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Jens Hansen
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Anno
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy
I Karakikes, F Stillitano, M Nonnenmacher, C Tzimas, D Sanoudou, ...
Nature communications 6 (1), 1-10, 2015
1992015
Small molecule‐mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes
I Karakikes, GD Senyei, J Hansen, CW Kong, EU Azeloglu, F Stillitano, ...
Stem cells translational medicine 3 (1), 18-31, 2014
1962014
Approaching clinical proteomics: current state and future fields of application in fluid proteomics
R Apweiler, C Aslanidis, T Deufel, A Gerstner, J Hansen, D Hochstrasser, ...
Clinical Chemistry and Laboratory Medicine (CCLM) 47 (6), 724-744, 2009
1762009
Rationale and design of the Kidney Precision Medicine Project
IH de Boer, CE Alpers, EU Azeloglu, UGJ Balis, JM Barasch, L Barisoni, ...
Kidney international 99 (3), 498-510, 2021
1032021
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
F Stillitano, J Hansen, CW Kong, I Karakikes, C Funck-Brentano, L Geng, ...
Elife 6, e19406, 2017
942017
Approaching clinical proteomics: current state and future fields of application in cellular proteomics
R Apweiler, C Aslanidis, T Deufel, A Gerstner, J Hansen, D Hochstrasser, ...
Cytometry Part A: The Journal of the International Society for Advancement …, 2009
912009
A reference tissue atlas for the human kidney
J Hansen, R Sealfon, R Menon, MT Eadon, BB Lake, B Steck, K Anjani, ...
Science Advances 8 (23), eabn4965, 2022
742022
A comparison of mRNA sequencing with random primed and 3′-directed libraries
Y Xiong, M Soumillon, J Wu, J Hansen, B Hu, JG Van Hasselt, ...
Scientific reports 7 (1), 1-12, 2017
622017
Cell Type–Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease
J Galatioto, CI Caescu, J Hansen, J Cook, I Miramontes, R Iyengar, ...
Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA. 117.310609, 2018
542018
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project
E Ong, LL Wang, J Schaub, JF O’Toole, B Steck, AZ Rosenberg, F Dowd, ...
Nature Reviews Nephrology 16 (11), 686-696, 2020
492020
Computation as the mechanistic bridge between precision medicine and systems therapeutics
J Hansen, R Iyengar
Clinical Pharmacology & Therapeutics 93 (1), 117-128, 2013
462013
Characterization of a protein phosphatase 2A holoenzyme that dephosphorylates the clathrin adaptors AP-1 and AP-2
D Ricotta, J Hansen, C Preiss, D Teichert, S Höning
Journal of Biological Chemistry 283 (9), 5510-5517, 2008
392008
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity
JGC van Hasselt, R Rahman, J Hansen, A Stern, JV Shim, Y Xiong, ...
Nature communications 11 (1), 1-12, 2020
36*2020
Gene editing reverses arrhythmia susceptibility in humanized PLN-R14del mice: modelling a European cardiomyopathy with global impact
J Dave, N Raad, N Mittal, L Zhang, A Fargnoli, JG Oh, ME Savoia, ...
Cardiovascular Research, 2022
282022
Functional Effects of Cardiomyocyte Injury in COVID-19
MM Siddiq, AT Chan, L Miorin, AS Yadaw, KG Beaumont, T Kehrer, ...
Journal of Virology, JVI. 01063-21, 2021
28*2021
A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes
J Hansen, D Meretzky, S Woldesenbet, G Stolovitzky, R Iyengar
Scientific reports 7 (1), 1-13, 2017
272017
Systems pharmacology–based integration of human and mouse data for drug repurposing to treat thoracic aneurysms
J Hansen, J Galatioto, CI Caescu, P Arnaud, RC Calizo, B Spronck, ...
JCI insight 4 (11), 2019
252019
Systems pharmacology of complex diseases
J Hansen, S Zhao, R Iyengar
Annals of the New York Academy of Sciences 1245 (1), E1-E5, 2011
182011
Wilm’s tumor 1 promotes memory flexibility
C Mariottini, L Munari, E Gunzel, JM Seco, N Tzavaras, J Hansen, ...
Nature communications 10 (1), 1-18, 2019
162019
A Library Of Induced Pluripotent Stem Cells From Clinically Well-Characterized, Diverse Healthy Human Individuals
C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunandan, DM Gonzalez, ...
bioRxiv, 2020
152020
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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