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| Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer MD Ritchie, LW Hahn, N Roodi, LR Bailey, WD Dupont, FF Parl, JH Moore The American Journal of Human Genetics 69 (1), 138-147, 2001 | 1898 | 2001 |
| Estimation of the warfarin dose with clinical and pharmacogenetic data International Warfarin Pharmacogenetics Consortium New England Journal of Medicine 360 (8), 753-764, 2009 | 1437 | 2009 |
| Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173, 2014 | 1219 | 2014 |
| Multifactor dimensionality reduction software for detecting gene–gene and gene–environment interactions LW Hahn, MD Ritchie, JH Moore Bioinformatics 19 (3), 376-382, 2003 | 1139 | 2003 |
| New genetic loci link adipose and insulin biology to body fat distribution D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ... Nature 518 (7538), 187, 2015 | 757 | 2015 |
| Genetic determinants of response to warfarin during initial anticoagulation UI Schwarz, MD Ritchie, Y Bradford, C Li, SM Dudek, A Frye-Anderson, ... New England Journal of Medicine 358 (10), 999-1008, 2008 | 672 | 2008 |
| PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations JC Denny, MD Ritchie, MA Basford, JM Pulley, L Bastarache, ... Bioinformatics 26 (9), 1205-1210, 2010 | 589 | 2010 |
| Power of multifactor dimensionality reduction for detecting gene‐gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity MD Ritchie, LW Hahn, JH Moore Genetic Epidemiology: The Official Publication of the International Genetic …, 2003 | 573 | 2003 |
| Methods of integrating data to uncover genotype–phenotype interactions MD Ritchie, ER Holzinger, R Li, SA Pendergrass, D Kim Nature Reviews Genetics 16 (2), 85-97, 2015 | 559 | 2015 |
| Mechanisms of thyroid hormone action GA Brent The Journal of clinical investigation 122 (9), 3035-3043, 2012 | 541 | 2012 |
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| Meta-analysis identifies six new susceptibility loci for atrial fibrillation PT Ellinor, KL Lunetta, CM Albert, NL Glazer, MD Ritchie, AV Smith, ... Nature genetics 44 (6), 670, 2012 | 476 | 2012 |
| Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data JC Denny, L Bastarache, MD Ritchie, RJ Carroll, R Zink, JD Mosley, ... Nature biotechnology 31 (12), 1102, 2013 | 472 | 2013 |
| A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose GM Cooper, JA Johnson, TY Langaee, H Feng, IB Stanaway, UI Schwarz, ... Blood 112 (4), 1022-1027, 2008 | 438 | 2008 |
| Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra-and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African … H Takahashi, GR Wilkinson, EA Nutescu, T Morita, MD Ritchie, ... Pharmacogenetics and genomics 16 (2), 101-110, 2006 | 436 | 2006 |
| Renin-angiotensin system gene polymorphisms and atrial fibrillation CT Tsai, LP Lai, JL Lin, FT Chiang, JJ Hwang, MD Ritchie, JH Moore, ... Circulation 109 (13), 1640-1646, 2004 | 435 | 2004 |
| The electronic medical records and genomics (eMERGE) network: past, present, and future O Gottesman, H Kuivaniemi, G Tromp, WA Faucett, R Li, TA Manolio, ... Genetics in Medicine 15 (10), 761, 2013 | 342 | 2013 |
| A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction DR Velez, BC White, AA Motsinger, WS Bush, MD Ritchie, SM Williams, ... Genetic Epidemiology: The Official Publication of the International Genetic …, 2007 | 335 | 2007 |
| Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism DQ Ma, PL Whitehead, MM Menold, ER Martin, AE Ashley-Koch, H Mei, ... The American Journal of Human Genetics 77 (3), 377-388, 2005 | 331 | 2005 |
