Jason H Yang
Jason H Yang
Rutgers New Jersey Medical School
Verified email at - Homepage
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Antibiotics induce redox-related physiological alterations as part of their lethality
DJ Dwyer*, PA Belenky*, JH Yang*, IC MacDonald, JD Martell, ...
Proceedings of the National Academy of Sciences 111 (20), E2100-E2109, 2014
Antibiotic efficacy is linked to bacterial cellular respiration
MA Lobritz*, P Belenky*, CBM Porter, A Gutierrez, JH Yang, EG Schwarz, ...
Proceedings of the National Academy of Sciences, 201509743, 2015
Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control
S Meylan, CBM Porter*, JH Yang*, P Belenky, A Gutierrez, MA Lobritz, ...
Cell Chemical Biology, 2017
A white-box machine learning approach for revealing antibiotic mechanisms of action
JH Yang, SN Wright, M Hamblin, D McCloskey, MA Alcantar, ...
Cell 177 (6), 1649-1661. e9, 2019
Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function
JH Yang*, P Bhargava*, D McCloskey, N Mao, BO Palsson, JJ Collins
Cell Host & Microbe, 2017
Regulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP
V Sample*, LM DiPilato*, JH Yang*, Q Ni, JJ Saucerman, J Zhang, ...
Nature chemical biology 8 (4), 375-382, 2012
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate
AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ...
Nature Microbiology 4 (12), 2109-2117, 2019
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
AJ Lopatkin, SC Bening, AL Manson, JM Stokes, MA Kohanski, ...
Science 371 (6531), eaba0862, 2021
Antibiotic efficacy—context matters
JH Yang*, SC Bening*, JJ Collins
Current Opinion in Microbiology 39, 73-80, 2017
Comparing McRoberts' and Rubin's maneuvers for initial management of shoulder dystocia: an objective evaluation
ED Gurewitsch, EJ Kim, JH Yang, KE Outland, MK McDonald, RH Allen
American journal of obstetrics and gynecology 192 (1), 153-160, 2005
Computational models reduce complexity and accelerate insight into cardiac signaling networks
JH Yang, JJ Saucerman
Circulation research 108 (1), 85-97, 2011
PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling
JH Yang, RK Polanowska-Grabowska, JS Smith, CW Shields IV, ...
Journal of molecular and cellular cardiology 66, 83-93, 2014
Phospholemman is a negative feed-forward regulator of Ca2+ in β-adrenergic signaling, accelerating β-adrenergic inotropy
JH Yang, JJ Saucerman
Journal of molecular and cellular cardiology 52 (5), 1048-1055, 2012
Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality
N Takahashi*, CC Gruber*, JH Yang, X Liu, D Braff, CN Yashaswini, ...
Proceedings of the National Academy of Sciences, 201707466, 2017
Simulating complicated human birth for research and training
EJ Kim, RH Allen, JH Yang, MK McDonald, W Tam, ED Gurewitsch
The 26th Annual International Conference of the IEEE Engineering in Medicine …, 2004
Applications of machine learning to the problem of antimicrobial resistance: An emerging model for translational research
MN Anahtar, JH Yang, S Kanjilal
Journal of Clinical Microbiology, JCM. 01260-20, 2021
Systems analysis of small signaling modules relevant to eight human diseases
KF Benedict, F Mac Gabhann*, RK Amanfu*, AK Chavali*, ...
Annals of biomedical engineering 39 (2), 621-635, 2011
Growth and stress tolerance comprise independent metabolic strategies critical for Staphylococcus aureus infection
GL Kim, TA Hooven, J Norambuena, B Li, JM Boyd, JH Yang, D Parker
Mbio 12 (3), e00814-21, 2021
Digital Insights Into Nucleotide Metabolism and Antibiotic Treatment Failure
AJ Lopatkin*, JH Yang*
Frontiers in Digital Health 3 (583468), 1-12, 2021
Facing the Upcoming of Multidrug-Resistant and Extensively Drug-Resistant Bacteria: Novel Antimicrobial Therapies (NATs)
A León-Buitimea, JR Morones-Ramírez, JH Yang, R Peña-Miller
Frontiers in Bioengineering and Biotechnology 9, 636278, 2021
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