| Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade SA Hawley, J Boudeau, JL Reid, KJ Mustard, L Udd, TP Mäkelä, ... Journal of biology 2, 1-16, 2003 | 2083 | 2003 |
| LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1 JM Lizcano, O Göransson, R Toth, M Deak, NA Morrice, J Boudeau, ... The EMBO journal 23 (4), 833-843, 2004 | 1568 | 2004 |
| FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 782 | 2023 |
| Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox‐1 homeobox transcription factor TV Petrova, T Mäkinen, TP Mäkelä, J Saarela, I Virtanen, RE Ferrell, ... The EMBO journal, 2002 | 778 | 2002 |
| FGFR‐4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. J Partanen, TP Mäkelä, E Eerola, J Korhonen, H Hirvonen, ... The EMBO journal 10 (6), 1347-1354, 1991 | 655 | 1991 |
| A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains J Partanen, E Armstrong, TP Mäkelä, J Korhonen, M Sandberg, ... Molecular and cellular biology 12 (4), 1698-1707, 1992 | 504 | 1992 |
| Association of Cdk-activating kinase subunits with transcription factor TFIIH H Serizawa, TP Mäkelä, JW Conaway, RC Conaway, RA Weinberg, ... Nature 374 (6519), 280-282, 1995 | 481 | 1995 |
| Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts RE Herrera, VP Sah, BO Williams, TP Mäkelä, RA Weinberg, T Jacks Molecular and cellular biology, 1996 | 385 | 1996 |
| A cyclin associated with the CDK-activating kinase MO15 TP Mäkelä, JP Tassan, EA Nigg, S Frutiger, GJ Hughes, RA Weinberg Nature 371 (6494), 254-257, 1994 | 369 | 1994 |
| Growth suppression by Lkb1 is mediated by a G1 cell cycle arrest M Tiainen, A Ylikorkala, TP Mäkelä Proceedings of the National Academy of Sciences 96 (16), 9248-9251, 1999 | 366 | 1999 |
| Integrated network analysis platform for protein-protein interactions J Wu, T Vallenius, K Ovaska, J Westermarck, TP Mäkelä, S Hautaniemi Nature methods 6 (1), 75-77, 2009 | 360 | 2009 |
| Vascular Abnormalities and Deregulation of VEGF in Lkb1-Deficient Mice A Ylikorkala, DJ Rossi, N Korsisaari, K Luukko, K Alitalo, M Henkemeyer, ... Science 293 (5533), 1323-1326, 2001 | 357 | 2001 |
| FinnGen: Unique genetic insights from combining isolated population and national health register data MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, K Donner, ... MedRxiv, 2022.03. 03.22271360, 2022 | 354 | 2022 |
| PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis N Djouder, RD Tuerk, M Suter, P Salvioni, RF Thali, R Scholz, ... The EMBO journal 29 (2), 469-481, 2010 | 324 | 2010 |
| p21 inhibits Thr161 phosphorylation of Cdc2 to enforce the G2 DNA damage checkpoint VAJ Smits, R Klompmaker, T Vallenius, G Rijksen, TP Mäkelä, ... Journal of Biological Chemistry 275 (39), 30638-30643, 2000 | 299 | 2000 |
| BRCT domain-containing protein TopBP1 functions in DNA replication and damage response M Makiniemi, T Hillukkala, J Tuusa, K Reini, M Vaara, D Huang, ... Journal of Biological Chemistry 276 (32), 30399-30406, 2001 | 287 | 2001 |
| Requirement for TFIIH kinase activity in transcription by RNA polymerase II S Akoulitchev, TP Mäkelä, RA Weinberg, D Reinberg Nature 377 (6549), 557-560, 1995 | 286 | 1995 |
| Growth arrest by the LKB1 tumor suppressor: induction of p21WAF1/CIP1 M Tiainen, K Vaahtomeri, A Ylikorkala, TP Mäkelä Human molecular genetics 11 (13), 1497-1504, 2002 | 272 | 2002 |
| The apoptotic v-cyclin–CDK6 complex phosphorylates and inactivates Bcl-2 PM Ojala, K Yamamoto, E Castaños-Vélez, P Biberfeld, SJ Korsmeyer, ... Nature cell biology 2 (11), 819-825, 2000 | 214 | 2000 |
| Gene encoding a new RING-B-box-Coiled-coil protein is mutated in mulibrey nanism K Avela, M Lipsanen-Nyman, N Idänheimo, E Seemanová, S Rosengren, ... Nature genetics 25 (3), 298-301, 2000 | 191 | 2000 |
