Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBβ) H Cho, J Mu, JK Kim, JL Thorvaldsen, Q Chu, EB Crenshaw III, ... Science 292 (5522), 1728-1731, 2001 | 2343 | 2001 |
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus Y Minokoshi, T Alquier, N Furukawa, YB Kim, A Lee, B Xue, J Mu, ... Nature 428 (6982), 569-574, 2004 | 1996 | 2004 |
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint RG Jones, DR Plas, S Kubek, M Buzzai, J Mu, Y Xu, MJ Birnbaum, ... Molecular cell 18 (3), 283-293, 2005 | 1920 | 2005 |
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation H Zong, JM Ren, LH Young, M Pypaert, J Mu, MJ Birnbaum, GI Shulman Proceedings of the national academy of sciences 99 (25), 15983-15987, 2002 | 1232 | 2002 |
A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle J Mu, JT Brozinick, O Valladares, M Bucan, MJ Birnbaum Molecular cell 7 (5), 1085-1094, 2001 | 1149 | 2001 |
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury RR Russell, J Li, DL Coven, M Pypaert, C Zechner, M Palmeri, ... The Journal of clinical investigation 114 (4), 495-503, 2004 | 874 | 2004 |
Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic β-cell mass and function in a rodent model of type 2 diabetes J Mu, J Woods, YP Zhou, RS Roy, Z Li, E Zycband, Y Feng, L Zhu, C Li, ... Diabetes 55 (6), 1695-1704, 2006 | 625 | 2006 |
The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity B Viollet, F Andreelli, SB Jørgensen, C Perrin, A Geloen, D Flamez, J Mu, ... The Journal of clinical investigation 111 (1), 91-98, 2003 | 617 | 2003 |
Exercise induces isoform-specific increase in 5′ AMP-activated protein kinase activity in human skeletal muscle N Fujii, T Hayashi, MF Hirshman, JT Smith, SA Habinowski, L Kaijser, ... Biochemical and biophysical research communications 273 (3), 1150-1155, 2000 | 479 | 2000 |
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B SS Bae, H Cho, J Mu, MJ Birnbaum Journal of Biological Chemistry 278 (49), 49530-49536, 2003 | 429 | 2003 |
Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor γ and altered metabolic states ES Muise, B Azzolina, DW Kuo, M El-Sherbeini, Y Tan, X Yuan, J Mu, ... Molecular pharmacology 74 (2), 403-412, 2008 | 362 | 2008 |
The regulation of AMP-activated protein kinase by H2O2 SL Choi, SJ Kim, KT Lee, J Kim, J Mu, MJ Birnbaum, SS Kim, J Ha Biochemical and biophysical research communications 287 (1), 92-97, 2001 | 347 | 2001 |
Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis in 3T3-L1 adipocytes W Yin, J Mu, MJ Birnbaum Journal of Biological Chemistry 278 (44), 43074-43080, 2003 | 342 | 2003 |
Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models B Viollet, F Andreelli, SB Jørgensen, C Perrin, D Flamez, J Mu, ... Biochemical Society Transactions 31 (1), 216-219, 2003 | 286 | 2003 |
Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia SL Conarello, G Jiang, J Mu, Z Li, J Woods, E Zycband, J Ronan, F Liu, ... Diabetologia 50, 142-150, 2007 | 252 | 2007 |
FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents J Mu, J Pinkstaff, Z Li, L Skidmore, N Li, H Myler, Q Dallas-Yang, ... Diabetes 61 (2), 505-512, 2012 | 208 | 2012 |
The PP2A-associated protein α4 is an essential inhibitor of apoptosis M Kong, CJ Fox, J Mu, L Solt, A Xu, RM Cinalli, MJ Birnbaum, T Lindsten, ... Science 306 (5696), 695-698, 2004 | 193 | 2004 |
Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes J Mu, A Petrov, GJ Eiermann, J Woods, YP Zhou, Z Li, E Zycband, Y Feng, ... European journal of pharmacology 623 (1-3), 148-154, 2009 | 187 | 2009 |
Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae C Cheng, J Mu, I Farkas, D Huang, MG Goebl, PJ Roach Molecular and Cellular Biology, 1995 | 131 | 1995 |
Selective suppression of AMP-activated protein kinase in skeletal muscle: update on ‘lazy mice’ J Mu, ER Barton, MJ Birnbaum Biochemical Society Transactions 31 (1), 236-241, 2003 | 130 | 2003 |