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Juan José Ramírez-Espinosa
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Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches
JJ Ramírez-Espinosa, MY Rios, S López-Martínez, F López-Vallejo, ...
European journal of medicinal chemistry 46 (6), 2243-2251, 2011
1432011
Chrysin induces antidiabetic, antidyslipidemic and anti-inflammatory effects in athymic nude diabetic mice
JJ Ramírez-Espinosa, J Saldaña-Ríos, S García-Jiménez, ...
Molecules 23 (1), 67, 2017
682017
Discovery of Thiazolidine‐2,4‐Dione/Biphenylcarbonitrile Hybrid as Dual PPAR α/γ Modulator with Antidiabetic Effect: In vitro, In Silico and In Vivo Approaches
S Hidalgo‐Figueroa, JJ Ramírez‐Espinosa, S Estrada‐Soto, ...
Chemical biology & drug design 81 (4), 474-483, 2013
622013
Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model
E Hernández-Vázquez, R Aguayo-Ortiz, JJ Ramírez-Espinosa, ...
European journal of medicinal chemistry 69, 10-21, 2013
472013
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition
JJ Ramírez-Espinosa, MY Rios, P Paoli, V Flores-Morales, G Camici, ...
European Journal of Medicinal Chemistry 87, 316-327, 2014
442014
Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl) amino]-1, 3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities
G Navarrete-Vázquez, MG Morales-Vilchis, S Estrada-Soto, ...
European Journal of Medicinal Chemistry 74, 179-186, 2014
382014
Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies
R Guzmán‐Ávila, V Flores‐Morales, P Paoli, G Camici, ...
Drug Development Research 79 (2), 70-80, 2018
352018
Synthesis and molecular docking of N′-arylidene-5-(4-chlorophenyl)-1-(3, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents
E Hernández-Vázquez, S Salgado-Barrera, JJ Ramírez-Espinosa, ...
Bioorganic & medicinal chemistry 24 (10), 2298-2306, 2016
342016
Synthesis and evaluation of thiazolidine-2, 4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular …
S Hidalgo-Figueroa, S Estrada-Soto, JJ Ramírez-Espinosa, P Paoli, ...
Biomedicine & Pharmacotherapy 107, 1302-1310, 2018
312018
Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect
G Navarrete-Vázquez, H Torres-Gómez, S Hidalgo-Figueroa, ...
Bioorganic & medicinal chemistry letters 24 (18), 4575-4579, 2014
312014
Antihyperglycemic and sub-chronic antidiabetic actions of morolic and moronic acids, in vitro and in silico inhibition of 11β-HSD 1
JJ Ramírez-Espinosa, S García-Jiménez, MY Rios, JL Medina-Franco, ...
Phytomedicine 20 (7), 571-576, 2013
312013
1, 5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies
E Hernández-Vázquez, R Castañeda-Arriaga, JJ Ramírez-Espinosa, ...
European journal of medicinal chemistry 100, 106-118, 2015
292015
In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives
L Cerón-Romero, P Paoli, G Camici, V Flores-Morales, MY Rios, ...
Bioorganic & Medicinal Chemistry Letters 26 (8), 2018-2022, 2016
252016
Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker
S Estrada-Soto, J Rivera-Leyva, JJ Ramírez-Espinosa, P Castillo-España, ...
Journal of Pharmacy and Pharmacology 62 (9), 1167-1174, 2010
252010
Synthesis and in vitro AMPK activation of cycloalkyl/alkarylbiguanides with robust in vivo antihyperglycemic action
E Gutierrez-Lara, C Martínez-Conde, E Rosales-Ortega, ...
Journal of Chemistry 2017, 2017
112017
Synthesis, in vitro, in silico and in vivo hypoglycemic and lipid-lowering effects of 4-benzyloxy-5-benzylidene-1, 3-thiazolidine-2, 4-diones mediated by dual PPAR α/γ modulation
JL Madrigal-Angulo, C Ménez-Guerrero, S Estrada-Soto, ...
Bioorganic & Medicinal Chemistry Letters 70, 128804, 2022
72022
Synthesis of 2-{2-[(a/b-naphthalen-yl} acetamides with 11b-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities q
G Navarrete-Vázquez, MG Morales-Vilchis, S Estrada-Soto, ...
European Journal of Medicinal Chemistry 74 (17), 9e186, 2014
22014
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTPe1B: In vitro, in silico, and in vivo approaches
JJ Ramírez-Espinosa, MY Rios, S López-Martínez, F López-Vallejo, ...
Eur. J. Med. Chem 46, 2243-2251, 2011
22011
Día del farmacéutico
JJ Ramirez Espinosa
Instituto de Ciencias Biomédicas, 2022
2022
Research Article Synthesis and In Vitro AMPK Activation of Cycloalkyl/Alkarylbiguanides with Robust In Vivo Antihyperglycemic Action
E Gutierrez-Lara, C Martínez-Conde, E Rosales-Ortega, ...
2017
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