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David E. Leahy
David E. Leahy
The Discovery Bus Ltd
Verified email at davideleahy.com - Homepage
Title
Cited by
Cited by
Year
Cross-validation pitfalls when selecting and assessing regression and classification models
D Krstajic, LJ Buturovic, DE Leahy, S Thomas
Journal of cheminformatics 6, 1-15, 2014
9182014
Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases
T Rodgers, D Leahy, M Rowland
Journal of pharmaceutical sciences 94 (6), 1259-1276, 2005
7652005
Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases
T Rodgers, D Leahy, M Rowland
Journal of pharmaceutical sciences 94 (6), 1259-1276, 2005
7652005
GPTIPS: an open source genetic programming toolbox for multigene symbolic regression
DP Searson, DE Leahy, MJ Willis
Proceedings of the International multiconference of engineers and computer …, 2010
4952010
Metabolism: A Bottleneck in In Vitro Toxicological Test Development: The Report and Recommendations of ECVAM Workshop 54
S Coecke, H Ahr, BJ Blaauboer, S Bremer, S Casati, J Castell, R Combes, ...
Alternatives to Laboratory Animals 34 (1), 49-84, 2006
2122006
Intrinsic molecular volume as a measure of the cavity term in linear solvation energy relationships: octanol-water partition coefficients and aqueous solubilities
DE Leahy
Journal of pharmaceutical sciences 75 (7), 629-636, 1986
1851986
Tissue distribution of basic drugs: accounting for enantiomeric, compound and regional differences amongst β-blocking drugs in rat
T Rodgers, D Leahy, M Rowland
Journal of pharmaceutical sciences 94 (6), 1237-1248, 2005
1302005
Model solvent systems for QSAR Part I. Propylene glycol dipelargonate (PGDP). A new standard solvent for use in partition coefficient determination
DE Leahy, PJ Taylor, AR Wait
Quantitative Structure‐Activity Relationships 8 (1), 17-31, 1989
1181989
Model Solvent Systems for QSAR. Part 3. An LSER Analysis of the “Critical Quartet”. New Light on Hydrogen Bond Strength and Directionality.
DE Leahy, JJ Morris, PJ Taylor, AR Wait
ChemInform 23 (31), no-no, 1992
1091992
Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in human plasma
FA Brightman, DE Leahy, GE Searle, S Thomas
Drug metabolism and disposition 34 (1), 94-101, 2006
722006
QSAR, rational approaches to the design of bioactive compounds
C Silipo, A Vittoria
71*1991
Automated QSPR through competitive workflow
J Cartmell, S Enoch, D Krstajic, DE Leahy
Journal of computer-aided molecular design 19 (11), 821-833, 2005
662005
Model solvent systems for qsar. 2. Fragment values (F-Values) for the critical quartet
DE Leahy, JJ Morris, PJ Taylor, AR Wait
J Chem Soc Perk Trans 2, 4, 1992
661992
Linear solvation energy relationships. A comparison of molar volume and intrinsic molecular volume as measures of the cavity term in reversed phase liquid chromatography
DE Leahy, PW Carr, RS Pearlman, RW Taft, MJ Kamlet
Chromatographia 21 (8), 473-477, 1986
651986
The lithiation of gem-bis (pyrazol-1-yl) alkanes
AR Katritzky, AE Abdel-Rahman, DE Leahy, OA Schwarz
Tetrahedron 39 (24), 4133-4142, 1983
611983
The lithiation of gem-bis (pyrazol-1-yl) alkanes
AR Katritzky, AE Abdel-Rahman, DE Leahy, OA Schwarz
Tetrahedron 39 (24), 4133-4142, 1983
611983
Partition and distribution coefficients of solutes and drugs in brush border membrane vesicles
CJ Alcorn, RJ Simpson, DE Leahy, TJ Peters
Biochemical pharmacology 45 (9), 1775-1782, 1993
601993
Application of a generic physiologically based pharmacokinetic model to the estimation of xenobiotic levels in rat plasma
FA Brightman, DE Leahy, GE Searle, S Thomas
Drug metabolism and disposition 34 (1), 84-93, 2006
552006
QSAR, rational approaches to the design of bioactive compounds
C Silipo, A Vittoria
441991
Integrating invitro ADMET data through generic physiologically based pharmacokinetic models
DE Leahy
Expert opinion on drug metabolism & toxicology 2 (4), 619-628, 2006
422006
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