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David W. Cescon
David W. Cescon
Medical Oncologist and Clinician Scientist, Princess Margaret Cancer Centre, University of Toronto
Email verificata su uhn.ca
Titolo
Citata da
Citata da
Anno
Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area
CM Booth, LM Matukas, GA Tomlinson, AR Rachlis, DB Rose, HA Dwosh, ...
Jama 289 (21), 2801-2809, 2003
18812003
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355 …
J Cortes, DW Cescon, HS Rugo, Z Nowecki, SA Im, MM Yusof, C Gallardo, ...
The Lancet 396 (10265), 1817-1828, 2020
12092020
Functional variants of OCTN cation transporter genes are associated with Crohn disease
VD Peltekova, RF Wintle, LA Rubin, CI Amos, Q Huang, X Gu, B Newman, ...
Nature genetics 36 (5), 471-475, 2004
9842004
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression
IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ...
Cancer cell 27 (2), 211-222, 2015
9152015
Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study
S Adams, P Schmid, HS Rugo, EP Winer, D Loirat, A Awada, DW Cescon, ...
Annals of Oncology 30 (3), 397-404, 2019
6992019
Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 study
S Adams, S Loi, D Toppmeyer, DW Cescon, M De Laurentiis, R Nanda, ...
Annals of Oncology 30 (3), 405-411, 2019
5362019
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 14432, 2017
4712017
Circulating tumor DNA and liquid biopsy in oncology
DW Cescon, SV Bratman, SM Chan, LL Siu
Nature Cancer 1 (3), 276-290, 2020
3712020
Pembrolizumab plus chemotherapy in advanced triple-negative breast cancer
J Cortes, HS Rugo, DW Cescon, SA Im, MM Yusof, C Gallardo, O Lipatov, ...
New England Journal of Medicine 387 (3), 217-226, 2022
3642022
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ...
Journal of Experimental Medicine 210 (8), 1529-1544, 2013
3022013
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2
S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ...
Cancer cell 30 (2), 337-348, 2016
2062016
KEYNOTE-355: Randomized, double-blind, phase III study of pembrolizumab+ chemotherapy versus placebo+ chemotherapy for previously untreated locally recurrent inoperable or …
J Cortes, DW Cescon, HS Rugo, Z Nowecki, SA Im, MM Yusof, C Gallardo, ...
Journal of Clinical Oncology 38 (15_suppl), 1000-1000, 2020
1982020
Relationship between tumor infiltrating lymphocyte (TIL) levels and response to pembrolizumab (pembro) in metastatic triple-negative breast cancer (mTNBC): results from KEYNOTE-086
S Loi, S Adams, P Schmid, J Cortés, DW Cescon, EP Winer, ...
Annals of Oncology 28, v608, 2017
1902017
Functional characterization of CFI-400945, a Polo-like kinase 4 inhibitor, as a potential anticancer agent
JM Mason, DCC Lin, X Wei, Y Che, Y Yao, R Kiarash, DW Cescon, ...
Cancer cell 26 (2), 163-176, 2014
1822014
Phase 2 study of pembrolizumab (pembro) monotherapy for previously treated metastatic triple-negative breast cancer (mTNBC): KEYNOTE-086 cohort A.
S Adams, P Schmid, HS Rugo, EP Winer, D Loirat, A Awada, DW Cescon, ...
Journal of Clinical Oncology 35 (15_suppl), 1008-1008, 2017
1692017
GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer
Q Wu, W Ba-Alawi, G Deblois, J Cruickshank, S Duan, E Lima-Fernandes, ...
Nature communications 11 (1), 4205, 2020
1672020
If we build it they will come: targeting the immune response to breast cancer
ME Gatti-Mays, JM Balko, SR Gameiro, HD Bear, S Prabhakaran, J Fukui, ...
NPJ breast cancer 5 (1), 37, 2019
1672019
Evolution of the randomized controlled trial in oncology over three decades
CM Booth, DW Cescon, L Wang, IF Tannock, MK Krzyzanowska
Journal of Clinical Oncology 26 (33), 5458, 2008
1662008
Toxicity of extended adjuvant therapy with aromatase inhibitors in early breast cancer: a systematic review and meta-analysis
H Goldvaser, TA Barnes, B Šeruga, DW Cescon, A Ocaña, D Ribnikar, ...
JNCI: Journal of the National Cancer Institute 110 (1), 31-39, 2018
1632018
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1
C Roux, SM Jafari, R Shinde, G Duncan, DW Cescon, J Silvester, MF Chu, ...
Proceedings of the National Academy of Sciences 116 (10), 4326-4335, 2019
1562019
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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