Simona Cristea
Simona Cristea
Dana-Farber Cancer Institute, Harvard School of Public Health
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Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
M Karaayvaz, S Cristea, SM Gillespie, AP Patel, R Mylvaganam, CC Luo, ...
Nature communications 9 (1), 1-10, 2018
TiMEx: a waiting time model for mutually exclusive cancer alterations
S Constantinescu, E Szczurek, P Mohammadi, J Rahnenführer, ...
Bioinformatics 32 (7), 968-975, 2016
pathTiMEx: Joint Inference of Mutually Exclusive Cancer Pathways and Their Progression Dynamics
S Cristea, J Kuipers, N Beerenwinkel
Journal of Computational Biology 24 (6), 603-615, 2017
Chromosomal alterations and gene expression changes associated with the progression of leukoplakia to advanced gingivobuccal cancer
PG Bhosale, S Cristea, S Ambatipudi, RS Desai, R Kumar, A Patil, S Kane, ...
Translational oncology 10 (3), 396-409, 2017
Sulforaphane preconditioning sensitizes human colon cancer cells towards the bioreductive anticancer prodrug PR-104A
MM Erzinger, C Bovet, KM Hecht, S Senger, P Winiker, N Sobotzki, ...
PLoS One 11 (3), 2016
Transcriptomic responses of cancerous and noncancerous human colon cells to sulforaphane and selenium
S Constantinescu, K Hecht, N Sobotzki, MM Erzinger, C Bovet, JW Shay, ...
Chemical research in toxicology 27 (3), 377-386, 2014
Ectopic expression of Msx2 in mammalian myotubes recapitulates aspects of amphibian muscle dedifferentiation
A Yilmaz, R Engeler, S Constantinescu, KD Kokkaliaris, ...
Stem cell research 15 (3), 542-553, 2015
Graph-based decomposition of biochemical reaction networks into monotone subsystems
HM Kaltenbach, S Constantinescu, J Feigelman, J Stelling
International Workshop on Algorithms in Bioinformatics, 139-150, 2011
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments
M Janiszewska, DP Tabassum, Z Castaño, S Cristea, KN Yamamoto, ...
Nature cell biology 21 (7), 879-888, 2019
Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules
D Silverbush, S Cristea, G Yanovich-Arad, T Geiger, N Beerenwinkel, ...
Cell systems 8 (5), 456-466. e5, 2019
Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity
A Gyuris, J Navarrete-Perea, A Jo, S Cristea, S Zhou, K Fraser, Z Wei, ...
Cell reports 27 (13), 3972-3987. e6, 2019
Dissecting the mammary gland one cell at a time
S Cristea, K Polyak
Nature communications 9 (1), 1-3, 2018
Recurring Amplification at 11q22. 1-q22. 2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC
PG Bhosale, M Pandey, S Cristea, M Shah, A Patil, N Beerenwinkel, ...
Scientific reports 7 (1), 1-14, 2017
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ
L Ding, Y Su, A Fassl, K Hinohara, X Qiu, NW Harper, SJ Huh, ...
Nature communications 10 (1), 1-16, 2019
Principles of Systems Biology, No. 31
H Cho, B Berger, J Peng, C Galitzine, O Vitek, PMJ Beltran, IM Cristea, ...
Cell systems 7 (2), 133-135, 2018
Genomic determinants of lymph node metastasis and radioresistance in oral squamous cell carcinoma
PG Bhosale, M Pandey, M Shah, MB Mahimkar, S Cristea, ...
Proceedings of the forty second annual conference of Environmental Mutagen …, 2018
Computational studies in cancer progression and treatment
S Cristea
ETH Zurich, 2016
Computational Data Integration in Toxicogenomics
S Constantinescu, SJ Sturla, G Marra, B Wollscheid, N Beerenwinkel
Computational Systems Toxicology, 371-392, 2015
Impact of sulforaphane on cytotoxicity of bioreductive anticancer drug PR-104A in human colon cells
MM Erzinger, KM Hecht, A Uzozie, S Constantinescu, N Sobotzki, ...
Abstracts of Papers of the American Chemical Society 248, 11-TOXI, 2014
Monotone Modules Approximation
S Constantinescu
Eidgenössische Technische Hochschule Zürich, Department of Computer Science, 2011
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Artikelen 1–20