Perrotti Danilo
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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
M Fabbri, A Paone, F Calore, R Galli, E Gaudio, R Santhanam, F Lovat, ...
Proceedings of the National Academy of Sciences 109 (31), E2110-E2116, 2012
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly†…
R Garzon, S Liu, M Fabbri, Z Liu, CEA Heaphy, E Callegari, S Schwind, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6411-6418, 2009
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI‐3k/Akt‐dependent pathway
T Skorski, A Bellacosa, M Nieborowska‐Skorska, M Majewski, R Martinez, ...
The EMBO journal 16 (20), 6151-6161, 1997
Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study
P Paschka, G Marcucci, AS Ruppert, K Mrůzek, H Chen, RA Kittles, ...
Journal of Clinical Oncology 24 (24), 3904-3911, 2006
The biology of CML blast crisis
B Calabretta, D Perrotti
Blood 103 (11), 4010-4022, 2004
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts
AM Eiring, JG Harb, P Neviani, C Garton, JJ Oaks, R Spizzo, S Liu, ...
Cell 140 (5), 652-665, 2010
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
P Neviani, R Santhanam, R Trotta, M Notari, BW Blaser, S Liu, H Mao, ...
Cancer cell 8 (5), 355-368, 2005
Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
F Pichiorri, SS Suh, A Rocci, L De Luca, C Taccioli, R Santhanam, ...
Cancer cell 18 (4), 367-381, 2010
Chronic myeloid leukemia: mechanisms of blastic transformation
D Perrotti, C Jamieson, J Goldman, T Skorski
The Journal of clinical investigation 120 (7), 2254-2264, 2010
BCR-ABL suppresses C/EBPα expression through inhibitory action of hnRNP E2
D Perrotti, V Cesi, R Trotta, C Guerzoni, G Santilli, K Campbell, A Iervolino, ...
Nature genetics 30 (1), 48-58, 2002
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia
P Neviani, R Santhanam, JJ Oaks, AM Eiring, M Notari, BW Blaser, S Liu, ...
The Journal of clinical investigation 117 (9), 2408-2421, 2007
Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells
HG JÝrgensen, EK Allan, NE Jordanides, JC Mountford, TL Holyoake
Blood 109 (9), 4016-4019, 2007
Protein phosphatase 2A: a target for anticancer therapy
D Perrotti, P Neviani
The lancet oncology 14 (6), e229-e238, 2013
Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic†…
S Costinean, SK Sandhu, IM Pedersen, E Tili, R Trotta, D Perrotti, ...
Blood, The Journal of the American Society of Hematology 114 (7), 1374-1382, 2009
Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study
G Marcucci, CD Baldus, AS Ruppert, MD Radmacher, K Mrůzek, ...
J Clin Oncol 23 (36), 9234-9242, 2005
Sp1/NFκB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia
S Liu, LC Wu, J Pang, R Santhanam, S Schwind, YZ Wu, CJ Hickey, J Yu, ...
Cancer cell 17 (4), 333-347, 2010
BCR/ABL activates mdm2 mRNA translation via the La antigen
R Trotta, T Vignudelli, O Candini, RV Intine, L Pecorari, C Guerzoni, ...
Cancer cell 3 (2), 145-160, 2003
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ...
EMBO molecular medicine 5 (1), 105-121, 2013
A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation
M Notari, P Neviani, R Santhanam, BW Blaser, JS Chang, A Galietta, ...
Blood 107 (6), 2507-2516, 2006
Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia
MA Caligiuri, R Briesewitz, J Yu, L Wang, M Wei, KJ Arnoczky, ...
Blood, The Journal of the American Society of Hematology 110 (3), 1022-1024, 2007
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