Yoshitaka Fujihara
Yoshitaka Fujihara
Director, Department of Advanced Medical Technologies, NCVC
Verified email at - Homepage
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Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA
D Mashiko, Y Fujihara, Y Satouh, H Miyata, A Isotani, M Ikawa
Scientific reports 3, 3355, 2013
Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages
S Kobayashi, A Isotani, N Mise, M Yamamoto, Y Fujihara, K Kaseda, ...
Current Biology 16 (2), 166-172, 2006
SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia
Y Fujihara, Y Satouh, N Inoue, A Isotani, M Ikawa, M Okabe
Development 139 (19), 3583-3589, 2012
Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive
H Miyata, Y Satouh, D Mashiko, M Muto, K Nozawa, K Shiba, Y Fujihara, ...
Science 350 (6259), 442-445, 2015
Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice
H Miyata, JM Castaneda, Y Fujihara, Z Yu, DR Archambeault, A Isotani, ...
Proceedings of the National Academy of Sciences 113 (28), 7704-7710, 2016
Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa
Y Fujihara, K Tokuhiro, Y Muro, G Kondoh, Y Araki, M Ikawa, M Okabe
Proceedings of the National Academy of Sciences 110 (20), 8111-8116, 2013
Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm− oocyte fusion in mice
T Noda, Y Lu, Y Fujihara, S Oura, T Koyano, S Kobayashi, MM Matzuk, ...
Proceedings of the National Academy of Sciences 117 (21), 11493-11502, 2020
Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse
Y Fujihara, M Murakami, N Inoue, Y Satouh, K Kaseda, M Ikawa, M Okabe
Journal of cell science 123 (9), 1531-1536, 2010
CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice
A Oji, T Noda, Y Fujihara, H Miyata, YJ Kim, M Muto, K Nozawa, ...
Scientific reports 6, 31666, 2016
Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes
D Mashiko, SAM Young, M Muto, H Kato, K Nozawa, M Ogawa, T Noda, ...
Development, growth & differentiation 56 (1), 122-129, 2014
CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice
Y Lu, S Oura, T Matsumura, A Oji, N Sakurai, Y Fujihara, K Shimada, ...
Biology of reproduction 101 (2), 501-511, 2019
JunB is essential for IL-23-dependent pathogenicity of Th17 cells
Z Hasan, S Koizumi, D Sasaki, H Yamada, N Arakaki, Y Fujihara, S Okitsu, ...
Nature communications 8 (1), 15628, 2017
GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice
Y Fujihara, M Okabe, M Ikawa
Biology of reproduction 90 (3), 60, 1-6, 2014
Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice
Y Fujihara, Y Lu, T Noda, A Oji, T Larasati, K Kojima-Kita, Z Yu, ...
Proceedings of the National Academy of Sciences 117 (17), 9393-9400, 2020
Production of mouse pups from germline transmission-failed knockout chimeras
Y Fujihara, K Kaseda, N Inoue, M Ikawa, M Okabe
Transgenic research 22, 195-200, 2013
NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility
D Kiyozumi, T Noda, R Yamaguchi, T Tobita, T Matsumura, K Shimada, ...
Science 368 (6495), 1132-1135, 2020
A chromosome 16p13. 11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling
M Fujitani, S Zhang, R Fujiki, Y Fujihara, T Yamashita
Molecular Psychiatry 22 (3), 364–374, 2017
Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization
K Kato, Y Satouh, H Nishimasu, A Kurabayashi, J Morita, Y Fujihara, A Oji, ...
Nature Communications 7, 12198, 2016
GPI-AP release in cellular, developmental, and reproductive biology
Y Fujihara, M Ikawa
Journal of lipid research 57 (4), 538-545, 2016
CRISPR/Cas9-based genome editing in mice by single plasmid injection
Y Fujihara, M Ikawa
Methods in enzymology 546, 319-336, 2014
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