A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors A Aloia, D Müllhaupt, CD Chabbert, T Eberhart, S Flückiger-Mangual, ... Clinical Cancer Research 25 (22), 6852-6867, 2019 | 88 | 2019 |
Modulation and modeling of monoclonal antibody N‐linked glycosylation in mammalian cell perfusion reactors DJ Karst, E Scibona, E Serra, JM Bielser, J Souquet, M Stettler, H Broly, ... Biotechnology and Bioengineering 114 (9), 1978-1990, 2017 | 74 | 2017 |
Controlling the time evolution of mAb N‐linked glycosylation‐Part II: Model‐based predictions TK Villiger, E Scibona, M Stettler, H Broly, M Morbidelli, M Soos Biotechnology progress 32 (5), 1135-1148, 2016 | 57 | 2016 |
Mechanistic reconstruction of glycoprotein secretion through monitoring of intracellular N-glycan processing I Arigoni-Affolter, E Scibona, CW Lin, D Brühlmann, J Souquet, H Broly, ... Science advances 5 (11), eaax8930, 2019 | 42 | 2019 |
Influence of protein/glycan interaction on site‐specific glycan heterogeneity ME Losfeld, E Scibona, CW Lin, TK Villiger, R Gauss, M Morbidelli, ... The FASEB Journal 31 (10), 4623-4635, 2017 | 40 | 2017 |
Expansion processes for cell-based therapies E Scibona, M Morbidelli Biotechnology advances 37 (8), 107455, 2019 | 19 | 2019 |
Readily adsorbable thermoresponsive polymers for the preparation of smart cell-culturing surfaces on site M Sponchioni, N Manfredini, A Zanoni, E Scibona, M Morbidelli, ... ACS Biomaterials Science & Engineering 6 (9), 5337-5345, 2020 | 12 | 2020 |
110th Anniversary: Fast and Easy-to-Use Method for Coating Tissue Culture Polystyrene Surfaces with Nonfouling Copolymers To Prevent Cell Adhesion N Manfredini, E Scibona, M Morbidelli, D Moscatelli, M Sponchioni Industrial & Engineering Chemistry Research 58 (49), 22290-22298, 2019 | 10 | 2019 |
Modeling the Microenvironment-Dependent Degradation of Drug-Loaded Polylactic-co-glycolic Microparticles T Casalini, A Cingolani, E Scibona Industrial & Engineering Chemistry Research 60 (29), 10683-10698, 2021 | 3 | 2021 |
Glycosylation network mapping and site-specific glycan maturation in vivo ME Losfeld, E Scibona, C Lin, M Aebi Iscience 25 (11), 2022 | 2 | 2022 |
Process Performance Qualification Master Plan: Considerations for Gene Therapies BioPhorum, 2023 | | 2023 |
Minimizing the Impact of Stability Testing on Gene Therapy Batch Yield BioPhorum, 2023 | | 2023 |
Minimizing the Impact of CCIT on Gene Therapy Batch Yield BioPhorum, 2023 | | 2023 |
Site-specific N-glycosylation: kinetic analysis in vivo and influence of glycoprocessing enzymes expression ME Losfeld, I Arigoni-Affolter, E Scibona, R Hennig, E Rapp, M Aebi GLYCOBIOLOGY 30 (12), 1074-1075, 2020 | | 2020 |
Experimental and Modeling Framework for the Production of Cell and Protein-Based Biopharmaceutical Products E Scibona ETH Zurich, 2019 | | 2019 |
Time-resolved N-glycan processing allows a functional resolution of the Golgi in CHO cells I Affolter, CW Lin, E Scibona, D Bruhlmann, J Souquet, H Broly, M Aebi GLYCOBIOLOGY 27 (12), 1199-1199, 2017 | | 2017 |
High Density Ex Vivo Expansion Of Stem Cell Aggregates In Stirred Perfusion Bioreactors E Scibona, D Karst, M Morbidelli | | 2017 |
Modulation and mathematical prediction of monoclonal antibody N-linked glycosylation in continuous CHO cell culture E SCIBONA Politecnico di Milano, 2013 | | 2013 |