Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy I Karakikes, F Stillitano, M Nonnenmacher, C Tzimas, D Sanoudou, ... Nature communications 6 (1), 1-10, 2015 | 199 | 2015 |
Small molecule‐mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes I Karakikes, GD Senyei, J Hansen, CW Kong, EU Azeloglu, F Stillitano, ... Stem cells translational medicine 3 (1), 18-31, 2014 | 196 | 2014 |
Approaching clinical proteomics: current state and future fields of application in fluid proteomics R Apweiler, C Aslanidis, T Deufel, A Gerstner, J Hansen, D Hochstrasser, ... Clinical Chemistry and Laboratory Medicine (CCLM) 47 (6), 724-744, 2009 | 176 | 2009 |
Rationale and design of the Kidney Precision Medicine Project IH de Boer, CE Alpers, EU Azeloglu, UGJ Balis, JM Barasch, L Barisoni, ... Kidney international 99 (3), 498-510, 2021 | 103 | 2021 |
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells F Stillitano, J Hansen, CW Kong, I Karakikes, C Funck-Brentano, L Geng, ... Elife 6, e19406, 2017 | 95 | 2017 |
Approaching clinical proteomics: current state and future fields of application in cellular proteomics R Apweiler, C Aslanidis, T Deufel, A Gerstner, J Hansen, D Hochstrasser, ... Cytometry Part A: The Journal of the International Society for Advancement …, 2009 | 91 | 2009 |
A reference tissue atlas for the human kidney J Hansen, R Sealfon, R Menon, MT Eadon, BB Lake, B Steck, K Anjani, ... Science Advances 8 (23), eabn4965, 2022 | 75 | 2022 |
A comparison of mRNA sequencing with random primed and 3′-directed libraries Y Xiong, M Soumillon, J Wu, J Hansen, B Hu, JG Van Hasselt, ... Scientific reports 7 (1), 1-12, 2017 | 63 | 2017 |
Cell Type–Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease J Galatioto, CI Caescu, J Hansen, J Cook, I Miramontes, R Iyengar, ... Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA. 117.310609, 2018 | 54 | 2018 |
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project E Ong, LL Wang, J Schaub, JF O’Toole, B Steck, AZ Rosenberg, F Dowd, ... Nature Reviews Nephrology 16 (11), 686-696, 2020 | 49 | 2020 |
Computation as the mechanistic bridge between precision medicine and systems therapeutics J Hansen, R Iyengar Clinical Pharmacology & Therapeutics 93 (1), 117-128, 2013 | 46 | 2013 |
Characterization of a protein phosphatase 2A holoenzyme that dephosphorylates the clathrin adaptors AP-1 and AP-2 D Ricotta, J Hansen, C Preiss, D Teichert, S Höning Journal of Biological Chemistry 283 (9), 5510-5517, 2008 | 39 | 2008 |
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity JGC van Hasselt, R Rahman, J Hansen, A Stern, JV Shim, Y Xiong, ... Nature communications 11 (1), 1-12, 2020 | 36* | 2020 |
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact J Dave, N Raad, N Mittal, L Zhang, A Fargnoli, JG Oh, ME Savoia, ... Cardiovascular Research, 2022 | 28 | 2022 |
Functional Effects of Cardiomyocyte Injury in COVID-19 MM Siddiq, AT Chan, L Miorin, AS Yadaw, KG Beaumont, T Kehrer, ... Journal of Virology, JVI. 01063-21, 2021 | 28* | 2021 |
A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes J Hansen, D Meretzky, S Woldesenbet, G Stolovitzky, R Iyengar Scientific reports 7 (1), 1-13, 2017 | 27 | 2017 |
Systems pharmacology–based integration of human and mouse data for drug repurposing to treat thoracic aneurysms J Hansen, J Galatioto, CI Caescu, P Arnaud, RC Calizo, B Spronck, ... JCI insight 4 (11), 2019 | 25 | 2019 |
Systems pharmacology of complex diseases J Hansen, S Zhao, R Iyengar Annals of the New York Academy of Sciences 1245 (1), E1-E5, 2011 | 18 | 2011 |
Wilm’s tumor 1 promotes memory flexibility C Mariottini, L Munari, E Gunzel, JM Seco, N Tzavaras, J Hansen, ... Nature communications 10 (1), 1-18, 2019 | 16 | 2019 |
A Library Of Induced Pluripotent Stem Cells From Clinically Well-Characterized, Diverse Healthy Human Individuals C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunandan, DM Gonzalez, ... bioRxiv, 2020 | 15 | 2020 |