperini, F Pandolfi, R Di Santo, A Matheeussen, ... European Journal of Medicinal Chemistry 113, 28-33, 2016 | 27 | 2016 |
Dithionite adducts of pyridinium salts: regioselectivity of formation and mechanisms of decomposition V Carelli, F Liberatore, L Scipione, B Di Rienzo, S Tortorella Tetrahedron 61 (43), 10331-10337, 2005 | 26 | 2005 |
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target R Costi, G Cuzzucoli Crucitti, L Pescatori, A Messore, L Scipione, ... Journal of Medicinal Chemistry 56 (18), 7431-7441, 2013 | 24 | 2013 |
New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi L Friggeri, L Scipione, R Costi, M Kaiser, F Moraca, C Zamperini, B Botta, ... ACS medicinal chemistry letters 4 (6), 538-541, 2013 | 21 | 2013 |
On the regio-and stereoselectivity of pyridinyl radical dimerization V Carelli, F Liberatore, A Casini, S Tortorella, L Scipione, B Di Rienzo New Journal of Chemistry 22 (9), 999-1004, 1998 | 21 | 1998 |
1H-, 13C-, 31P-NMR studies and conformational analysis of NADP+, NADPH coenzymes and of dimers from electrochemical reduction of NADP+ E Ragg, L Scaglioni, R Mondelli, I Carelli, A Casini, S Tortorella Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1991 | 20 | 1991 |
Discovery of N-aryl-naphthylamines as in vitro inhibitors of the interaction between HIV integrase and the cofactor LEDGF/p75 GC Crucitti, L Pescatori, A Messore, VN Madia, G Pupo, F Saccoliti, ... European Journal of Medicinal Chemistry 101, 288-294, 2015 | 19 | 2015 |
Reactivity of pseudobases from pyridinium salts competition between hydrogen transfer and ring-opening reactions FM Moracci, S Tortorella, B Di Rienzo, F Liberatore Tetrahedron 35 (21), 2591-2593, 1979 | 17 | 1979 |
Covalent adducts from 1, 3-disubstituted pyridinium salts and piperidine FM Moracci, B Di Rienzo, S Tortorella, F Liberators Tetrahedron 36 (6), 785-789, 1980 | 16 | 1980 |
1H-NMR study and structure determination of 4, 4-and 4, 6-dimers from electrochemical reduction of NADP+ E Ragg, L Scaglioni, R Mondelli, V Carelli, I Carelli, A Casini, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1991 | 15 | 1991 |
Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats V Rispoli, D Rotiroti, V Carelli, F Liberatore, L Scipione, R Marra, ... Pharmacology Biochemistry and Behavior 78 (4), 667-673, 2004 | 14 | 2004 |
Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents L Friggeri, F Ballante, R Ragno, I Musmuca, D De Vita, F Manetti, M Biava, ... Journal of chemical information and modeling 53 (6), 1463-1474, 2013 | 12 | 2013 |