Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF PF Mercer, HV Woodcock, JD Eley, M Platé, MG Sulikowski, ... Thorax 71 (8), 701-711, 2016 | 202 | 2016 |
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ... Nature communications 10 (1), 6, 2019 | 160 | 2019 |
An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices MM Khan, D Poeckel, A Halavatyi, J Zukowska-Kasprzyk, F Stein, ... European Respiratory Journal 58 (1), 2021 | 24 | 2021 |
A high content, phenotypic ‘scar-in-a-jar’assay for rapid quantification of collagen fibrillogenesis using disease-derived pulmonary fibroblasts RB Good, JD Eley, E Gower, G Butt, AD Blanchard, AJ Fisher, ... BMC Biomedical Engineering 1, 1-10, 2019 | 19 | 2019 |
Omipalasib modulates extracellular matrix turnover in IPF patients: exploratory biomarker analysis from a phase I proof of mechanism study CB Nanthakumar, J Eley, Y Man, NS Gudmann, RC Chambers, ... A29. EMERGING CONCEPTS IN LUNG FIBROSIS, A7301-A7301, 2019 | 8 | 2019 |
Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ... Nature Communications 11 (1), 4680, 2020 | 3 | 2020 |
Investigating the role of mTOR signalling in mediating the pro-fibrotic effects of TGF-β1 J Eley UCL (University College London), 2018 | 1 | 2018 |
Multiomic and quantitative label-free microscopy-based analysis of ex vivo culture and TGFbeta1 stimulation of human precision-cut lung slices MM Khan, D Poeckel, A Halavatyi, F Stein, J Vappiani, DC Sevin, ... bioRxiv, 2019.12. 13.875963, 2019 | | 2019 |
LSC-2017-mTOR-mediated cap-dependent translation is essential for human lung myofibroblast differentiation and collagen I synthesis JD Eley, HV Woodcock, CB Nanthakumar, PF Mercer, RC Chambers European Respiratory Journal 50 (suppl 61), 2017 | | 2017 |
S51 MTOR regulates TGF-β induced pro-fibrotic gene expression in primary human lung fibroblasts HV Woodcock, JD Eley, C Nanthakumar, TM Maher, PF Mercer, ... Thorax 71 (Suppl 3), A31-A31, 2016 | | 2016 |
Cell intrinsic and environmental factors influencing human bronchial epithelial cell migration F Millar, K Gowers, R Hynds, J Eley, R Chambers, S Janes, A Giangreco European Respiratory Journal 48 (suppl 60), 2016 | | 2016 |
Rapamycin Insensitive MTOR Signalling Promotes TGF-β Induced Pro-Fibrotic Gene Expression In Human Lung Fibroblasts H Woodcock, J Eley, S Peace, C Nanthakumar, TM Maher, P Mercer, ... B62. THE BIOLOGY OF SCARRING. WHERE ARE WE NOW, A4163-A4163, 2016 | | 2016 |
B62 THE BIOLOGY OF SCARRING. WHERE ARE WE NOW: Rapamycin Insensitive Mtor Signalling Promotes Tgf-[Beta] Induced Pro-Fibrotic Gene Expression In Human Lung Fibroblasts H Woodcock, J Eley, S Peace, C Nanthakumar, TM Maher, P Mercer, ... American Journal of Respiratory and Critical Care Medicine 193, 1, 2016 | | 2016 |