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Robert K McGinty
Robert K McGinty
Verified email at email.unc.edu - Homepage
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Cited by
Year
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
JC Scheuermann, AG de Ayala Alonso, K Oktaba, N Ly-Hartig, ...
Nature 465 (7295), 243-247, 2010
8522010
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
J Kim, M Guermah, RK McGinty, JS Lee, Z Tang, TA Milne, A Shilatifard, ...
Cell 137 (3), 459-471, 2009
5932009
Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
RK McGinty, J Kim, C Chatterjee, RG Roeder, TW Muir
Nature 453 (7196), 812-816, 2008
5932008
Nucleosome structure and function
RK McGinty, S Tan
Chemical reviews 115 (6), 2255-2273, 2015
5402015
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
B Fierz, C Chatterjee, RK McGinty, M Bar-Dagan, DP Raleigh, TW Muir
Nature chemical biology 7 (2), 113-119, 2011
4922011
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions
AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ...
Cell 145 (5), 692-706, 2011
3932011
Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
RK McGinty, RC Henrici, S Tan
Nature 514 (7524), 591-596, 2014
3152014
Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation
C Chatterjee, RK McGinty, B Fierz, TW Muir
Nature chemical biology 6 (4), 267-269, 2010
2632010
Auxiliary-mediated site-specific peptide ubiquitylation
C Chatterjee, RK McGinty, JP Pellois, TW Muir
Angewandte Chemie-International Edition 46 (16), 2814-2818, 2007
2082007
SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53
Z Tang, WY Chen, M Shimada, UTT Nguyen, J Kim, XJ Sun, T Sengoku, ...
Cell 154 (2), 297-310, 2013
1702013
Structural basis of nucleosome-dependent cGAS inhibition
JA Boyer, CJ Spangler, JD Strauss, AP Cesmat, P Liu, RK McGinty, ...
Science 370 (6515), 450-454, 2020
1552020
The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation
J Kim, JA Kim, RK McGinty, UTT Nguyen, TW Muir, CD Allis, RG Roeder
Molecular cell 49 (6), 1121-1133, 2013
1532013
Structure–activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B
RK McGinty, M Köhn, C Chatterjee, KP Chiang, MR Pratt, TW Muir
ACS chemical biology 4 (11), 958-968, 2009
1292009
Recognition of the nucleosome by chromatin factors and enzymes
RK McGinty, S Tan
Current Opinion in Structural Biology 37, 54-61, 2016
1152016
Structural basis for recognition of ubiquitylated nucleosome by Dot1L methyltransferase
CJ Anderson, MR Baird, A Hsu, EH Barbour, Y Koyama, MJ Borgnia, ...
Cell reports 26 (7), 1681-1690. e5, 2019
1102019
Principles of nucleosome recognition by chromatin factors and enzymes
RK McGinty, S Tan
Current opinion in structural biology 71, 16-26, 2021
732021
A Semi-Synthetic Strategy to Generate Phosphorylated and Acetylated Histone H2B
KP Chiang, MS Jensen, RK McGinty, TW Muir
Chembiochem: a European journal of chemical biology 10 (13), 2182, 2009
702009
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
A Skrajna, D Goldfarb, KM Kedziora, EM Cousins, GD Grant, CJ Spangler, ...
Nucleic acids research 48 (17), 9415-9432, 2020
692020
Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2
SJ Whitcomb, B Fierz, RK McGinty, M Holt, T Ito, TW Muir, CD Allis
Journal of Biological Chemistry 287 (28), 23718-23725, 2012
392012
Multivalent interactions by the Set8 histone methyltransferase with its nucleosome substrate
TS Girish, RK McGinty, S Tan
Journal of molecular biology 428 (8), 1531-1543, 2016
372016
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