| Evolution from a Natural Flavones Nucleus to Obtain 2-(4-Propoxyphenyl)quinoline Derivatives As Potent Inhibitors of the S. aureus NorA Efflux Pump S Sabatini, F Gosetto, G Manfroni, O Tabarrini, GW Kaatz, D Patel, ... Journal of medicinal chemistry 54 (16), 5722-5736, 2011 | 123 | 2011 |
| A broad anti-influenza hybrid small molecule that potently disrupts the interaction of polymerase acidic protein–basic protein 1 (PA-PB1) subunits S Massari, G Nannetti, J Desantis, G Muratore, S Sabatini, G Manfroni, ... Journal of Medicinal Chemistry 58 (9), 3830-3842, 2015 | 105 | 2015 |
| Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors S Sabatini, F Gosetto, S Serritella, G Manfroni, O Tabarrini, N Iraci, ... Journal of Medicinal Chemistry 55 (7), 3568-3572, 2012 | 105 | 2012 |
| Synthesis and anti-BVDV activity of acridones as new potential antiviral agents O Tabarrini, G Manfroni, A Fravolini, V Cecchetti, S Sabatini, E De Clercq, ... Journal of medicinal chemistry 49 (8), 2621-2627, 2006 | 103 | 2006 |
| Structure− activity relationship study on anti-HIV 6-desfluoroquinolones O Tabarrini, S Massari, D Daelemans, M Stevens, G Manfroni, S Sabatini, ... Journal of medicinal chemistry 51 (17), 5454-5458, 2008 | 88 | 2008 |
| Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus JP Brincat, E Carosati, S Sabatini, G Manfroni, A Fravolini, JL Raygada, ... Journal of medicinal chemistry 54 (1), 354-365, 2011 | 85 | 2011 |
| Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors A Astolfi, T Felicetti, N Iraci, G Manfroni, S Massari, D Pietrella, O Tabarrini, ... Journal of medicinal chemistry 60 (4), 1598-1604, 2017 | 71 | 2017 |
| Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity P Blasi, A Schoubben, G Traina, G Manfroni, L Barberini, PF Alberti, ... International journal of pharmaceutics 454 (1), 316-323, 2013 | 71 | 2013 |
| Studies on anti-HIV quinolones: new insights on the C-6 position S Massari, D Daelemans, G Manfroni, S Sabatini, O Tabarrini, ... Bioorganic & medicinal chemistry 17 (2), 667-674, 2009 | 66 | 2009 |
| Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor G Manfroni, J Paeshuyse, S Massari, S Zanoli, B Gatto, G Maga, ... Journal of medicinal chemistry 52 (10), 3354-3365, 2009 | 65 | 2009 |
| Structure modifications of 6-aminoquinolones with potent anti-HIV activity O Tabarrini, M Stevens, V Cecchetti, S Sabatini, M Dell'Uomo, G Manfroni, ... Journal of medicinal chemistry 47 (22), 5567-5578, 2004 | 65 | 2004 |
| Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly S Massari, G Nannetti, L Goracci, L Sancineto, G Muratore, S Sabatini, ... Journal of Medicinal Chemistry 56 (24), 10118-10131, 2013 | 64 | 2013 |
| Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor D Tarantino, R Cannalire, E Mastrangelo, R Croci, G Querat, ML Barreca, ... Antiviral research 134, 226-235, 2016 | 63 | 2016 |
| Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase G Manfroni, F Meschini, ML Barreca, P Leyssen, A Samuele, N Iraci, ... Bioorganic & medicinal chemistry 20 (2), 866-876, 2012 | 59 | 2012 |
| Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to … S Sabatini, F Gosetto, N Iraci, ML Barreca, S Massari, L Sancineto, ... Journal of medicinal chemistry 56 (12), 4975-4989, 2013 | 57 | 2013 |
| A journey around the medicinal chemistry of hepatitis C virus inhibitors targeting NS4B: from target to preclinical drug candidates R Cannalire, ML Barreca, G Manfroni, V Cecchetti Journal of medicinal chemistry 59 (1), 16-41, 2016 | 56 | 2016 |
| The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors G Manfroni, R Cannalire, ML Barreca, N Kaushik-Basu, P Leyssen, ... Journal of medicinal chemistry 57 (5), 1952-1963, 2014 | 55 | 2014 |
| Allosteric Inhibition of the Hepatitis C Virus NS5B Polymerase: In Silico Strategies for Drug Discovery and Development ML Barreca, N Iraci, G Manfroni, V Cecchetti Future Medicinal Chemistry 3 (8), 1027-1055, 2011 | 55 | 2011 |
| Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity J Desantis, G Nannetti, S Massari, ML Barreca, G Manfroni, V Cecchetti, ... European Journal of Medicinal Chemistry 138, 128-139, 2017 | 53 | 2017 |
| 2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction T Felicetti, R Cannalire, D Pietrella, G Latacz, A Lubelska, G Manfroni, ... Journal of medicinal chemistry 61 (17), 7827-7848, 2018 | 50 | 2018 |
