Roberto Chiesa
Roberto Chiesa
Laboratory of Prion Neurobiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan
Verified email at marionegri.it - Homepage
TitleCited byYear
Neurotoxicity of a prion protein fragment
G Forloni, N Angeretti, R Chiesa, E Monzani, M Salmona, O Bugiani, ...
Nature 362 (6420), 543, 1993
10551993
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein
C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ...
Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010
3982010
Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35.
G Forloni, R Chiesa, S Smiroldo, L Verga, M Salmona, F Tagliavini, ...
Neuroreport 4 (5), 523-526, 1993
3891993
Neurological illness in transgenic mice expressing a prion protein with an insertional mutation
R Chiesa, P Piccardo, B Ghetti, DA Harris
Neuron 21 (6), 1339-1351, 1998
3311998
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation
B Drisaldi, RS Stewart, C Adles, LR Stewart, E Quaglio, E Biasini, L Fioriti, ...
Journal of Biological Chemistry 278 (24), 21732-21743, 2003
2472003
Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105–125
A Li, HM Christensen, LR Stewart, KA Roth, R Chiesa, DA Harris
The EMBO journal 26 (2), 548-558, 2007
2102007
Evidence for a six-transmembrane domain structure of presenilin 1
S Lehmann, R Chiesa, DA Harris
Journal of Biological Chemistry 272 (18), 12047-12051, 1997
1981997
Prion diseases: what is the neurotoxic molecule?
R Chiesa, DA Harris
Neurobiology of disease 8 (5), 743-763, 2001
1912001
Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform
E Quaglio, R Chiesa, DA Harris
Journal of Biological Chemistry 276 (14), 11432, 2001
1912001
Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation
R Chiesa, B Drisaldi, E Quaglio, A Migheli, P Piccardo, B Ghetti, DA Harris
Proceedings of the National Academy of Sciences 97 (10), 5574-5579, 2000
1602000
Molecular distinction between pathogenic and infectious properties of the prion protein
R Chiesa, P Piccardo, E Quaglio, B Drisaldi, M Takao, B Ghetti, DA Harris
Journal of virology 77 (13), 7611-7622, 2003
1492003
Monoclonal antibodies to human DNA topoisomerase I and the two isoforms of DNA topoisomerase II: 170-and 180-kDa isozymes
C Negri, R Chiesa, A Cerino, M Bestagno, C Sala, N Zini, NM Maraldi, ...
Experimental cell research 200 (2), 452-459, 1992
1331992
Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations
L Fioriti, S Dossena, LR Stewart, RS Stewart, DA Harris, G Forloni, ...
Journal of Biological Chemistry 280 (12), 11320-11328, 2005
1222005
A neurotoxic prion protein fragment induces rat astroglial proliferation and hypertrophy
G Forloni, R Del Bo, N Angeretti, R Chiesa, S Smiroldo, R Doni, ...
European Journal of Neuroscience 6 (9), 1415-1422, 1994
1211994
Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein
A Orsi, L Fioriti, R Chiesa, R Sitia
Journal of Biological Chemistry 281 (41), 30431-30438, 2006
1102006
Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease
R Chiesa, P Piccardo, S Dossena, L Nowoslawski, KA Roth, B Ghetti, ...
Proceedings of the National Academy of Sciences 102 (1), 238-243, 2005
1022005
Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model
S Dossena, L Imeri, M Mangieri, A Garofoli, L Ferrari, A Senatore, ...
Neuron 60 (4), 598-609, 2008
942008
Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells
E Biasini, L Fioriti, I Ceglia, R Invernizzi, A Bertoli, R Chiesa, G Forloni
Journal of neurochemistry 88 (3), 545-553, 2004
752004
Activation effects of a prion protein fragment [PrP-(106-126)] on human leucocytes
L Diomede, S Sozzani, W Luini, M Algeri, L De Gioia, R Chiesa, ...
Biochemical journal 320 (2), 563-570, 1996
651996
Neuroprotective effect of somatostatin on nonapoptotic NMDA‐induced neuronal death: role of cyclic GMP
G Forloni, E Lucca, N Angeretti, R Chiesa, A Vezzani
Journal of neurochemistry 68 (1), 319-327, 1997
641997
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Articles 1–20