Mario Milani
Mario Milani
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Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ...
Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O2 diffusion to the heme
M Milani, A Pesce, Y Ouellet, P Ascenzi, M Guertin, M Bolognesi
The EMBO journal 20 (15), 3902-3909, 2001
Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication
R Assenberg, E Mastrangelo, TS Walter, A Verma, M Milani, RJ Owens, ...
Journal of virology 83 (24), 12895-12906, 2009
Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins
M Milani, A Pesce, M Nardini, H Ouellet, Y Ouellet, S Dewilde, A Bocedi, ...
Journal of inorganic biochemistry 99 (1), 97-109, 2005
Heme-ligand tunneling in group I truncated hemoglobins
M Milani, A Pesce, Y Ouellet, S Dewilde, J Friedman, P Ascenzi, ...
Journal of Biological Chemistry 279 (20), 21520-21525, 2004
A TyrCD1/TrpG8 hydrogen bond network and a TyrB10—TyrCD1 covalent link shape the heme distal site of Mycobacterium tuberculosis hemoglobin O
M Milani, PY Savard, H Ouellet, P Ascenzi, M Guertin, M Bolognesi
Proceedings of the National Academy of Sciences 100 (10), 5766-5771, 2003
Ligand‐induced dynamical regulation of NO conversion in Mycobacterium tuberculosis truncated hemoglobin‐N
A Bidon‐Chanal, MA MartÝ, A Crespo, M Milani, M Orozco, M Bolognesi, ...
Proteins: Structure, Function, and Bioinformatics 64 (2), 457-464, 2006
Structure-based inhibition of Norovirus RNA-dependent RNA polymerases
E Mastrangelo, M Pezzullo, D Tarantino, R Petazzi, F Germani, D Kramer, ...
Journal of molecular biology 419 (3-4), 198-210, 2012
Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
E Mastrangelo, M Milani, M Bollati, B Selisko, F Peyrane, V Pandini, ...
Journal of molecular biology 372 (2), 444-455, 2007
FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation
M Milani, F Ciriello, S Baroni, V Pandini, G Canevari, M Bolognesi, ...
Journal of molecular biology 411 (2), 463-473, 2011
Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus
M Bollati, M Milani, E Mastrangelo, S Ricagno, G Tedeschi, S Nonnis, ...
Journal of molecular biology 385 (1), 140-152, 2009
Protein fold and structure in the truncated (2/2) globin family
M Nardini, A Pesce, M Milani, M Bolognesi
Gene 398 (1-2), 2-11, 2007
Targeting the BIR domains of inhibitor of apoptosis (IAP) proteins in cancer treatment
F Cossu, M Milani, E Mastrangelo, D Lecis
Computational and Structural Biotechnology Journal 17, 142-150, 2019
Cyanide Binding to Truncated Hemoglobins:  A Crystallographic and Kinetic Study,
M Milani, Y Ouellet, H Ouellet, M Guertin, A Boffi, G Antonini, A Bocedi, ...
Biochemistry 43 (18), 5213-5221, 2004
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2
F Cossu, E Mastrangelo, M Milani, G Sorrentino, D Lecis, D Delia, ...
Biochemical and biophysical research communications 378 (2), 162-167, 2009
Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition
M Milani, E Mastrangelo, M Bollati, B Selisko, E Decroly, M Bouvet, ...
Antiviral research 83 (1), 28-34, 2009
Glycine amidinotransferase (GATM), renal Fanconi syndrome, and kidney failure
M Reichold, ED Klootwijk, J Reinders, EA Otto, M Milani, C Broeker, ...
Journal of the American Society of Nephrology: JASN 29 (7), 1849, 2018
Mycobacterial truncated hemoglobins: from genes to functions
P Ascenzi, M Bolognesi, M Milani, M Guertin, P Visca
Gene 398 (1-2), 42-51, 2007
Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds
R Croci, M Pezzullo, D Tarantino, M Milani, SC Tsay, R Sureshbabu, ...
PloS one 9 (3), e91765, 2014
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