| Model-assisted design of experiments as a concept for knowledge-based bioprocess development J Möller, KB Kuchemüller, T Steinmetz, KS Koopmann, R Pörtner Bioprocess and biosystems engineering 42, 867-882, 2019 | 78 | 2019 |
| Model-based tools for optimal experiments in bioprocess engineering V Abt, T Barz, MN Cruz-Bournazou, C Herwig, P Kroll, J Möller, R Pörtner, ... Current opinion in chemical engineering 22, 244-252, 2018 | 73 | 2018 |
| Model uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processes J Möller, TH Rodríguez, J Müller, L Arndt, KB Kuchemüller, B Frahm, ... Computers & chemical engineering 134, 106693, 2020 | 37 | 2020 |
| Digital twins C Herwig, R Pörtner, J Möller Springer, 2021 | 30 | 2021 |
| Digital twins for tissue culture techniques—concepts, expectations, and state of the art J Möller, R Pörtner Processes 9 (3), 447, 2021 | 29 | 2021 |
| Model‐based identification of cell‐cycle‐dependent metabolism and putative autocrine effects in antibody producing CHO cell culture J Möller, K Korte, R Pörtner, AP Zeng, U Jandt Biotechnology and bioengineering 115 (12), 2996-3008, 2018 | 24 | 2018 |
| Digital Twins: tools and concepts for smart biomanufacturing C Herwig, R Pörtner, J Möller Springer International Publishing, 2021 | 21 | 2021 |
| Model-assisted DoE software: optimization of growth and biocatalysis in Saccharomyces cerevisiae bioprocesses A Moser, KB Kuchemüller, S Deppe, T Hernández Rodríguez, B Frahm, ... Bioprocess and biosystems engineering 44, 683-700, 2021 | 20 | 2021 |
| Model-based design of process strategies for cell culture bioprocesses: state of the art and new perspectives J Möller, R Pörtner New insights into cell culture technology, 157-172, 2017 | 20 | 2017 |
| Process‐induced cell cycle oscillations in CHO cultures: Online monitoring and model‐based investigation J Möller, K Bhat, K Riecken, R Pörtner, AP Zeng, U Jandt Biotechnology and bioengineering 116 (11), 2931-2943, 2019 | 19 | 2019 |
| Digital twins and their role in model-assisted design of experiments KB Kuchemüller, R Pörtner, J Möller Digital Twins: Applications to the Design and Optimization of Bioprocesses …, 2021 | 16 | 2021 |
| Model‐based workflow for scale‐up of process strategies developed in miniaturized bioreactor systems L Arndt, V Wiegmann, KB Kuchemüller, F Baganz, R Pörtner, J Möller Biotechnology progress 37 (3), e3122, 2021 | 13 | 2021 |
| Efficient optimization of process strategies with model-assisted design of experiments KB Kuchemüller, R Pörtner, J Möller Animal Cell Biotechnology: Methods and Protocols, 235-249, 2020 | 13 | 2020 |
| New insights from locally resolved hydrodynamics in stirred cell culture reactors F Freiberger, J Budde, E Ateş, M Schlüter, R Pörtner, J Möller Processes 10 (1), 107, 2022 | 11 | 2022 |
| Comparison of mechanistic and hybrid modeling approaches for characterization of a CHO cultivation process: Requirements, pitfalls and solution paths B Bayer, M Duerkop, R Pörtner, J Möller Biotechnology journal 18 (1), 2200381, 2023 | 10 | 2023 |
| Estimation of process model parameters S Deppe, B Frahm, VC Hass, T Hernández Rodríguez, KB Kuchemüller, ... Animal Cell Biotechnology: Methods and Protocols, 213-234, 2020 | 9 | 2020 |
| Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells J Möller, K Bhat, L Guhl, R Pörtner, U Jandt, AP Zeng Engineering in life sciences 21 (3-4), 100-114, 2021 | 7 | 2021 |
| Quantification of the dynamics of population heterogeneities in CHO cultures with stably integrated fluorescent markers J Möller, M Rosenberg, K Riecken, R Pörtner, AP Zeng, U Jandt Analytical and bioanalytical chemistry 412, 2065-2080, 2020 | 5 | 2020 |
| Model-based DoE for feed batch cultivation of a CHO cell line J Möllerl, R Eibl, D Eibl, R Pörtner BMC Proceedings 9 (Suppl 9), P42, 2015 | 5 | 2015 |
| Model‐assisted DoE–A concept study for cell culture process development J Möller, K Kuchemüller, R Pörtner Chemie Ingenieur Technik 90 (9), 1235-1235, 2018 | 4 | 2018 |
Pörtner RalfHamburg University of TechnologyVerified email at tuhh.de
