Rafael De Cabo
Rafael De Cabo
Other namesRafael DeCabo, Rafael d Cabo, Rafa de Cabo
Translational Gerontology Branch, National Institute on Aging
Verified email at
Cited by
Cited by
Resveratrol improves health and survival of mice on a high-calorie diet
JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ...
Nature 444 (7117), 337-342, 2006
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen, C Miller, KJ Bitterman, NR Wall, B Hekking, B Kessler, ...
science 305 (5682), 390-392, 2004
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ...
Cell metabolism 15 (5), 675-690, 2012
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ...
Science 339 (6116), 211-214, 2013
Metformin improves healthspan and lifespan in mice
A Martin-Montalvo, EM Mercken, SJ Mitchell, HH Palacios, PL Mote, ...
Nature communications 4 (1), 2192, 2013
Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
AP Gomes, NL Price, AJY Ling, JJ Moslehi, MK Montgomery, L Rajman, ...
Cell 155 (7), 1624-1638, 2013
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
KJ Pearson, JA Baur, KN Lewis, L Peshkin, NL Price, N Labinskyy, ...
Cell metabolism 8 (2), 157-168, 2008
Effects of intermittent fasting on health, aging, and disease
R De Cabo, MP Mattson
New England Journal of Medicine 381 (26), 2541-2551, 2019
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
JA Mattison, GS Roth, TM Beasley, EM Tilmont, AM Handy, RL Herbert, ...
Nature 489 (7415), 318-321, 2012
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
H Yang, T Yang, JA Baur, E Perez, T Matsui, JJ Carmona, DW Lamming, ...
Cell 130 (6), 1095-1107, 2007
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
RA Miller, DE Harrison, CM Astle, JA Baur, AR Boyd, R De Cabo, ...
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2011
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
RM Anson, Z Guo, R de Cabo, T Iyun, M Rios, A Hagepanos, DK Ingram, ...
Proceedings of the National Academy of Sciences 100 (10), 6216-6220, 2003
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
J Guevara-Aguirre, P Balasubramanian, M Guevara-Aguirre, M Wei, ...
Science translational medicine 3 (70), 70ra13-70ra13, 2011
Caloric restriction improves health and survival of rhesus monkeys
JA Mattison, RJ Colman, TM Beasley, DB Allison, JW Kemnitz, GS Roth, ...
Nature communications 8 (1), 14063, 2017
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ...
Science translational medicine 4 (124), 124ra27-124ra27, 2012
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
G López-Lluch, N Hunt, B Jones, M Zhu, H Jamieson, S Hilmer, ...
Proceedings of the National Academy of Sciences 103 (6), 1768-1773, 2006
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
R Firestein, G Blander, S Michan, P Oberdoerffer, S Ogino, J Campbell, ...
PloS one 3 (4), e2020, 2008
Mechanisms of vascular aging: new perspectives
Z Ungvari, G Kaley, R De Cabo, WE Sonntag, A Csiszar
Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2010
Interventions to slow aging in humans: are we ready?
VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ...
Aging cell 14 (4), 497-510, 2015
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
Z Ungvari, Z Bagi, A Feher, FA Recchia, WE Sonntag, K Pearson, ...
American Journal of Physiology-Heart and Circulatory Physiology 299 (1), H18-H24, 2010
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