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Sajish Mathew
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Early-onset colorectal cancer: initial clues and current views
LJ Hofseth, JR Hebert, A Chanda, H Chen, BL Love, MM Pena, ...
Nature reviews Gastroenterology & hepatology 17 (6), 352-364, 2020
3092020
A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol
M Sajish, P Schimmel
Nature 519 (7543), 370-373, 2015
1622015
Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling
M Sajish, Q Zhou, S Kishi, DM Valdez Jr, M Kapoor, M Guo, S Lee, S Kim, ...
Nature chemical biology 8 (6), 547-554, 2012
962012
A charge reversal differentiates (p) ppGpp synthesis by monofunctional and bifunctional Rel proteins
M Sajish, D Tiwari, D Rananaware, VK Nandicoori, B Prakash
Journal of biological chemistry 282 (48), 34977-34983, 2007
592007
The significance of EXDD and RXKD motif conservation in Rel proteins
M Sajish, S Kalayil, SK Verma, VK Nandicoori, B Prakash
Journal of biological chemistry 284 (14), 9115-9123, 2009
582009
E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides
N Jain, N Dhimole, AR Khan, D De, SK Tomar, M Sajish, D Dutta, ...
Biochemical and biophysical research communications 379 (2), 201-205, 2009
552009
Nicotinamide augments the anti-inflammatory properties of resveratrol through PARP1 activation
M Yanez, M Jhanji, K Murphy, RM Gower, M Sajish, E Jabbarzadeh
Scientific reports 9 (1), 10219, 2019
472019
Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy
D Blocquel, S Li, N Wei, H Daub, M Sajish, ML Erfurth, G Kooi, J Zhou, ...
Nucleic acids research 45 (13), 8091-8104, 2017
452017
Dopamine triggers CTCF-dependent morphological and genomic remodeling of astrocytes
A Galloway, A Adeluyi, B O'Donovan, ML Fisher, CN Rao, P Critchfield, ...
Journal of Neuroscience 38 (21), 4846-4858, 2018
362018
Towards resolving the enigma of the dichotomy of resveratrol: cis-and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation
M Jhanji, CN Rao, M Sajish
GeroScience, 1171–1200, 2021
212021
Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration
M Jhanji, CN Rao, JC Massey, MC Hope III, X Zhou, CD Keene, T Ma, ...
Nature Communications 13 (1), 3244, 2022
122022
Resveratrol Protects against Skin Inflammation through Inhibition of Mast Cell, Sphingosine Kinase-1, Stat3 and NF-κB p65 Signaling Activation in Mice
CD Carlucci, Y Hui, AP Chumanevich, PA Robida, JW Fuseler, M Sajish, ...
International Journal of Molecular Sciences 24 (7), 6707, 2023
62023
Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice
M Oza, W Becker, PM Gummadidala, T Dias, MH Omebeyinje, L Chen, ...
Scientific Reports 9 (1), 10520, 2019
52019
Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
O Saatci, M Cetin, M Uner, UM Tokat, I Chatzistamou, PG Ersan, ...
Nature Communications 14 (1), 6997, 2023
12023
Tau regulates Arc stability in neuronal dendrites via a proteasome-sensitive but ubiquitin-independent pathway
DW Yakout, A Shroff, W Wei, V Thaker, ZD Allen, M Sajish, TY Nazarko, ...
Journal of Biological Chemistry, 107237, 2024
2024
Targeting PDE4D reinstates toxic PARP trapping via cAMP-ROS-DNA damage axis and restores the efficacy of standard of care in treatment-refractory ER+ breast cancer
O Saatci, M Cetin, M Uner, UM Tokat, I Chatzistamou, E Montaudon, ...
Cancer Research 84 (6_Supplement), 563-563, 2024
2024
Abstract A008: Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
O Saatci, M Cetin, M Uner, UM Tokat, I Chatzistamou, PG Ersan, ...
Cancer Research 84 (1_Supplement), A008-A008, 2024
2024
Tyrosine Inhibits TyrRS-mediated DNA Repair and Induces Neuronal Oxidative DNA Damage
M Jhanji, C Nageswara Rao, X Zhou, D C Keene, T Ma, J Stewart, ...
https://www.researchsquare.com/article/rs-785404/v1, 2021
2021
Compositions and Methods Comprising Tyrosyl-tRNA Synthetases and Resveratrol Compounds
P Schimmel, S Mathew
US Patent WO/2016/069,716, 2016
2016
E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides
B Prakash, M Sajish, N Jain, SK Tomar, P Parrack, D Dutta, D De, ...
ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009
2009
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