Human aldo–keto reductases: function, gene regulation, and single nucleotide polymorphisms TM Penning, JE Drury Archives of biochemistry and biophysics 464 (2), 241-250, 2007 | 317 | 2007 |
Permeation and activation of the M2 ion channel of influenza A virus JA Mould, JE Drury, SM Frings, UB Kaupp, A Pekosz, RA Lamb, LH Pinto Journal of Biological Chemistry 275 (40), 31038-31050, 2000 | 182 | 2000 |
Crystal structure of human liver Δ4-3-ketosteroid 5β-reductase (AKR1D1) and implications for substrate binding and catalysis L Di Costanzo, JE Drury, TM Penning, DW Christianson Journal of Biological Chemistry 283 (24), 16830-16839, 2008 | 74 | 2008 |
Inhibition of human steroid 5β-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex JE Drury, L Di Costanzo, TM Penning, DW Christianson Journal of Biological Chemistry 284 (30), 19786-19790, 2009 | 72 | 2009 |
Molecular basis of 1-deoxygalactonojirimycin arylthiourea binding to human α-galactosidase A: pharmacological chaperoning efficacy on Fabry disease mutants Y Yu, T Mena-Barragan, K Higaki, JL Johnson, JE Drury, RL Lieberman, ... ACS chemical biology 9 (7), 1460-1469, 2014 | 55 | 2014 |
Characterization of disease-related 5β-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency JE Drury, R Mindnich, TM Penning Journal of Biological Chemistry 285 (32), 24529-24537, 2010 | 52 | 2010 |
Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1) M Chen, JE Drury, TM Penning Steroids 76 (5), 484-490, 2011 | 50 | 2011 |
Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1) L Di Costanzo, JE Drury, DW Christianson, TM Penning Molecular and cellular endocrinology 301 (1-2), 191-198, 2009 | 36 | 2009 |
Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector BA Piras, JE Drury, CL Morton, Y Spence, TD Lockey, AC Nathwani, ... Molecular Therapy-Methods & Clinical Development 3, 16015, 2016 | 26 | 2016 |
Conversion of Human Steroid 5β-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H EXAMPLE OF PERFECT ENZYME ENGINEERING M Chen, JE Drury, DW Christianson, TM Penning Journal of Biological Chemistry 287 (20), 16609-16622, 2012 | 19 | 2012 |
The effect of disease associated point mutations on 5β-reductase (AKR1D1) enzyme function R Mindnich, JE Drury, TM Penning Chemico-biological interactions 191 (1-3), 250-254, 2011 | 17 | 2011 |
Conversion of scFv peptide-binding specificity for crystal chaperone development JC Pai, JA Culver, JE Drury, RS Motani, RL Lieberman, JA Maynard Protein Engineering, Design & Selection 24 (5), 419-428, 2011 | 17 | 2011 |
Catalytic properties of intramembrane aspartyl protease substrate hydrolysis evaluated using a FRET peptide cleavage assay SH Naing, KM Vukoti, JE Drury, JL Johnson, S Kalyoncu, SE Hill, ... ACS chemical biology 10 (9), 2166-2174, 2015 | 15 | 2015 |
A*-3-Ketosteroid 53-Reductase (AKR1D1): Properties and Role in JE Drury, T Penning Enzymology and Molecular Biology of Carbonyl Metabolism 13, 332, 2007 | 3* | 2007 |
Structure–function relationship of the M2 ion channel of influenza A virus JA Mould, K Shuck, JE Drury, SM Frings, UB Kaupp, A Pekosz, RA Lamb, ... International Congress Series 1219, 389-396, 2001 | 1 | 2001 |
Abstract/Details JE Drury, TM Penning | 1* | |
Structural Analysis of the Change-of-Function E120H Mutation in Human Liver triangle (4)-3-Ketosteroid 5 beta-Reductase (AKR1D1). M Chen, JE Drury, TM Penning, DW Christianson ENDOCRINE REVIEWS 31 (3), 2010 | | 2010 |
Structural Analysis of the Change-of-Function E120H Mutation in Human Liver Δ4-3-Ketosteroid 5β-Reductase (AKR1D1). M Chen, JE Drury, TM Penning, DW Christianson Posters I, P3-25-P3-25, 2010 | | 2010 |
Expression, characterization, and structural analysis of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and its disease-related mutant P133R JE Drury University of Pennsylvania, 2009 | | 2009 |
BIOL 16-Cortisone, progesterone and testosterone binding in the active site of delta (4)-3-ketosteroid 5 beta-reductase: A crystallographic study L Di Costanzo, JE Drury, TM Penning, DW Christianson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 236, 2008 | | 2008 |