| Selective inhibition of BET bromodomains P Filippakopoulos, J Qi, S Picaud, Y Shen, WB Smith, O Fedorov, ... Nature 468 (7327), 1067-1073, 2010 | 4211 | 2010 |
| A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria A Mbengue, S Bhattacharjee, T Pandharkar, H Liu, G Estiu, RV Stahelin, ... Nature 520 (7549), 683-687, 2015 | 677 | 2015 |
| Quantum mechanical methods and the interpretation and prediction of pericyclic reaction mechanisms O Wiest, DC Montiel, KN Houk The Journal of Physical Chemistry A 101 (45), 8378-8388, 1997 | 262 | 1997 |
| Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases DF Wang, P Helquist, NL Wiech, O Wiest Journal of medicinal chemistry 48 (22), 6936-6947, 2005 | 260 | 2005 |
| Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts NH Pipalia, CC Cosner, A Huang, A Chatterjee, P Bourbon, N Farley, ... Proceedings of the National Academy of Sciences 108 (14), 5620-5625, 2011 | 249 | 2011 |
| Density functional theory isotope effects and activation energies for the Cope and Claisen rearrangements O Wiest, KA Black, KN Houk Journal of the American Chemical Society 116 (22), 10336-10337, 1994 | 221 | 1994 |
| Direct visible-light-excited asymmetric Lewis acid catalysis of intermolecular [2+ 2] photocycloadditions X Huang, TR Quinn, K Harms, RD Webster, L Zhang, O Wiest, E Meggers Journal of the American Chemical Society 139 (27), 9120-9123, 2017 | 207 | 2017 |
| Mechanism, reactivity, and selectivity in palladium-catalyzed redox-relay Heck arylations of alkenyl alcohols L Xu, MJ Hilton, X Zhang, PO Norrby, YD Wu, MS Sigman, O Wiest Journal of the American Chemical Society 136 (5), 1960-1967, 2014 | 201 | 2014 |
| Comparative Genome-Scale Metabolic Reconstruction and Flux Balance Analysis of Multiple Staphylococcus aureus Genomes Identify Novel Antimicrobial Drug … DS Lee, H Burd, J Liu, E Almaas, O Wiest, AL Barabási, ZN Oltvai, ... Journal of bacteriology 191 (12), 4015-4024, 2009 | 188 | 2009 |
| On the function of the 14 Å long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors DF Wang, O Wiest, P Helquist, HY Lan-Hargest, NL Wiech Journal of medicinal chemistry 47 (13), 3409-3417, 2004 | 186 | 2004 |
| Synergy of combining sonolysis and photocatalysis in the degradation and mineralization of chlorinated aromatic compounds J Peller, O Wiest, PV Kamat Environmental science & technology 37 (9), 1926-1932, 2003 | 163 | 2003 |
| Theoretical studies of mixed-valence transition metal complexes for molecular computing SB Braun-Sand, O Wiest The Journal of Physical Chemistry A 107 (2), 285-291, 2003 | 141 | 2003 |
| Hydroxyl radical's role in the remediation of a common herbicide, 2, 4-dichlorophenoxyacetic acid (2, 4-D) J Peller, O Wiest, PV Kamat The Journal of Physical Chemistry A 108 (50), 10925-10933, 2004 | 137 | 2004 |
| Structural origin of selectivity in class II-selective histone deacetylase inhibitors G Estiu, E Greenberg, CB Harrison, NP Kwiatkowski, R Mazitschek, ... Journal of medicinal chemistry 51 (10), 2898-2906, 2008 | 135 | 2008 |
| Sonolysis of 2,4-Dichlorophenoxyacetic Acid in Aqueous Solutions. Evidence for •OH-Radical-Mediated Degradation J Peller, O Wiest, PV Kamat The Journal of Physical Chemistry A 105 (13), 3176-3181, 2001 | 135 | 2001 |
| Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold AA Bowers, N West, TL Newkirk, AE Troutman-Youngman, SL Schreiber, ... Organic letters 11 (6), 1301-1304, 2009 | 133 | 2009 |
| Chiral hypervalent organo‐iodine (III) compounds UH Hirt, MFH Schuster, AN French, OG Wiest, T Wirth European Journal of Organic Chemistry 2001 (8), 1569-1579, 2001 | 133 | 2001 |
| Prediction of enantioselectivity in rhodium catalyzed hydrogenations PJ Donoghue, P Helquist, PO Norrby, O Wiest Journal of the American Chemical Society 131 (2), 410-411, 2009 | 131 | 2009 |
| Few-shot graph learning for molecular property prediction Z Guo, C Zhang, W Yu, J Herr, O Wiest, M Jiang, NV Chawla Proceedings of the web conference 2021, 2559-2567, 2021 | 130 | 2021 |
| Synthesis of primary aryl amines through a copper-assisted aromatic substitution reaction with sodium azide JT Markiewicz, O Wiest, P Helquist The Journal of Organic Chemistry 75 (14), 4887-4890, 2010 | 127 | 2010 |
Per-Ola NorrbyPrincipal Scientist, AstraZenecaEmail verificata su astrazeneca.com
