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Michele Biagioli
Michele Biagioli
Email verificata su unipg.it
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Bile acids activated receptors regulate innate immunity
S Fiorucci, M Biagioli, A Zampella
Frontiers in immunology 9, 366411, 2018
3932018
The bile acid receptor GPBAR1 regulates the M1/M2 phenotype of intestinal macrophages and activation of GPBAR1 rescues mice from murine colitis
M Biagioli, A Carino, S Cipriani, D Francisci, S Marchianò, P Scarpelli, ...
The Journal of Immunology 199 (2), 718-733, 2017
2172017
Bile acids and their receptors in metabolic disorders
S Fiorucci, E Distrutti, A Carino, A Zampella, M Biagioli
Progress in Lipid Research 82, 101094, 2021
1392021
Bile acid signaling in inflammatory bowel diseases
S Fiorucci, A Carino, M Baldoni, L Santucci, E Costanzi, L Graziosi, ...
Digestive Diseases and Sciences 66, 674-693, 2021
1372021
GILZ promotes production of peripherally induced Treg cells and mediates the crosstalk between glucocorticoids and TGF-β signaling
O Bereshchenko, M Coppo, S Bruscoli, M Biagioli, M Cimino, ...
Cell reports 7 (2), 464-475, 2014
1312014
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
A Carino, S Cipriani, S Marchianò, M Biagioli, C Santorelli, A Donini, ...
Scientific Reports 7 (1), 42801, 2017
1162017
Hijacking SARS-CoV-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on the receptor binding domain
A Carino, F Moraca, B Fiorillo, S Marchianò, V Sepe, M Biagioli, ...
Frontiers in Chemistry 8, 572885, 2020
1012020
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH)
S Fiorucci, M Biagioli, V Sepe, A Zampella, E Distrutti
Expert Opinion on Investigational Drugs 29 (6), 623-632, 2020
802020
Future trends in the treatment of non-alcoholic steatohepatitis
S Fiorucci, M Biagioli, E Distrutti
Pharmacological research 134, 289-298, 2018
622018
Bile acids activated receptors in inflammatory bowel disease
M Biagioli, S Marchianò, A Carino, C Di Giorgio, L Santucci, E Distrutti, ...
Cells 10 (6), 1281, 2021
562021
Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice
S Bruscoli, M Biagioli, D Sorcini, T Frammartino, M Cimino, P Sportoletti, ...
Blood, The Journal of the American Society of Hematology 126 (15), 1790-1801, 2015
562015
Metabolic variability of a multispecies probiotic preparation impacts on the anti-inflammatory activity
M Biagioli, L Laghi, A Carino, S Cipriani, E Distrutti, S Marchianò, ...
Frontiers in pharmacology 8, 505, 2017
512017
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
A Carino, S Marchiano, M Biagioli, M Bucci, V Vellecco, V Brancaleone, ...
The FASEB Journal 33 (2), 2809-2822, 2019
502019
Signaling from intestine to the host: how bile acids regulate intestinal and liver immunity
M Biagioli, A Carino
Bile Acids and Their Receptors, 95-108, 2019
472019
Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
A Carino, S Cipriani, S Marchianò, M Biagioli, P Scarpelli, A Zampella, ...
Scientific reports 7 (1), 13689, 2017
462017
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH
A Carino, M Biagioli, S Marchianò, C Fiorucci, A Zampella, MC Monti, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019
442019
GPBAR1 functions as gatekeeper for liver NKT cells and provides counterregulatory signals in mouse models of immune-mediated hepatitis
M Biagioli, A Carino, C Fiorucci, S Marchianò, C Di Giorgio, R Roselli, ...
Cellular and Molecular Gastroenterology and Hepatology 8 (3), 447-473, 2019
432019
Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders
S Fiorucci, M Baldoni, P Ricci, A Zampella, E Distrutti, M Biagioli
Current Opinion in Pharmacology 53, 45-54, 2020
412020
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis
A Carino, M Biagioli, S Marchianò, C Fiorucci, M Bordoni, R Roselli, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020
302020
Novel isoxazole derivatives with potent FXR agonistic activity prevent acetaminophen-induced liver injury
V Sepe, S Marchianò, C Finamore, G Baronissi, FS Di Leva, A Carino, ...
ACS Medicinal Chemistry Letters 10 (4), 407-412, 2018
292018
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