| Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human … Y Koh, H Nakata, K Maeda, H Ogata, G Bilcer, T Devasamudram, ... Antimicrobial agents and chemotherapy 47 (10), 3123-3129, 2003 | 461 | 2003 |
| Efficacy of antibodies and antiviral drugs against Covid-19 Omicron variant E Takashita, N Kinoshita, S Yamayoshi, Y Sakai-Tagawa, S Fujisaki, M Ito, ... New England Journal of Medicine 386 (10), 995-998, 2022 | 361 | 2022 |
| Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity M Ohno, I Yamaguchi, I Yamamoto, T Fukuda, S Yokota, R Maekura, M Ito, ... The international journal of tuberculosis and lung disease 4 (3), 256-261, 2000 | 347 | 2000 |
| Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro K Maeda, H Nakata, Y Koh, T Miyakawa, H Ogata, Y Takaoka, ... Journal of virology 78 (16), 8654-8662, 2004 | 301 | 2004 |
| Efficacy of antiviral agents against the SARS-CoV-2 omicron subvariant BA. 2 E Takashita, N Kinoshita, S Yamayoshi, Y Sakai-Tagawa, S Fujisaki, M Ito, ... New England Journal of Medicine 386 (15), 1475-1477, 2022 | 283 | 2022 |
| Effect of SLCO1B3 Haplotype on Testosterone Transport and Clinical Outcome in Caucasian Patients with Androgen-Independent Prostatic Cancer A Hamada, T Sissung, DK Price, R Danesi, CH Chau, N Sharifi, D Venzon, ... Clinical cancer research 14 (11), 3312-3318, 2008 | 232 | 2008 |
| Comparison of rapid antigen tests for COVID-19 S Yamayoshi, Y Sakai-Tagawa, M Koga, O Akasaka, I Nakachi, H Koh, ... Viruses 12 (12), 1420, 2020 | 230 | 2020 |
| Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA. 2 R Uraki, M Kiso, S Iida, M Imai, E Takashita, M Kuroda, PJ Halfmann, ... Nature 607 (7917), 119-127, 2022 | 217 | 2022 |
| Structural and molecular interactions of CCR5 inhibitors with CCR5 K Maeda, D Das, H Ogata-Aoki, H Nakata, T Miyakawa, Y Tojo, R Norman, ... Journal of Biological Chemistry 281 (18), 12688-12698, 2006 | 206 | 2006 |
| Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5 K Maeda, K Yoshimura, S Shibayama, H Habashita, H Tada, K Sagawa, ... Journal of Biological Chemistry 276 (37), 35194-35200, 2001 | 187 | 2001 |
| A potent human immunodeficiency virus type 1 protease inhibitor, UIC-94003 (TMC-126), and selection of a novel (A28S) mutation in the protease active site K Yoshimura, R Kato, MF Kavlick, A Nguyen, V Maroun, K Maeda, ... Journal of virology 76 (3), 1349-1358, 2002 | 174 | 2002 |
| Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance AK Ghosh, PR Sridhar, S Leshchenko, AK Hussain, J Li, AY Kovalevsky, ... Journal of medicinal chemistry 49 (17), 5252-5261, 2006 | 170 | 2006 |
| Stacking-fault energy of II–VI compounds S Takeuchi, K Suzuki, K Maeda, H Iwanaga Philosophical Magazine A 50 (2), 171-178, 1985 | 163 | 1985 |
| A high-spin form of cytochrome P-450 highly purified from polychlorinated biphenyl-treated rats. Catalytic characterization and immunochemical quantitation in liver microsomes. T Kamataki, K Maeda, Y Yamazoe, N Matsuda, K Ishii, R Kato Molecular Pharmacology 24 (1), 146-155, 1983 | 162 | 1983 |
| Antibody titers against SARS-CoV-2 decline, but do not disappear for several months S Yamayoshi, A Yasuhara, M Ito, O Akasaka, M Nakamura, I Nakachi, ... EClinicalMedicine 32, 2021 | 149 | 2021 |
| Near-field tsunami forecasting using offshore tsunami data from the 2011 off the Pacific coast of Tohoku Earthquake H Tsushima, K Hirata, Y Hayashi, Y Tanioka, K Kimura, S Sakai, ... Earth, planets and space 63, 821-826, 2011 | 133 | 2011 |
| Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2′-ligands AK Ghosh, G Schiltz, RS Perali, S Leshchenko, S Kay, DE Walters, Y Koh, ... Bioorganic & medicinal chemistry letters 16 (7), 1869-1873, 2006 | 112 | 2006 |
| Design, synthesis, and biological evaluation of the combinatorial library with a new spirodiketopiperazine scaffold. Discovery of novel potent and selective low-molecular … H Habashita, M Kokubo, S Hamano, N Hamanaka, M Toda, S Shibayama, ... Journal of medicinal chemistry 49 (14), 4140-4152, 2006 | 104 | 2006 |
| Tsunami source area of the 2011 off the Pacific coast of Tohoku Earthquake determined from tsunami arrival times at offshore observation stations Y Hayashi, H Tsushima, K Hirata, K Kimura, K Maeda Earth, Planets and Space 63, 809-813, 2011 | 97 | 2011 |
| Discovery and development of anti-HIV therapeutic agents: progress towards improved HIV medication K Maeda, D Das, T Kobayakawa, H Tamamura, H Takeuchi Current Topics in Medicinal Chemistry 19 (18), 1621-1649, 2019 | 84 | 2019 |
