| δ Opioidmimetic Antagonists: Prototypes for Designing a New Generation of Ultraselective Opioid Peptides S Salvadori, M Attila, G Balboni, C Bianchi, SD Bryant, O Crescenzi, ... Molecular medicine 1, 678-689, 1995 | 154 | 1995 |
| Evaluation of the Dmt− tic pharmacophore: conversion of a potent δ-opioid receptor antagonist into a potent δ agonist and ligands with mixed properties G Balboni, R Guerrini, S Salvadori, C Bianchi, D Rizzi, SD Bryant, ... Journal of medicinal chemistry 45 (3), 713-720, 2002 | 121 | 2002 |
| Dmt and opioid peptides: a potent alliance SD Bryant, Y Jinsmaa, S Salvadori, Y Okada, LH Lazarus Peptide Science 71 (2), 86-102, 2003 | 111 | 2003 |
| Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary δ opioid antagonist activity S Salvadori, G Balboni, R Guerrini, R Tomatis, C Bianchi, SD Bryant, ... Journal of medicinal chemistry 40 (19), 3100-3108, 1997 | 108 | 1997 |
| Potent δ-Opioid Receptor Agonists Containing the Dmt− Tic Pharmacophore G Balboni, S Salvadori, R Guerrini, L Negri, E Giannini, Y Jinsmaa, ... Journal of medicinal chemistry 45 (25), 5556-5563, 2002 | 101 | 2002 |
| What peptides these deltorphins be LH Lazarus, SD Bryant, PS Cooper, S Salvadori Progress in neurobiology 57 (4), 377-420, 1999 | 86 | 1999 |
| Molecular docking and 3D-pharmacophore modeling to study the interactions of chalcone derivatives with estrogen receptor alpha M Muchtaridi, HN Syahidah, A Subarnas, M Yusuf, SD Bryant, T Langer Pharmaceuticals 10 (4), 81, 2017 | 82 | 2017 |
| Further studies on the Dmt-Tic pharmacophore: hydrophobic substituents at the C-terminus endow δ antagonists to manifest μ agonism or μ antagonism S Salvadori, R Guerrini, G Balboni, C Bianchi, SD Bryant, PS Cooper, ... Journal of medicinal chemistry 42 (24), 5010-5019, 1999 | 79 | 1999 |
| Structural studies of [2′, 6′-dimethyl-L-tyrosine1] endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bond Y Okada, Y Fujita, T Motoyama, Y Tsuda, T Yokoi, T Li, Y Sasaki, A Ambo, ... Bioorganic & medicinal chemistry 11 (9), 1983-1994, 2003 | 71 | 2003 |
| New δ-opioid antagonists as pharmacological probes SD Bryant, S Salvadori, PS Cooper, LH Lazarus Trends in pharmacological sciences 19 (2), 42-46, 1998 | 70 | 1998 |
| Development of potent bifunctional endomorphin-2 analogues with mixed μ-/δ-opioid agonist and δ-opioid antagonist properties Y Fujita, Y Tsuda, T Li, T Motoyama, M Takahashi, Y Shimizu, T Yokoi, ... Journal of medicinal chemistry 47 (14), 3591-3599, 2004 | 66 | 2004 |
| Conversion of enkephalin and dermorphin into δ‐selective opioid antagonists by single‐residue substitution T Tancredi, S Salvadori, P Amodeo, D Picone, LH Lazarus, SD Bryant, ... European journal of biochemistry 224 (1), 241-247, 1994 | 64 | 1994 |
| Synthesis of stereoisomeric analogues of endomorphin-2, H-Tyr-Pro-Phe-Phe-NH2, and examination of their opioid receptor binding activities and solution conformation Y Okada, A Fukumizu, M Takahashi, Y Shimizu, Y Tsuda, T Yokoi, ... Biochemical and Biophysical Research Communications 276 (1), 7-11, 2000 | 63 | 2000 |
| Development of potent μ-opioid receptor ligands using unique tyrosine analogues of endomorphin-2 T Li, Y Fujita, Y Tsuda, A Miyazaki, A Ambo, Y Sasaki, Y Jinsmaa, ... Journal of medicinal chemistry 48 (2), 586-592, 2005 | 61 | 2005 |
| Design of δ-opioid peptide antagonists for emerging drug applications LH Lazarus, SD Bryant, PS Cooper, R Guerrini, G Balboni, S Salvadori Drug Discovery Today 3 (6), 284-294, 1998 | 58 | 1998 |
| Bifunctional [2‘,6‘-Dimethyl-l-tyrosine]endomorphin-2 Analogues Substituted at Position 3 with Alkylated Phenylalanine Derivatives Yield Potent Mixed μ-Agonist/δ … T Li, K Shiotani, A Miyazaki, Y Tsuda, A Ambo, Y Sasaki, Y Jinsmaa, ... Journal of medicinal chemistry 50 (12), 2753-2766, 2007 | 56 | 2007 |
| Oral Bioavailability of a New Class of μ-Opioid Receptor Agonists Containing 3,6-Bis[Dmt-NH(CH2)n]-2(1H)-pyrazinone with Central-Mediated Analgesia Y Jinsmaa, A Miyazaki, Y Fujita, T Li, Y Fujisawa, K Shiotani, Y Tsuda, ... Journal of medicinal chemistry 47 (10), 2599-2610, 2004 | 56 | 2004 |
| 6-N,N-Dimethylamino-2,3-naphthalimide: A New Environment-Sensitive Fluorescent Probe in δ- and μ-Selective Opioid Peptides ME Vázquez, JB Blanco, S Salvadori, C Trapella, R Argazzi, SD Bryant, ... Journal of medicinal chemistry 49 (12), 3653-3658, 2006 | 55 | 2006 |
| Endomorphins and related opioid peptides Y Okada, Y Tsuda, SD Bryant, LH Lazarust Academic Press 65, 257-279, 2002 | 55 | 2002 |
| Novel 2′, 6′-dimethyl-l-tyrosine-containing pyrazinone opioid mimetic μ-agonists with potent antinociceptive activity in mice Y Jinsmaa, Y Okada, Y Tsuda, K Shiotani, Y Sasaki, A Ambo, SD Bryant, ... Journal of Pharmacology and Experimental Therapeutics 309 (1), 432-438, 2004 | 54 | 2004 |
