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Lautaro Alvarez
Lautaro Alvarez
Verified email at qo.fcen.uba.ar
Title
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Cited by
Year
Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor
DM Presman, MF Ogara, M Stortz, LD Alvarez, JR Pooley, RL Schiltz, ...
PLoS biology 12 (3), e1001813, 2014
1372014
Synthesis and biological evaluation of novel substituted pyrrolo [1, 2-a] quinoxaline derivatives as inhibitors of the human protein kinase CK2
J Guillon, M Le Borgne, C Rimbault, S Moreau, S Savrimoutou, N Pinaud, ...
European Journal of Medicinal Chemistry 65, 205-222, 2013
1022013
Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids
DM Presman, LD Alvarez, V Levi, S Eduardo, MA Digman, MA Martí, ...
PloS one 5 (10), e13279, 2010
572010
Structure of the glucocorticoid receptor, a flexible protein that can adapt to different ligands
AS Veleiro, LD Alvarez, SL Eduardo, G Burton
ChemMedChem 5 (5), 649-659, 2010
342010
New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects
A Pecci, LD Alvarez, AS Veleiro, NR Ceballos, CP Lantos, G Burton
The Journal of Steroid Biochemistry and Molecular Biology 113 (3-5), 155-162, 2009
272009
Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6, 19-epoxyprogesterone
LD Álvarez, MA Martí, AS Veleiro, DM Presman, DA Estrin, A Pecci, ...
Journal of medicinal chemistry 51 (5), 1352-1360, 2008
262008
Hemisuccinate of 21‐hydroxy‐6, 19‐epoxyprogesterone: a tissue‐specific modulator of the glucocorticoid receptor
LD Álvarez, MA Martí, AS Veleiro, RI Misico, DA Estrin, A Pecci, G Burton
ChemMedChem: Chemistry Enabling Drug Discovery 3 (12), 1869-1877, 2008
222008
Ruthenium-catalyzed synthesis of pyrrolo [1, 2-a] quinoxaline derivatives from 1-(2-aminophenyl) pyrroles and sulfoxonium ylides
XF Cui, FP Hu, XQ Zhou, ZZ Zhan, GS Huang
Synlett 31 (12), 1205-1210, 2020
192020
Structure and dynamics of neurosteroid binding to the α1β2γ2 GABAA receptor
LD Alvarez, A Pecci
The Journal of steroid biochemistry and molecular biology 182, 72-80, 2018
192018
Acetic Acid Catalysed One-Pot Synthesis of Pyrrolo [1, 2-a] quinoxaline Derivatives
PNM Allan, MI Ostrowska, B Patel
Synlett 30 (19), 2148-2152, 2019
182019
In Search of GABAA Receptor’s Neurosteroid Binding Sites: Miniperspective
LD Alvarez, A Pecci, DA Estrin
Journal of Medicinal Chemistry 62 (11), 5250-5260, 2018
182018
Exploring the molecular basis of neurosteroid binding to the β3 homopentameric GABAA receptor
LD Alvarez, DA Estrin
The Journal of Steroid Biochemistry and Molecular Biology 154, 159-167, 2015
152015
Synthesis of C (1)–C (11) oxygen-bridged pregnanes
AS Veleiro, PJ Taich, LD Alvarez, PH Di Chenna, G Burton
Tetrahedron letters 46 (24), 4235-4238, 2005
152005
Synthesis and GABAA receptor activity of oxygen-bridged neurosteroid analogs
LD Alvarez, AS Veleiro, RF Baggio, MT Garland, VC Edelsztein, H Coirini, ...
Bioorganic & medicinal chemistry 16 (7), 3831-3838, 2008
142008
Structural insights into the ligand binding domain of the glucocorticoid receptor: a molecular dynamics study
NRC Alves, A Pecci, LD Alvarez
Journal of Chemical Information and Modeling 60 (2), 794-804, 2019
132019
Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity
LD Álvarez, MV Dansey, DY Grinman, D Navalesi, GA Samaja, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
132015
Exploring the molecular basis of action of ring D aromatic steroidal antiestrogens
LD Alvarez, AS Veleiro, G Burton
Proteins: Structure, Function, and Bioinformatics 83 (7), 1297-1306, 2015
132015
Synthetic DAF-12 modulators with potential use in controlling the nematode life cycle
MV Dansey, LD Alvarez, G Samaja, DS Escudero, AS Veleiro, A Pecci, ...
Biochemical Journal 465 (1), 175-184, 2015
122015
The Caenorhabditis elegans DAF‐12 nuclear receptor: Structure, dynamics, and interaction with ligands
LD Alvarez, PA Manez, DA Estrin, G Burton
Proteins: Structure, Function, and Bioinformatics 80 (7), 1798-1809, 2012
122012
Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor
M Rey, MS Kruse, LD Alvarez, AA Ghini, AS Veleiro, G Burton, H Coirini
Experimental neurology 249, 49-58, 2013
112013
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