Identification of novel substrates and structure–activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2 R Hendrickx, JG Johansson, C Lohmann, RM Jenvert, A Blomgren, ... Journal of medicinal chemistry 56 (18), 7232-7242, 2013 | 99 | 2013 |
Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ... Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018 | 67 | 2018 |
Selective nonsteroidal glucocorticoid receptor modulators for the inhaled treatment of pulmonary diseases M Hemmerling, S Nilsson, K Edman, S Eirefelt, W Russell, R Hendrickx, ... Journal of Medicinal Chemistry 60 (20), 8591-8605, 2017 | 54 | 2017 |
Translational model to predict pulmonary pharmacokinetics and efficacy in man for inhaled bronchodilators R Hendrickx, E Lamm Bergström, DLI Janzén, M Fridén, U Eriksson, ... CPT: pharmacometrics & systems pharmacology 7 (3), 147-157, 2018 | 37 | 2018 |
An investigation by means of correlation analysis into the mechanisms of oxidation of aryl methyl sulfides and sulfoxides by dimethyldioxirane in various solvents P Hanson, RAAJ Hendrickx, JRL Smith Organic & Biomolecular Chemistry 6 (4), 745-761, 2008 | 35 | 2008 |
A kinetic investigation, supported by theoretical calculations, of steric and ring strain effects on the oxidation of sulfides and sulfoxides by dimethyldioxirane in acetone P Hanson, RAAJ Hendrickx, JRL Smith New Journal of Chemistry 34 (1), 65-84, 2010 | 27 | 2010 |
Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators M Hemmerling, K Edman, M Lepistö, A Eriksson, S Ivanova, J Dahmén, ... Bioorganic & Medicinal Chemistry Letters 26 (23), 5741-5748, 2016 | 20 | 2016 |
Solid-state perturbation for solubility improvement: a proof of concept LE Briggner, R Hendrickx, L Kloo, J Rosdahl, PH Svensson ChemMedChem 6 (1), 60-62, 2011 | 18 | 2011 |
Effects of a selective glucocorticoid receptor modulator (AZD9567) versus prednisolone in healthy volunteers: two phase 1, single-blind, randomised controlled trials TH Myrbäck, S Prothon, K Edman, J Leander, M Hashemi, M Dearman, ... The Lancet Rheumatology 2 (1), e31-e41, 2020 | 17 | 2020 |
Characterization of selective and potent JAK1 inhibitors intended for the inhaled treatment of asthma M Nilsson, M Rhedin, R Hendrickx, S Berglund, A Piras, P Blomgran, ... Drug design, development and therapy, 2901-2917, 2023 | 11 | 2023 |
Kinetic studies on the oxidation of aryl methyl sulfides and sulfoxides by dimethyldioxirane; absolute rate constants and activation parameters for 4-nitrophenyl methyl sulfide … P Hanson, RAAJ Hendrickx, JRL Smith Organic & Biomolecular Chemistry 6 (4), 762-771, 2008 | 11 | 2008 |
The photoaddition of pyrroles to arylethenes and arylethynes M Austin, C Covell, A Gilbert, R Hendrickx Liebigs Annalen 1997 (5), 943-946, 1997 | 9 | 1997 |
Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata J Mattsson, E Israelsson, K Björhall, LF Yrlid, K Thörn, A Thorén, ... Skin Health and Disease 3 (3), e209, 2023 | 4 | 2023 |
Discovery of the potent and selective inhaled janus kinase 1 inhibitor AZD4604 and its preclinical characterization M Nilsson, K Berggren, S Berglund, S Cerboni, M Collins, G Dahl, ... Journal of Medicinal Chemistry 66 (19), 13400-13415, 2023 | 3 | 2023 |
SAT0245 Azd9567: a novel oral selective glucocorticoid receptor modulator, demonstrated to have an improved therapeutic ratio compared to prednisolone in pre-clinical studies … R Hendrickx, T Hegelund-Myrbäck, M Dearman, S Prothon, G Edenro, ... Annals of the Rheumatic Diseases 77 (Suppl 2), 984-985, 2018 | 2 | 2018 |
Identification of AZD9567, an anti-inflammatory glucocorticoid receptor modulator with improved side effect profile L Ripa, M Dearman, G Edenro, K Edman, R Hendrickx, M Lepisto, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | 1 | 2017 |
Investigating the efficacy of a NaV1. 7 channel blocker on airway sensory nerve activation and cough SJ Bonvini, F Shala, J Adcock, M Wortley, R Gopalakrishnan, S Francis, ... European Respiratory Journal 62 (suppl 67), 2023 | | 2023 |
Profiling the impact of two JAK inhibitors in a pre-clinical model of allergic asthma J Pinkerton, B Dekkak, D Zervas, T Markou, A Borde, A Cavallin, ... European Respiratory Journal 56 (suppl 64), 2020 | | 2020 |
SAT0251 Selective glucocorticoid receptor modulator shows potent anti-inflammatory effect with improved metabolic profile in a phase i study supported by in vitro data TH Myrbäck, S Prothon, M Dearman, G Edenro, J Leander, M Hashemi, ... Annals of the Rheumatic Diseases 77 (Suppl 2), 987-987, 2018 | | 2018 |
Next generation glucocorticoid receptor modulators K Edman, G Belfield, M Dearman, G Edenro, S Geschwindner, ... Endocrine Abstracts 54, 2018 | | 2018 |