Weak affinity chromatography as a new approach for fragment screening in drug discovery MD Duong-Thi, E Meiby, M Bergström, T Fex, R Isaksson, S Ohlson Analytical biochemistry 414 (1), 138-146, 2011 | 93 | 2011 |
Design and synthesis of ligand efficient dual inhibitors of janus kinase (JAK) and histone deacetylase (HDAC) based on ruxolitinib and vorinostat L Yao, N Mustafa, EC Tan, A Poulsen, P Singh, MD Duong-Thi, JXT Lee, ... Journal of medicinal chemistry 60 (20), 8336-8357, 2017 | 89 | 2017 |
Identification of the benzodiazepines as a new class of antileishmanial agent RL Clark, KC Carter, AB Mullen, GD Coxon, G Owusu-Dapaah, ... Bioorganic & medicinal chemistry letters 17 (3), 624-627, 2007 | 65 | 2007 |
High-throughput fragment screening by affinity LC-MS MD Duong-Thi, M Bergström, T Fex, R Isaksson, S Ohlson Journal of Biomolecular Screening 18 (2), 160-171, 2013 | 43 | 2013 |
Fragment screening for drug leads by weak affinity chromatography (WAC-MS) S Ohlson, MD Duong-Thi Methods 146, 26-38, 2018 | 25 | 2018 |
Comparison of weak affinity chromatography and surface plasmon resonance in determining affinity of small molecules MD Duong-Thi, G Bergström, CF Mandenius, M Bergström, T Fex, ... Analytical biochemistry 461, 57-59, 2014 | 23 | 2014 |
Lipodisks integrated with weak affinity chromatography enable fragment screening of integral membrane proteins MD Duong-Thi, M Bergström, K Edwards, J Eriksson, S Ohlson, JTY Ying, ... Analyst 141 (3), 981-988, 2016 | 17 | 2016 |
Weak affinity chromatography for evaluation of stereoisomers in early drug discovery MD Duong-Thi, M Bergström, T Fex, S Svensson, S Ohlson, R Isaksson Journal of Biomolecular Screening 18 (6), 748-755, 2013 | 12 | 2013 |
Analysis of protein target interactions of synthetic mixtures by affinity-LC/MS P Singh, K Madhaiyan, MD Duong-Thi, BW Dymock, S Ohlson SLAS DISCOVERY: Advancing Life Sciences R&D 22 (4), 440-446, 2017 | 10 | 2017 |
Toward high‐throughput drug screening on a chip‐based parallel affinity separation platform S Ohlson, MD Duong‐Thi, M Bergström, T Fex, L Hansson, L Pedersen, ... Journal of separation science 33 (17‐18), 2575-2581, 2010 | 9 | 2010 |
Emerging technologies for fragment screening S Ohlson, MD Duong‐Thi Fragment‐based Drug Discovery Lessons and Outlook, 173-196, 2016 | 8 | 2016 |
Pharmaceutical modulation of the proteolytic profile of Transforming Growth Factor Beta induced protein (TGFBIp) offers a new avenue for treatment of TGFBI-corneal dystrophy A Venkatraman, MD Duong-Thi, K Pervushin, S Ohlson, JS Mehta Journal of Advanced Research 24, 529-543, 2020 | 6 | 2020 |
Weak Affinity Chromatography (WAC) S Ohlson, MD Duong‐Thi Applied Biophysics for Drug Discovery, 107-130, 2017 | 4 | 2017 |
Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages RLC M Dao Duong Thi, M Helen Grant, Alexander B Mullen, Justice N A Tettey ... J Pharm Pharmacol. 61 (3), 399-406, 2009 | 4 | 2009 |
Engineering a tunable micropattern‐array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ J Zhang, XY Rima, X Wang, LTH Nguyen, K Huntoon, Y Ma, PL Palacio, ... Journal of Extracellular Vesicles 12 (11), 12369, 2023 | 2 | 2023 |
Introducing weak affinity chromatography to drug discovery with focus on fragment screening MD Duong-Thi Linnaeus University Press, 2013 | 2 | 2013 |
Methods using weak interaction chromatography to separate and determine affinities of stereoisomers S Ohlson, MD Duong-Thi, E Meiby, R Isaksson, T Fex | | 2012 |
In Vitro Metabolism Studies of Two New Benzodiazepine-type Antileishmanial Agents MDD Thi | | 2006 |
WEAK AFFINITY CHROMATOGRAPHY (WAC) AS A NEW APPROACH FOR FRAGMENT–BASED DRUG DISCOVERY MD Duong-Thi | | |