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J H Sinclair
J H Sinclair
Verified email at cam.ac.uk
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Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells
J Taylor-Wiedeman, JGP Sissons, LK Borysiewicz, JH Sinclair
Journal of general virology 72 (9), 2059-2064, 1991
9521991
Latency and reactivation of human cytomegalovirus
J Sinclair, P Sissons
Journal of General Virology 87 (7), 1763-1779, 2006
6232006
Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers
MB Reeves, PA MacAry, PJ Lehner, JGP Sissons, JH Sinclair
Proceedings of the National Academy of Sciences 102 (11), 4140-4145, 2005
4792005
Detection of endogenous human cytomegalovirus in CD34+ bone marrow progenitors
M Mendelson, S Monard, P Sissons, J Sinclair
Journal of General Virology 77 (12), 3099-3102, 1996
4751996
Induction of endogenous human cytomegalovirus gene expression after differentiation of monocytes from healthy carriers
J Taylor-Wiedeman, P Sissons, J Sinclair
Journal of virology 68 (3), 1597-1604, 1994
3821994
Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by …
LK Borysiewicz, JK Hickling, S Graham, J Sinclair, MP Cranage, GL Smith, ...
The Journal of experimental medicine 168 (3), 919-931, 1988
3631988
Human cytomegalovirus: Latency and reactivation in the myeloid lineage
J Sinclair
Journal of clinical virology 41 (3), 180-185, 2008
3372008
Complex I binding by a virally encoded RNA regulates mitochondria-induced cell death
MB Reeves, AA Davies, BP McSharry, GW Wilkinson, JH Sinclair
Science 316 (5829), 1345-1348, 2007
3362007
Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro
F Goodrum, M Reeves, J Sinclair, K High, T Shenk
Blood, The Journal of the American Society of Hematology 110 (3), 937-945, 2007
3032007
Control of cytomegalovirus lytic gene expression by histone acetylation
JC Murphy, W Fischle, E Verdin, JH Sinclair
The EMBO journal, 2002
2832002
Human cytomegalovirus infection of the monocyte/macrophage lineage in bone marrow
EJ Minton, C Tysoe, JH Sinclair, JG Sissons
Journal of virology 68 (6), 4017-4021, 1994
2761994
Aspects of human cytomegalovirus latency and reactivation
M Reeves, J Sinclair
Human Cytomegalovirus, 297-313, 2008
2582008
The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts …
C Hagemeier, S Walker, R Caswell, T Kouzarides, J Sinclair
Journal of Virology 66 (7), 4452-4456, 1992
2321992
Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.
C Hagemeier, R Caswell, G Hayhurst, J Sinclair, T Kouzarides
The EMBO journal 13 (12), 2897-2903, 1994
2121994
Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter
DL Woodhall, IJ Groves, MB Reeves, G Wilkinson, JH Sinclair
Journal of Biological Chemistry 281 (49), 37652-37660, 2006
2102006
An in vitro model for the regulation of human cytomegalovirus latency and reactivation in dendritic cells by chromatin remodelling
MB Reeves, PJ Lehner, JGP Sissons, JH Sinclair
Journal of General Virology 86 (11), 2949-2954, 2005
2002005
Latent and persistent infections of monocytes and macrophages
J Sinclair, P Sissons
Intervirology 39 (5-6), 293-301, 1996
1981996
Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis
MR Wills, O Ashiru, MB Reeves, G Okecha, J Trowsdale, P Tomasec, ...
The Journal of Immunology 175 (11), 7457-7465, 2005
1962005
Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product.
GW Wilkinson, C Kelly, JH Sinclair, C Rickards
The Journal of general virology 79 (5), 1233-1245, 1998
1901998
The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and …
R Caswell, C Hagemeier, CJ Chiou, G Hayward, T Kouzarides, J Sinclair
Journal of General Virology 74 (12), 2691-2698, 1993
1721993
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