Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency HQ Mao, K Roy, VL Troung-Le, KA Janes, KY Lin, Y Wang, JT August, ... Journal of controlled release 70 (3), 399-421, 2001 | 1730 | 2001 |
Polysaccharide colloidal particles as delivery systems for macromolecules KA Janes, P Calvo, MJ Alonso Advanced drug delivery reviews 47 (1), 83-97, 2001 | 1251 | 2001 |
Chitosan nanoparticles as delivery systems for doxorubicin KA Janes, MP Fresneau, A Marazuela, A Fabra, MJ Alonso Journal of controlled Release 73 (2-3), 255-267, 2001 | 975 | 2001 |
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe Science 310 (5754), 1646-1653, 2005 | 640 | 2005 |
Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice A Vila, A Sánchez, K Janes, I Behrens, T Kissel, JLV Jato, MJ Alonso European Journal of pharmaceutics and biopharmaceutics 57 (1), 123-131, 2004 | 607 | 2004 |
Data-driven modelling of signal-transduction networks KA Janes, MB Yaffe Nature reviews Molecular cell biology 7 (11), 820-828, 2006 | 457 | 2006 |
Depolymerized chitosan nanoparticles for protein delivery: preparation and characterization KA Janes, MJ Alonso Journal of applied polymer science 88 (12), 2769-2776, 2003 | 257 | 2003 |
The response of human epithelial cells to TNF involves an inducible autocrine cascade KA Janes, S Gaudet, JG Albeck, UB Nielsen, DA Lauffenburger, ... Cell 124 (6), 1225-1239, 2006 | 254 | 2006 |
A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates MD Shults, KA Janes, DA Lauffenburger, B Imperiali Nature methods 2 (4), 277-284, 2005 | 249 | 2005 |
An analysis of critical factors for quantitative immunoblotting KA Janes Science signaling 8 (371), rs2-rs2, 2015 | 244 | 2015 |
Common effector processing mediates cell-specific responses to stimuli K Miller-Jensen, KA Janes, JS Brugge, DA Lauffenburger Nature 448 (7153), 604-608, 2007 | 227 | 2007 |
A Compendium of Signals and Responses Triggered by Prodeath and Prosurvival Cytokines S Gaudet, KA Janes, JG Albeck, EA Pace, DA Lauffenburger, PK Sorger Molecular & Cellular Proteomics 4 (10), 1569-1590, 2005 | 214 | 2005 |
Applying computational modeling to drug discovery and development N Kumar, BS Hendriks, KA Janes, D de Graaf, DA Lauffenburger Drug discovery today 11 (17-18), 806-811, 2006 | 169 | 2006 |
A biological approach to computational models of proteomic networks KA Janes, DA Lauffenburger Current opinion in chemical biology 10 (1), 73-80, 2006 | 148 | 2006 |
Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data KA Janes, JR Kelly, S Gaudet, JG Albeck, PK Sorger, DA Lauffenburger Journal of Computational Biology 11 (4), 544-561, 2004 | 141 | 2004 |
Intersection of FOXO-and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression L Wang, JS Brugge, KA Janes Proceedings of the National Academy of Sciences 108 (40), E803-E812, 2011 | 135 | 2011 |
Identifying single-cell molecular programs by stochastic profiling KA Janes, CC Wang, KJ Holmberg, K Cabral, JS Brugge Nature methods 7 (4), 311-317, 2010 | 134 | 2010 |
Astrocytic trans-differentiation completes a multicellular paracrine feedback loop required for medulloblastoma tumor growth M Yao, PB Ventura, Y Jiang, FJ Rodriguez, L Wang, JSA Perry, Y Yang, ... Cell 180 (3), 502-520. e19, 2020 | 122 | 2020 |
Automated brightfield morphometry of 3D organoid populations by OrganoSeg MA Borten, SS Bajikar, N Sasaki, H Clevers, KA Janes Scientific reports 8 (1), 5319, 2018 | 121 | 2018 |
A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis KA Janes, JG Albeck, LX Peng, PK Sorger, DA Lauffenburger, MB Yaffe Molecular & Cellular Proteomics 2 (7), 463-473, 2003 | 120 | 2003 |