| The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1 L Ge, J Wang, W Qi, HH Miao, J Cao, YX Qu, BL Li, BL Song Cell metabolism 7 (6), 508-519, 2008 | 417 | 2008 |
| Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer J Cao, Q Yan The key role of ubiquitination and sumoylation in signaling and cancer, 106, 2012 | 368 | 2012 |
| Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment Y Zheng, Z Chen, Y Han, L Han, X Zou, B Zhou, R Hu, J Hao, S Bai, ... Nature Communications 11 (1), 1-17, 2020 | 244 | 2020 |
| An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting J Cao, L Wu, SM Zhang, M Lu, WKC Cheung, W Cai, M Gale, Q Xu, Q Yan Nucleic Acids Research, gkw660, 2016 | 238 | 2016 |
| Cancer Epigenetics, Tumor Immunity, and Immunotherapy J Cao, Q Yan Trends in Cancer, 2020 | 204 | 2020 |
| Epigenetic regulation by lysine demethylase 5 (KDM5) enzymes in cancer LP Blair, J Cao, MR Zou, J Sayegh, Q Yan Cancers 3 (1), 1383-1404, 2011 | 176 | 2011 |
| Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 W Lin, J Cao, J Liu, ML Beshiri, Y Fujiwara, J Francis, AD Cherniack, ... Proceedings of the National Academy of Sciences 108 (33), 13379-13386, 2011 | 162 | 2011 |
| Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen J Sayegh, J Cao, MR Zou, A Morales, LP Blair, M Norcia, D Hoyer, ... Journal of Biological Chemistry 288 (13), 9408-9417, 2013 | 149 | 2013 |
| KDM5 histone demethylases repress immune response via suppression of STING L Wu, J Cao, WL Cai, SM Lang, JR Horton, DJ Jansen, ZZ Liu, JF Chen, ... PLoS biology 16 (8), e2006134, 2018 | 111 | 2018 |
| Histone demethylase RBP2 is critical for breast cancer progression and metastasis J Cao, Z Liu, WKC Cheung, M Zhao, SY Chen, SW Chan, CJ Booth, ... Cell reports 6 (5), 868-877, 2014 | 101 | 2014 |
| Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase J Cao, J Wang, W Qi, HH Miao, J Wang, L Ge, RA DeBose-Boyd, JJ Tang, ... Cell metabolism 6 (2), 115-128, 2007 | 100 | 2007 |
| Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. M Gale, J Sayegh, J Cao, M Norcia, P Gareiss, D Hoyer, JS Merkel, Q Yan Oncotarget, 2016 | 76 | 2016 |
| Association of the HTR2A gene with alcohol and heroin abuse J Cao, X Liu, S Han, CK Zhang, Z Liu, D Li Human genetics 133 (3), 357-365, 2014 | 71 | 2014 |
| Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response L Poillet-Perez, DW Sharp, Y Yang, SV Laddha, M Ibrahim, ... Nature Cancer 1 (9), 923-934, 2020 | 67 | 2020 |
| Associations of the 5‐hydroxytryptamine (serotonin) Receptor 1B gene (HTR1B) with alcohol, cocaine, and heroin abuse J Cao, E LaRocque, D Li American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 162 …, 2013 | 65 | 2013 |
| Multi-cultural association of the serotonin transporter gene (SLC6A4) with substance use disorder J Cao, JJ Hudziak, D Li Neuropsychopharmacology 38 (9), 1737-1747, 2013 | 59 | 2013 |
| Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes MR Zou, J Cao, Z Liu, SJ Huh, K Polyak, Q Yan Journal of Biological Chemistry 289 (25), 17620-17633, 2014 | 56 | 2014 |
| A virome-wide clonal integration analysis platform for discovering cancer viral etiology X Chen, J Kost, A Sulovari, N Wong, W Liang, J Cao, D Li Genome Research, gr. 242529.118, 2019 | 49 | 2019 |
| Size-dependent activation of CAR-T cells Q Xiao, X Zhang, L Tu, J Cao, CS Hinrichs, X Su Science Immunology 7 (74), eabl3995, 2022 | 41 | 2022 |
| Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function Y Zhang, JT Bailey, E Xu, K Singh, M Lavaert, VM Link, S D’Souza, ... Nature Immunology, 1-12, 2022 | 31 | 2022 |
Qin YanYale School of MedicineEmail verificata su yale.edu
