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Kira M. Holmström
Kira M. Holmström
Head of Biomarker Research, Herantis Pharma Plc
Email verificata su herantis.com
Titolo
Citata da
Citata da
Anno
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
S Geisler, KM Holmström, D Skujat, FC Fiesel, OC Rothfuss, PJ Kahle, ...
Nature cell biology 12 (2), 119-131, 2010
30102010
Cellular mechanisms and physiological consequences of redox-dependent signalling
KM Holmström, T Finkel
Nature reviews Molecular cell biology 15 (6), 411-421, 2014
20642014
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
N Exner, B Treske, D Paquet, K Holmström, C Schiesling, S Gispert, ...
Journal of Neuroscience 27 (45), 12413-12418, 2007
6192007
Measuring in vivo mitophagy
N Sun, J Yun, J Liu, D Malide, C Liu, II Rovira, KM Holmström, ...
Molecular cell 60 (4), 685-696, 2015
6052015
Nrf2 regulates ROS production by mitochondria and NADPH oxidase
S Kovac, PR Angelova, KM Holmström, Y Zhang, AT Dinkova-Kostova, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 794-801, 2015
5802015
Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
KM Holmström, L Baird, Y Zhang, I Hargreaves, A Chalasani, JM Land, ...
Biology open 2 (8), 761-770, 2013
4372013
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
S Geisler, KM Holmström, A Treis, D Skujat, SS Weber, FC Fiesel, ...
Autophagy 6 (7), 871-878, 2010
3652010
The multifaceted role of Nrf2 in mitochondrial function
KM Holmström, RV Kostov, AT Dinkova-Kostova
Current opinion in toxicology 1, 80-91, 2016
3382016
Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesis
G Charlesworth, V Plagnol, KM Holmström, J Bras, UM Sheerin, E Preza, ...
The American Journal of Human Genetics 91 (6), 1041-1050, 2012
2862012
The ins and outs of mitochondrial calcium
T Finkel, S Menazza, KM Holmström, RJ Parks, J Liu, J Sun, J Liu, X Pan, ...
Circulation research 116 (11), 1810-1819, 2015
2652015
MICU1 serves as a molecular gatekeeper to prevent in vivo mitochondrial calcium overload
JC Liu, J Liu, KM Holmström, S Menazza, RJ Parks, MM Fergusson, ...
Cell reports 16 (6), 1561-1573, 2016
2072016
Signalling properties of inorganic polyphosphate in the mammalian brain
KM Holmström, N Marina, AY Baev, NW Wood, AV Gourine, AY Abramov
Nature communications 4 (1), 1362, 2013
1552013
Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter
KM Holmström, X Pan, JC Liu, S Menazza, J Liu, TT Nguyen, H Pan, ...
Journal of molecular and cellular cardiology 85, 178-182, 2015
1302015
Dopamine protects neurons against glutamate-induced excitotoxicity
A Vaarmann, S Kovac, KM Holmström, S Gandhi, AY Abramov
Cell death & disease 4 (1), e455-e455, 2013
1192013
Unresolved questions from the analysis of mice lacking MCU expression
E Murphy, X Pan, T Nguyen, J Liu, KM Holmström, T Finkel
Biochemical and biophysical research communications 449 (4), 384-385, 2014
1152014
Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage
P Narayan, KM Holmström, DH Kim, DJ Whitcomb, MR Wilson, ...
Biochemistry 53 (15), 2442-2453, 2014
1042014
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1
N Kieper, KM Holmström, D Ciceri, FC Fiesel, H Wolburg, E Ziviani, ...
Experimental cell research 316 (7), 1213-1224, 2010
812010
The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics
AT Dinkova-Kostova, L Baird, KM Holmström, CJ Meyer, AY Abramov
Biochemical society transactions 43 (4), 602-610, 2015
792015
Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter
RJ Parks, S Menazza, KM Holmström, G Amanakis, M Fergusson, H Ma, ...
Cardiovascular research 115 (2), 385-394, 2019
682019
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology
M Szibor, PK Dhandapani, E Dufour, KM Holmström, Y Zhuang, I Salwig, ...
Disease models & mechanisms 10 (2), 163-171, 2017
672017
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20