|Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor|
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
|Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space|
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
|tcpl: the ToxCast pipeline for high-throughput screening data|
DL Filer, P Kothiya, RW Setzer, RS Judson, MT Martin
Bioinformatics 33 (4), 618-620, 2017
|Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses|
DM Rotroff, MT Martin, DJ Dix, DL Filer, KA Houck, TB Knudsen, NS Sipes, ...
Environmental science & technology 48 (15), 8706-8716, 2014
|Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II|
D Filer, HB Patisaul, T Schug, D Reif, K Thayer
Current opinion in pharmacology 19, 145-152, 2014
|Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program|
AL Karmaus, DL Filer, MT Martin, KA Houck
Food and Chemical Toxicology 92, 188-196, 2016
|High-throughput screening of chemical effects on steroidogenesis using H295R human adrenocortical carcinoma cells|
AL Karmaus, CM Toole, DL Filer, KC Lewis, MT Martin
Toxicological sciences 150 (2), 323-332, 2016
|Prioritizing environmental chemicals for obesity and diabetes outcomes research: a screening approach using ToxCast™ high-throughput data|
S Auerbach, D Filer, D Reif, V Walker, AC Holloway, J Schlezinger, ...
Environmental health perspectives 124 (8), 1141-1154, 2016
|Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat|
KB Paul, JM Hedge, C Macherla, DL Filer, E Burgess, SO Simmons, ...
Toxicology 312, 97-107, 2013
|The ToxCast™ Analysis Pipeline: An R Package for Processing and Modeling Chemical Screening Data|
DL Filer, P Kothiya, WR Setzer, RS Judson, MT Martin
Version 1, 2015-08, 2015
|Falciparum malaria from coastal Tanzania and Zanzibar remains highly connected despite effective control efforts on the archipelago|
AP Morgan, NF Brazeau, B Ngasala, LE Mhamilawa, M Denton, ...
Malaria journal 19 (1), 1-14, 2020
|Curation of food-relevant chemicals in ToxCast|
AL Karmaus, TD Trautman, M Krishan, DL Filer, LA Fix
Food and Chemical Toxicology 103, 174-182, 2017
|Projected t-SNE for batch correction|
E Aliverti, JL Tilson, DL Filer, B Babcock, A Colaneri, J Ocasio, ...
Bioinformatics 36 (11), 3522-3527, 2020
|The new toxcast analysis|
Available through filer. dayne@ epa. gov, 2019
|Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing|
DL Filer, F Kuo, AT Brandt, CR Tilley, PA Mieczkowski, JS Berg, ...
BMC bioinformatics 22 (1), 1-16, 2021
|Noninvasive prenatal exome sequencing diagnostic utility limited by sequencing depth and fetal fraction|
DL Filer, PA Mieczkowski, A Brandt, KL Gilmore, BC Powell, JS Berg, ...
Prenatal Diagnosis, 2021
|Tools and Statistical Approaches for Integrating DNA Sequencing into Clinical Care|
The University of North Carolina at Chapel Hill, 2021
|Noninvasive prenatal exome sequencing inefficient for detecting single-gene disorders--problems and possible solutions|
D Filer, PA Mieczkowski, A Brandt, KL Gilmore, BC Powell, JS Berg, ...
|Frisky CALF outruns LASSO|
CD Jeffries, JR Ford, JL Tilson, DO Perkins, D Bost, D Filer, ...
|Novel sequencing-based framework for non-invasive fetal genotyping|
DL Filer, KC Wilhelmsen, BC Powell, KL Gilmore, CM Powell, JS Berg, ...
American Journal of Obstetrics and Gynecology 222 (1), S497-S497, 2020