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Malik M Keshwani
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Anno
PKA: lessons learned after twenty years
SS Taylor, P Zhang, JM Steichen, MM Keshwani, AP Kornev
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1271-1278, 2013
3102013
Evolution of the eukaryotic protein kinases as dynamic molecular switches
SS Taylor, MM Keshwani, JM Steichen, AP Kornev
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
2452012
Deciphering the structural basis of eukaryotic protein kinase regulation
HS Meharena, P Chang, MM Keshwani, K Oruganty, AK Nene, N Kannan, ...
PLoS biology 11 (10), e1001680, 2013
2112013
Structure and allostery of the PKA RIIβ tetrameric holoenzyme
P Zhang, EV Smith-Nguyen, MM Keshwani, MS Deal, AP Kornev, ...
Science 335 (6069), 712-716, 2012
1792012
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
YS Lee, H Morinaga, JJ Kim, W Lagakos, S Taylor, M Keshwani, ...
Cell 153 (2), 413-425, 2013
1512013
Structural basis for the regulation of protein kinase A by activation loop phosphorylation
JM Steichen, M Kuchinskas, MM Keshwani, J Yang, JA Adams, SS Taylor
Journal of Biological Chemistry 287 (18), 14672-14680, 2012
1072012
Release of SR proteins from CLK1 by SRPK1: a symbiotic kinase system for phosphorylation control of pre-mRNA splicing
BE Aubol, G Wu, MM Keshwani, M Movassat, L Fattet, KJ Hertel, XD Fu, ...
Molecular cell 63 (2), 218-228, 2016
912016
Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance
EJ Bae, J Xu, G Bandyopadhyay, WS Lagakos, M Keshwani, JM Olefsky
Journal of Biological Chemistry 287 (22), 18769-18780, 2012
772012
Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase
AC Bastidas, MS Deal, JM Steichen, MM Keshwani, Y Guo, SS Taylor
Journal of molecular biology 422 (2), 215-229, 2012
682012
Calcium-Dependent and -Independent Stomatal Signaling Network and Compensatory Feedback Control of Stomatal Opening via Ca2+ Sensitivity Priming
K Laanemets, B Brandt, J Li, E Merilo, YF Wang, MM Keshwani, SS Taylor, ...
Plant physiology 163 (2), 504-513, 2013
672013
Measurement of enzyme activity
TK Harris, MM Keshwani
Methods in enzymology 463, 57-71, 2009
632009
Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase
MM Keshwani, C Klammt, S von Daake, Y Ma, AP Kornev, S Choe, ...
Proceedings of the National Academy of Sciences 109 (20), E1221-E1229, 2012
562012
Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1)
MM Keshwani, S von Daake, AC Newton, TK Harris, SS Taylor
Journal of Biological Chemistry 286 (26), 23552-23558, 2011
512011
Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function
MM Keshwani, BE Aubol, L Fattet, CT Ma, J Qiu, PA Jennings, XD Fu, ...
Biochemical Journal 466 (2), 311-322, 2015
452015
N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation
BE Aubol, RM Plocinik, MM Keshwani, ML McGlone, JC Hagopian, ...
Biochemical Journal 462 (1), 143-152, 2014
392014
Directional phosphorylation and nuclear transport of the splicing factor SRSF1 is regulated by an RNA recognition motif
P Serrano, BE Aubol, MM Keshwani, S Forli, CT Ma, SK Dutta, M Geralt, ...
Journal of molecular biology 428 (11), 2430-2445, 2016
382016
Decoding the interactions regulating the active state mechanics of eukaryotic protein kinases
HS Meharena, X Fan, LG Ahuja, MM Keshwani, CL McClendon, AM Chen, ...
PLoS Biology 14 (11), e2000127, 2016
362016
Single turnover autophosphorylation cycle of the PKA RIIβ holoenzyme
P Zhang, MJ Knape, LG Ahuja, MM Keshwani, CC King, M Sastri, ...
PLoS biology 13 (7), e1002192, 2015
362015
Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination
X Xu, M Keshwani, K Meyer, A Sarikas, S Taylor, ZQ Pan
Journal of Biological Chemistry 287 (48), 40758-40766, 2012
342012
Mobilization of a splicing factor through a nuclear kinase–kinase complex
BE Aubol, MM Keshwani, L Fattet, JA Adams
Biochemical Journal 475 (3), 677-690, 2018
272018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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