|Structural basis for autoinhibition of Notch|
WR Gordon, D Vardar-Ulu, G Histen, C Sanchez-Irizarry, JC Aster, ...
Nature structural & molecular biology 14 (4), 295, 2007
|The molecular logic of Notch signaling–a structural and biochemical perspective|
WR Gordon, KL Arnett, SC Blacklow
Journal of cell science 121 (19), 3109-3119, 2008
|Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3|
K Li, Y Li, W Wu, WR Gordon, DW Chang, M Lu, S Scoggin, T Fu, L Vien, ...
Journal of Biological Chemistry 283 (12), 8046-8054, 2008
|Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors|
M Aste-Amézaga, N Zhang, JE Lineberger, BA Arnold, TJ Toner, M Gu, ...
PloS one 5 (2), e9094, 2010
|Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL|
WR Gordon, M Roy, D Vardar-Ulu, M Garfinkel, MR Mansour, JC Aster, ...
Blood 113 (18), 4381-4390, 2009
|Mechanical allostery: evidence for a force requirement in the proteolytic activation of Notch|
WR Gordon, B Zimmerman, L He, LJ Miles, J Huang, K Tiyanont, ...
Developmental cell 33 (6), 729-736, 2015
|Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2|
WR Gordon, D Vardar-Ulu, S L'Heureux, T Ashworth, MJ Malecki, ...
PloS one 4 (8), e6613, 2009
|Gas-phase photochemistry of the photoactive yellow protein chromophore trans-p-coumaric acid|
WL Ryan, DJ Gordon, DH Levy
Journal of the American Chemical Society 124 (21), 6194-6201, 2002
|Increasing Cas9-mediated homology-directed repair efficiency through covalent tethering of DNA repair template|
EJ Aird, KN Lovendahl, AS Martin, RS Harris, WR Gordon
Communications biology 1 (1), 54, 2018
|Electronic Spectroscopy and Photoisomerization of trans-Urocanic Acid in a Supersonic Jet|
WL Ryan, DH Levy
Journal of the American Chemical Society 123 (5), 961-966, 2001
|Sequence-directed covalent protein–DNA linkages in a single step using HUH-tags|
KN Lovendahl, AN Hayward, WR Gordon
Journal of the American Chemical Society 139 (20), 7030-7035, 2017
|Acylation of α-aminoalkyl-copper and cuprate reagents with acid chlorides: Improved yields with soluble copper (I) salts|
RK Dieter, RR Sharma, W Ryan
Tetrahedron letters 38 (5), 783-786, 1997
|Total chemical synthesis of fully functional Photoactive Yellow Protein|
KSB Gordon WR, Bang D, Hoff WD
Bioorg Med Chem 21 (12), 3436-3442, 2013
|Functional negative regulatory domain sequences from human NOTCH1 and 2 and isolated LNR domains from human NOTCH1|
S Blacklow, D Vardar-Ulu, WR Gordon, C Sanchez-Irizarry, JC Aster
US Patent App. 11/803,705, 2008
|The Molecular Mechanism of Notch Activation|
KN Lovendahl, SC Blacklow, WR Gordon
Molecular Mechanisms of Notch Signaling, 47-58, 2018
|Application and evaluation of anti-Notch antibodies to modulate Notch signaling|
WR Gordon, JC Aster
Notch Signaling, 323-333, 2014
|Excitation-Wavelength-Dependent Photocycle Initiation Dynamics Resolve Heterogeneity in the Photoactive Yellow Protein from Halorhodospira halophila|
LT Mix, EC Carroll, D Morozov, J Pan, WR Gordon, A Philip, J Fuzell, ...
Biochemistry 57 (11), 1733-1747, 2018
|Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors|
BR Webber, C Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ...
Nature communications 10 (1), 1-10, 2019
|SNAPS: A toolkit for studying cell surface shedding of diverse transmembrane receptors|
AN Hayward, EJ Aird, WR Gordon
bioRxiv, 436592, 2018
|Dystroglycan proteolysis is conformationally-regulated and disrupted by disease-associated mutations|
AN Hayward, WR Gordon
bioRxiv, 279315, 2018