| TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD MA White, E Kim, A Duffy, R Adalbert, BU Phillips, OM Peters, ... Nature neuroscience 21 (4), 552-563, 2018 | 227 | 2018 |
| Intranasal delivery of mesenchymal stem cell-derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease M Losurdo, M Pedrazzoli, C D'Agostino, CA Elia, F Massenzio, E Lonati, ... Stem cells translational medicine 9 (9), 1068-1084, 2020 | 158 | 2020 |
| Multitarget drug discovery for Alzheimer's disease: triazinones as BACE‐1 and GSK‐3β inhibitors F Prati, A De Simone, P Bisignano, A Armirotti, M Summa, D Pizzirani, ... Angewandte Chemie 127 (5), 1598-1602, 2015 | 148 | 2015 |
| 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer’s Disease F Prati, A De Simone, A Armirotti, M Summa, D Pizzirani, R Scarpelli, ... ACS chemical neuroscience 6 (10), 1665-1682, 2015 | 70 | 2015 |
| Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation E Pena-Altamira, F Prati, F Massenzio, M Virgili, A Contestabile, ... Expert opinion on therapeutic targets 20 (5), 627-640, 2016 | 66 | 2016 |
| Nutritional and pharmacological strategies to regulate microglial polarization in cognitive aging and Alzheimer’s disease E Peña-Altamira, S Petralla, F Massenzio, M Virgili, ML Bolognesi, ... Frontiers in aging neuroscience 9, 175, 2017 | 46 | 2017 |
| Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose F Massenzio, E Peña-Altamira, S Petralla, M Virgili, G Zuccheri, A Miti, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (12 …, 2018 | 35 | 2018 |
| Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells E Profilo, LE Peña-Altamira, M Corricelli, A Castegna, A Danese, G Agrimi, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (6 …, 2017 | 28 | 2017 |
| Novel sustainable-by-design HDAC inhibitors for the treatment of Alzheimer’s disease LA Soares Romeiro, JL da Costa Nunes, C de Oliveira Miranda, ... ACS Medicinal Chemistry Letters 10 (4), 671-676, 2019 | 26 | 2019 |
| Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors LE Pena-Altamira, E Polazzi, P Giuliani, A Beraudi, F Massenzio, ... Neurochemistry international 115, 37-49, 2018 | 25 | 2018 |
| A focused library of psychotropic analogues with neuroprotective and neuroregenerative potential E Uliassi, LE Peña-Altamira, AV Morales, F Massenzio, S Petralla, ... ACS Chemical Neuroscience 10 (1), 279-294, 2018 | 19 | 2018 |
| Neuronal regulation of neuroprotective microglial apolipoprotein E secretion in rat in vitro models of brain pathophysiology E Polazzi, I Mengoni, E Peña-Altamira, F Massenzio, M Virgili, S Petralla, ... Journal of Neuropathology & Experimental Neurology 74 (8), 818-834, 2015 | 18 | 2015 |
| Epigenetics and communication mechanisms in microglia activation with a view on technological approaches S Petralla, F De Chirico, A Miti, O Tartagni, F Massenzio, E Poeta, M Virgili, ... Biomolecules 11 (2), 306, 2021 | 15 | 2021 |
| Deficiency of mitochondrial aspartate-glutamate carrier 1 leads to oligodendrocyte precursor cell proliferation defects both in vitro and in vivo S Petralla, LE Peña-Altamira, E Poeta, F Massenzio, M Virgili, SN Barile, ... International Journal of Molecular Sciences 20 (18), 4486, 2019 | 14 | 2019 |
| New models of Parkinson’s like neuroinflammation in human microglia clone 3: Activation profiles induced by INF-γ plus high glucose and mitochondrial inhibitors F De Chirico, E Poeta, G Babini, I Piccolino, B Monti, F Massenzio Frontiers in Cellular Neuroscience 16, 1038721, 2022 | 4 | 2022 |
| Riluzole–Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis C Albertini, A Salerno, S Atzeni, E Uliassi, F Massenzio, A Maruca, ... ACS Chemical Neuroscience 13 (15), 2252-2260, 2022 | 4 | 2022 |
| In vivo morphological alterations of TAMs during KCa3. 1 inhibition—by using in vivo two-photon time-lapse technology F Massenzio, M Cambiaghi, F Marchiotto, D Boriero, C Limatola, ... Frontiers in Cellular Neuroscience 16, 1002487, 2022 | 3 | 2022 |
| Targeted quantitative metabolic profiling of brain-derived cell cultures by semi-automated MEPS and LC-MS/MS M Protti, M Cirrincione, S Palano, E Poeta, G Babini, MC Magnifico, ... Journal of Pharmaceutical and Biomedical Analysis 236, 115757, 2023 | 2 | 2023 |
| Inhibiting glycogen synthase kinase 3 suppresses TDP-43-mediated neurotoxicity in a caspase-dependant manner MA White, F Massenzio, X Li, MP Coleman, SJ Barmada, J Sreedharan Biorxiv, 2021.02. 03.429569, 2021 | 2 | 2021 |
| Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate … E Poeta, S Petralla, G Babini, B Renzi, L Celauro, MC Magnifico, ... Frontiers in Cellular Neuroscience 15, 773709, 2022 | 1 | 2022 |
