| Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma LK Donovan, A Delaidelli, SK Joseph, K Bielamowicz, K Fousek, ... Nature medicine 26 (5), 720-731, 2020 | 161 | 2020 |
| A High-Quality Assembly of the Nine-Spined Stickleback (Pungitius pungitius) Genome S Varadharajan, P Rastas, A Löytynoja, M Matschiner, FCF Calboli, ... Genome Biology and Evolution 11 (11), 3291-3308, 2019 | 71 | 2019 |
| ZFTA–RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma A Arabzade, Y Zhao, S Varadharajan, HC Chen, S Jessa, B Rivas, ... Cancer discovery 11 (9), 2200-2215, 2021 | 54 | 2021 |
| The Grayling Genome Reveals Selection on Gene Expression Regulation after Whole-Genome Duplication S Varadharajan, SR Sandve, G Gillard, OK Tørresen, T Mulugeta, ... Genome Biology and Evolution 10 (10), 2785–2800, 2018 | 42 | 2018 |
| ZFTA Translocations Constitute Ependymoma Chromatin Remodeling and Transcription Factors R Kupp, L Ruff, S Terranova, E Nathan, S Ballereau, R Stark, ... Cancer discovery 11 (9), 2216-2229, 2021 | 40 | 2021 |
| Exploring in silico prediction of the unbound brain-to-plasma drug concentration ratio: model validation, renewal, and interpretation S Varadharajan, S Winiwarter, L Carlsson, O Engkvist, A Anantha, ... Journal of Pharmaceutical Sciences 104 (3), 1197-1206, 2015 | 37 | 2015 |
| K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas S Jessa, A Mohammadnia, AS Harutyunyan, M Hulswit, S Varadharajan, ... Nature genetics 54 (12), 1865-1880, 2022 | 35 | 2022 |
| Switching on the light: using metagenomic shotgun sequencing to characterize the intestinal microbiome of Atlantic cod ES Riiser, THA Haverkamp, S Varadharajan, Ø Borgan, KS Jakobsen, ... Environmental microbiology 21 (7), 2576-2594, 2019 | 31 | 2019 |
| The chromosome-level genome assembly of European grayling reveals aspects of a unique genome evolution process within salmonids T Sävilammi, CR Primmer, S Varadharajan, R Guyomard, Y Guiguen, ... G3: Genes, Genomes, Genetics 9 (5), 1283-1294, 2019 | 27 | 2019 |
| Metagenomic shotgun analyses reveal complex patterns of intra-and interspecific variation in the intestinal microbiomes of codfishes ES Riiser, THA Haverkamp, S Varadharajan, Ø Borgan, KS Jakobsen, ... Applied and Environmental Microbiology 86 (6), e02788-19, 2020 | 26 | 2020 |
| Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome BJ Golbourn, ME Halbert, K Halligan, S Varadharajan, B Krug, NE Mbah, ... Nature cancer 3 (5), 629-648, 2022 | 23 | 2022 |
| ZFTA-RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma. Cancer Discov. 2021; 11: 2200–2215. doi: 10.1158/2159-8290 A Arabzade, Y Zhao, S Varadharajan, HC Chen, S Jessa, B Rivas, ... CD-20-1066.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 7 | |
| ZFTA-RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma. Cancer Discov A Arabzade, Y Zhao, S Varadharajan, HC Chen, S Jessa, B Rivas, ... | 6 | 2021 |
| Sox9 directs divergent epigenomic states in brain tumor subtypes D Sardar, HC Chen, A Reyes, S Varadharajan, A Jain, C Mohila, R Curry, ... Proceedings of the National Academy of Sciences 119 (29), e2202015119, 2022 | 5 | 2022 |
| ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors. Cancer Discov R Kupp, L Ruff, S Terranova, E Nathan, S Ballereau, R Stark, ... | 5 | 2021 |
| Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma LK Donovan, A Delaidelli, SK Joseph, K Bielamowicz, K Fousek, ... Nature Medicine 27 (6), 1117-1120, 2021 | 2 | 2021 |
| Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome BJ Golbourn, ME Halbert, K Halligan, S Varadharajan, B Krug, NE Mbah, ... Nature Cancer 3 (7), 899-899, 2022 | 1 | 2022 |
| An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma SM Casillo, TA Gatesman, A Chilukuri, S Varadharajan, BJ Johnson, ... Cell Reports 43 (1), 2024 | | 2024 |
| ABSTRACT CITATION ID: NOAD073. 109 EPEN-05. TRANSCRIPTIONAL FACTOR-DIRECTED EPIGENETIC REGULATION IN CANCER NEUROSCIENCE OF ZFTA-RELA EPENDYMOMA HC Chen, M McDonald, S Varadharajan NEURO-ONCOLOGY, 2023 | | 2023 |
| EPEN-01. ZFTA-RELA FUSION PROGRAMS CONVERGE ON YAP PATHWAY ACTIVATION IN EPENDYMOMA A Stuckert, S Varadharajan, S Mack Neuro-Oncology 25 (Suppl 1), i26, 2023 | | 2023 |
Ola EngkvistAstraZeneca R&D Gothenburg Orcid:0000-0003-4970-6461Verified email at astrazeneca.com
