Segui
Linda Z. Penn
Linda Z. Penn
Senior Scientist, Princess Margaret Cancer Centre, Toronto, Ontario Canada
Email verificata su uhnresearch.ca - Home page
Titolo
Citata da
Citata da
Anno
Induction of apoptosis in fibroblasts by c-myc protein
GI Evan, AH Wyllie, CS Gilbert, TD Littlewood, H Land, M Brooks, ...
Cell 69 (1), 119-128, 1992
40271992
Reflecting on 25 years with MYC
N Meyer, LZ Penn
Nature Reviews Cancer 8 (12), 976-990, 2008
18802008
HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis
WWL Wong, J Dimitroulakos, MD Minden, LZ Penn
Leukemia 16 (4), 508-519, 2002
7022002
The myc oncogene: MarvelouslY complex
SK Oster, CSW Ho, EL Soucie, LZ Penn
Academic Press 84, 81-154, 2002
6152002
The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis
D Barsyte-Lovejoy, SK Lau, PC Boutros, F Khosravi, I Jurisica, IL Andrulis, ...
Cancer research 66 (10), 5330-5337, 2006
5622006
The interplay between cell signalling and the mevalonate pathway in cancer
PJ Mullen, R Yu, J Longo, MC Archer, LZ Penn
Nature Reviews Cancer 16 (11), 718-731, 2016
5442016
The molecular role of Myc in growth and transformation: recent discoveries lead to new insights
LM Facchini, LZ Penn
The FASEB Journal 12 (9), 633-651, 1998
5371998
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis
MG Annis, EL Soucie, PJ Dlugosz, JA Cruz‐Aguado, LZ Penn, B Leber, ...
The EMBO journal 24 (12), 2096-2103, 2005
4652005
Dysregulation of the mevalonate pathway promotes transformation
JW Clendening, A Pandyra, PC Boutros, SE Ghamrasni, F Khosravi, ...
Proceedings of the National Academy of Sciences 107 (34), 15051-15056, 2010
4332010
Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.
W Zhu, A Cowie, GW Wasfy, LZ Penn, B Leber, DW Andrews
The EMBO journal 15 (16), 4130-4141, 1996
4281996
MYC deregulation in primary human cancers
M Kalkat, J De Melo, KA Hickman, C Lourenco, C Redel, D Resetca, ...
Genes 8 (6), 151, 2017
3592017
Three-gene prognostic classifier for early-stage non–small-cell lung cancer
SK Lau, PC Boutros, M Pintilie, FH Blackhall, CQ Zhu, D Strumpf, ...
Journal of Clinical Oncology 25 (35), 5562-5569, 2007
3142007
AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress
S Sriskanthadevan, DV Jeyaraju, TE Chung, S Prabha, W Xu, M Skrtic, ...
Blood, The Journal of the American Society of Hematology 125 (13), 2120-2130, 2015
3082015
Rapamycin Enhances Apoptosis and Increases Sensitivity to Cisplatin in Vitro
Y Shi, A Frankel, LG Radvanyi, LZ Penn, RG Miller, GB Mills
Cancer research 55 (9), 1982-1988, 1995
2891995
Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues
ABY Hui, W Shi, PC Boutros, N Miller, M Pintilie, T Fyles, D McCready, ...
Laboratory investigation 89 (5), 597-606, 2009
2842009
Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: a potential therapeutic approach
J Dimitroulakos, D Nohynek, KL Backway, DW Hedley, H Yeger, ...
Blood, The Journal of the American Society of Hematology 93 (4), 1308-1318, 1999
2821999
Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis
J Wu, WWL Wong, F Khosravi, MD Minden, LZ Penn
Cancer research 64 (18), 6461-6468, 2004
2652004
Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry
YM Janumyan, CG Sansam, A Chattopadhyay, N Cheng, EL Soucie, ...
The EMBO journal 22 (20), 5459-5470, 2003
2582003
Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells
Z Xia, MM Tan, W Wei-Lynn Wong, J Dimitroulakos, MD Minden, LZ Penn
Leukemia 15 (9), 1398-1407, 2001
2532001
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression
DYL Mao, JD Watson, PS Yan, D Barsyte-Lovejoy, F Khosravi, ...
Current Biology 13 (10), 882-886, 2003
2452003
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20