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Brad Watmuff
Brad Watmuff
Postdoctoral Fellow, Massachusetts General Hospital
Email verificata su mgh.harvard.edu
Titolo
Citata da
Citata da
Anno
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
CM Sellgren, J Gracias, B Watmuff, JD Biag, JM Thanos, PB Whittredge, ...
Nature neuroscience 22 (3), 374-385, 2019
6262019
A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives
AL Goulburn, D Alden, RP Davis, SJ Micallef, ES Ng, QC Yu, SM Lim, ...
Stem cells 29 (3), 462-473, 2011
1232011
Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine
A Kathuria, K Lopez-Lengowski, B Watmuff, D McPhie, BM Cohen, ...
Translational psychiatry 9 (1), 321, 2019
582019
Lysine deacetylation by HDAC6 regulates the kinase activity of AKT in human neural progenitor cells
J Iaconelli, J Lalonde, B Watmuff, B Liu, R Mazitschek, SJ Haggarty, ...
ACS chemical biology 12 (8), 2139-2148, 2017
532017
Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells
B Watmuff, SS Berkovitch, JH Huang, J Iaconelli, S Toffel, R Karmacharya
Molecular and Cellular Neuroscience 73, 96-103, 2016
412016
In vitro maturation of dopaminergic neurons derived from mouse embryonic stem cells: implications for transplantation
B Watmuff, CW Pouton, JM Haynes
PLoS One 7 (2), e31999, 2012
322012
Human pluripotent stem cell derived midbrain PITX3eGFP/w neurons: a versatile tool for pharmacological screening and neurodegenerative modeling
B Watmuff, BJ Hartley, CPJ Hunt, SA Fabb, CW Pouton, JM Haynes
Frontiers in cellular neuroscience 9, 104, 2015
232015
Unbiased metabolite profiling of schizophrenia fibroblasts under stressful perturbations reveals dysregulation of plasmalogens and phosphatidylcholines
JH Huang, H Park, J Iaconelli, SS Berkovitch, B Watmuff, D McPhie, ...
Journal of proteome research 16 (2), 481-493, 2017
212017
Stem cell-derived neurons in the development of targeted treatment for schizophrenia and bipolar disorder
B Watmuff, B Liu, R Karmacharya
Pharmacogenomics 18 (5), 471-479, 2017
162017
Comparative transcriptomic analysis of cerebral organoids and cortical neuron cultures derived from human induced pluripotent stem cells
A Kathuria, K Lopez-Lengowski, B Watmuff, R Karmacharya
Stem Cells and Development 29 (21), 1370-1381, 2020
142020
Perturbational profiling of metabolites in patient fibroblasts implicates α-aminoadipate as a potential biomarker for bipolar disorder
JH Huang, SS Berkovitch, J Iaconelli, B Watmuff, H Park, ...
Complex Psychiatry 2 (2), 97-106, 2016
102016
Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophrenia
A Kathuria, K Lopez-Lengowski, B Watmuff, R Karmacharya
Genome Medicine 15 (1), 58, 2023
12023
In vitro Differentiation of Pluripotent Stem Cells towards either Forebrain GABAergic or Midbrain Dopaminergic Neurons
BJ Hartley, B Watmuff, CPJ Hunt, JM Haynes, CW Pouton
Neural Stem Cell Assays, 91-99, 2014
12014
Pluripotent stem cell-derived dopaminergic neurons as models of neurodegeneration
B Watmuff, BJ Hartley, CP Hunt, CW Pouton, JM Haynes
Future Neurology 8 (6), 649-661, 2013
12013
Dendritic Spine Differences in iPSC-Derived Cortical Neurons in Schizophrenia
A Kathuria, B Watmuff, K Lopez-Lengowski, D McPhie, B Cohen, ...
Biological Psychiatry 89 (9), S33-S34, 2021
2021
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
J Gracias, B Watmuff, J Biag, J Thanos, P Whittredge, T Fu, K Worringer, ...
GLIA 67, E325-E325, 2019
2019
S193. EX VIVO SIGNATURE OF PSYCHOSIS AND TREATMENT RESPONSE IN PATIENT-DERIVED NEURONS
R Karmacharya, B Watmuff, A Kathuria, B Liu
Schizophrenia Bulletin 44 (Suppl 1), S400, 2018
2018
Interrogating disease biology of bipolar disorder using patient-derived cells
R Karmacharya, B Watmuff, B Liu, A Kathuria
BIPOLAR DISORDERS 20, 9-9, 2018
2018
Increased microglial synapse elimination in patient-specific models of schizophrenia
CM Sellgren, J Gracias, B Watmuff, CP Goold, JM Thanos, T Fu, ...
bioRxiv, 231290, 2017
2017
Genetic Reporter Cell Lines: Tools for Stem Cell Biology and Drug Discovery
CPJ Hunt, B Watmuff, BJ Hartley, CW Pouton, JM Haynes
Neural Stem Cell Assays, 251-260, 2014
2014
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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