| Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins M Pirazzini, G Zanetti, A Megighian, M Scorzeto, S Fillo, CC Shone, T Binz, ... Cell reports 8 (6), 1870-1878, 2014 | 116 | 2014 |
| On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments M Pirazzini, O Leka, G Zanetti, O Rossetto, C Montecucco Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (3), 467-474, 2016 | 106 | 2016 |
| The thioredoxin reductase–Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles M Pirazzini, G Zanetti, F Lista, T Binz, CC Shone, O Rossetto, ... Toxicon 107, 32-36, 2015 | 44 | 2015 |
| Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism G Zanetti, M Pirazzini, T Binz, CC Shone, S Fillo, F Lista, O Rossetto, ... Biochemical pharmacology 98 (3), 522-530, 2015 | 35 | 2015 |
| Variability in venom composition of European viper subspecies limits the cross-effectiveness of antivenoms G Zanetti, E Duregotti, CA Locatelli, A Giampreti, D Lonati, O Rossetto, ... Scientific reports 8 (1), 9818, 2018 | 34 | 2018 |
| A novel inhibitor prevents the peripheral neuroparalysis of botulinum neurotoxins D Azarnia Tehran, G Zanetti, O Leka, F Lista, S Fillo, T Binz, CC Shone, ... Scientific Reports 5 (1), 17513, 2015 | 34 | 2015 |
| Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction E Duregotti, G Zanetti, M Scorzeto, A Megighian, C Montecucco, ... Toxins 7 (12), 5322-5336, 2015 | 32 | 2015 |
| Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals M Pirazzini, G Zanetti, O Rossetto, C Montecucco Toxicon 147, 32-37, 2018 | 31 | 2018 |
| Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission G Zanetti, S Sikorra, A Rummel, N Krez, E Duregotti, S Negro, T Henke, ... PLoS pathogens 13 (8), e1006567, 2017 | 31 | 2017 |
| A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage G Zanetti, S Negro, A Megighian, A Mattarei, F Lista, S Fillo, M Rigoni, ... Annals of Clinical and Translational Neurology 6 (12), 2395-2402, 2019 | 19 | 2019 |
| An agonist of the CXCR4 receptor strongly promotes regeneration of degenerated motor axon terminals S Negro, G Zanetti, A Mattarei, A Valentini, A Megighian, G Tombesi, ... Cells 8 (10), 1183, 2019 | 15 | 2019 |
| Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle C Marchioretti, G Zanetti, M Pirazzini, G Gherardi, L Nogara, R Andreotti, ... Nature communications 14 (1), 602, 2023 | 9 | 2023 |
| Electrophysiological recordings of evoked end-plate potential on murine neuro-muscular synapse preparations G Zanetti, S Negro, A Megighian, M Pirazzini Bio-protocol 8 (8), e2803-e2803, 2018 | 9 | 2018 |
| Ablation of S1P3 receptor protects mouse soleus from age-related drop in muscle mass, force, and regenerative capacity M Bondì, E Germinario, M Pirazzini, G Zanetti, F Cencetti, C Donati, ... American Journal of Physiology-Cell Physiology 313 (1), C54-C67, 2017 | 9 | 2017 |
| A new transgenic mouse line for imaging mitochondrial calcium signals N Redolfi, E Greotti, G Zanetti, T Hochepied, C Fasolato, D Pendin, ... Function 2 (3), zqab012, 2021 | 8 | 2021 |
| Novel small molecule inhibitors that prevent the neuroparalysis of tetanus neurotoxin G Zanetti, A Mattarei, F Lista, O Rossetto, C Montecucco, M Pirazzini Pharmaceuticals 14 (11), 1134, 2021 | 6 | 2021 |
| Mouse phrenic nerve hemidiaphragm assay (MPN) G Zanetti, S Negro, M Pirazzini, P Caccin Bio-protocol 8 (5), e2759-e2759, 2018 | 6 | 2018 |
| Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins. Cell Rep. 2014; 8 (6): 1870–8 M Pirazzini, D Azarnia Tehran, G Zanetti, A Megighian, M Scorzeto, S Fillo, ... | 5 | |
| Molecular and toxicological study of Italian viper venom neurotoxicity M Pirazzini, G Zanetti, C Montecucco, CA Locatelli, D Lonati, O Rossetto Clinical Toxicology 55 (5), 484-484, 2017 | 1 | 2017 |
| A DARPin promotes faster onset of botulinum neurotoxin A1 action O Leka, Y Wu, G Zanetti, S Furler, T Reinberg, J Marinho, JV Schaefer, ... Nature Communications 14 (1), 8317, 2023 | | 2023 |
