| Stroke and the immune system: from pathophysiology to new therapeutic strategies R Macrez, C Ali, O Toutirais, B Le Mauff, G Defer, U Dirnagl, D Vivien The Lancet Neurology 10 (5), 471-480, 2011 | 595 | 2011 |
| Mouse model of in situ thromboembolic stroke and reperfusion C Orset, R Macrez, AR Young, D Panthou, E Angles-Cano, E Maubert, ... Stroke 38 (10), 2771-2778, 2007 | 243 | 2007 |
| Therapeutic benefits from nanoparticles: the potential significance of nanoscience in diseases with compromise to the blood brain barrier S Krol, R Macrez, F Docagne, G Defer, S Laurent, M Rahman, ... Chemical reviews 113 (3), 1877-1903, 2013 | 212 | 2013 |
| Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities R Macrez, PK Stys, D Vivien, SA Lipton, F Docagne The Lancet Neurology 15 (10), 1089-1102, 2016 | 143 | 2016 |
| Tissue plasminogen activator prevents white matter damage following stroke F Correa, M Gauberti, J Parcq, R Macrez, Y Hommet, P Obiang, ... Journal of Experimental Medicine 208 (6), 1229-1242, 2011 | 94 | 2011 |
| Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin N Lebeurrier, S Launay, R Macrez, E Maubert, H Legros, A Leclerc, ... Journal of Cell Science 121 (20), 3357-3365, 2008 | 85 | 2008 |
| Antibodies Preventing the Interaction of Tissue-Type Plasminogen Activator With N-Methyl-d-Aspartate Receptors Reduce Stroke Damages and Extend the … R Macrez, P Obiang, M Gauberti, B Roussel, A Baron, J Parcq, F Cassé, ... Stroke 42 (8), 2315-2322, 2011 | 84 | 2011 |
| Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders A Montagne, M Gauberti, R Macrez, A Jullienne, A Briens, JS Raynaud, ... Neuroimage 63 (2), 760-770, 2012 | 80 | 2012 |
| Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity J Parcq, T Bertrand, A Montagne, AF Baron, R Macrez, JM Billard, ... Cell Death & Differentiation 19 (12), 1983-1991, 2012 | 67 | 2012 |
| Functional Occurrence of the Interaction of Tissue Plasminogen Activator With the NR1 Subunit of N-Methyl-d-Aspartate Receptors During Stroke R Macrez, L Bezin, B Le Mauff, C Ali, D Vivien Stroke 41 (12), 2950-2955, 2010 | 58 | 2010 |
| The story of an exceptional serine protease, tissue-type plasminogen activator (tPA) M Hébert, F Lesept, D Vivien, R Macrez Revue neurologique 172 (3), 186-197, 2016 | 56 | 2016 |
| Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors F Lesept, A Chevilley, J Jezequel, L Ladépêche, R Macrez, M Aimable, ... Cell death & disease 7 (11), e2466-e2466, 2016 | 50 | 2016 |
| Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis R Macrez, MC Ortega, I Bardou, A Mehra, A Fournier, SMA Van der Pol, ... Brain 139 (9), 2406-2419, 2016 | 49 | 2016 |
| Nonionotropic action of endothelial NMDA receptors on blood–brain barrier permeability via Rho/ROCK-mediated phosphorylation of myosin A Mehra, S Guérit, R Macrez, F Gosselet, E Sevin, H Lebas, E Maubert, ... Journal of Neuroscience 40 (8), 1778-1787, 2020 | 48 | 2020 |
| Prediction of disease activity in models of multiple sclerosis by molecular magnetic resonance imaging of P-selectin AP Fournier, A Quenault, S Martinez de Lizarrondo, M Gauberti, G Defer, ... Proceedings of the National Academy of Sciences 114 (23), 6116-6121, 2017 | 48 | 2017 |
| Autoimmune encephalitis mediated by B-cell response against N-methyl-d-aspartate receptor I Wagnon, P Hélie, I Bardou, C Regnauld, L Lesec, J Leprince, M Naveau, ... Brain 143 (10), 2957-2972, 2020 | 47 | 2020 |
| Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact BD Roussel, R Macrez, A Jullienne, V Agin, E Maubert, L Dauphinot, ... Brain 132 (8), 2219-2230, 2009 | 46 | 2009 |
| Efficacy of alteplase in a mouse model of acute ischemic stroke: a retrospective pooled analysis C Orset, B Haelewyn, SM Allan, S Ansar, F Campos, TH Cho, A Durand, ... Stroke 47 (5), 1312-1318, 2016 | 42 | 2016 |
| GluN2D subunit-containing NMDA receptors control tissue plasminogen activator-mediated spatial memory P Obiang, R Macrez, A Jullienne, T Bertrand, F Lesept, C Ali, E Maubert, ... Journal of Neuroscience 32 (37), 12726-12734, 2012 | 38 | 2012 |
| High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate VJ Henry, M Lecointre, V Laudenbach, C Ali, R Macrez, A Jullienne, ... Neurobiology of Disease 50, 201-208, 2013 | 31 | 2013 |
